Summary
The literature section presents previous knowledge about this protein. There have been five different efforts to annotate minimal organism genome. The annotations from those efforts are given in the Literature section for completeness.
AVX54622.1
JCVISYN3A_0116
Uncharacterized protein.
M. mycoides homolog: Q6MUC1.
TIGRfam Classification: 1=Unknown.
Category: Quasiessential.
Statistics
Total GO Annotation: 17
Unique PROST Go: 17
Unique BLAST Go: 0
Unique Foldseek Go: 0
Total Homologs: 27
Unique PROST Homologs: 27
Unique BLAST Homologs: 0
Unique Foldseek Homologs: 0
Structures and Sequence Alignment
The best structural homolog that predicted by 5. P was
Q6CLZ3
(Inner membrane assembly complex subunit 17) with a FATCAT P-Value: 8.32e-06 and RMSD of 2.45 angstrom. The sequence alignment identity is 26.7%.
Structural alignment shown in left. Query protein AVX54622.1 colored as red in alignment, homolog Q6CLZ3 colored as blue.
Query protein AVX54622.1 is also shown in right top, homolog Q6CLZ3 showed in right bottom. They are colored based on secondary structures.
AVX54622.1 MQNKSGLI--LLKEV----FI---NNYSN-KIDFLKTVFSDKQINELESITNI--KELLTNL---K--EL-LDNQILIHQNKIKEYQLELKKTN----KK 78 Q6CLZ3 ------MFRPLVKRVVTRRFLAAANN-SNAHIE-IRTL-ED--LAKLQSLDNVDPK-LISKLINDKTNELNIKNEL----QMLKQLQAEEQKTQETSLKK 84 AVX54622.1 ILNKLWLWWLLPIIGMFIFFIIYNTRLQNPYYANQLVDIKVKITDLDIKNIYIDKL--LE-EI-------NSSV---K---------LKF- 146 Q6CLZ3 FVRPAWI-FLL--MGS----IVY---L-SCHYVWWKLDYEEK--ELE----YTHKVHQLESELAALNEAHNSSVSSDKNSKRSSRKWYKFW 158
Go Annotations
1. PBF indicates the go terms that are found by both PROST and BLAST and Foldseek.
2. PF indicates the go terms that are found by only PROST and Foldseek.
3. BF indicates the go terms that are found by only BLAST and Foldseek.
4. PB indicates the go terms that are found by both PROST and BLAST.
5. P indicates the go terms that are found by only PROST.
6. F indicates the go terms that are found by only Foldseek.
7. B indicates the go terms that are found by only BLAST.
| Source | GO | Description |
|---|---|---|
| 5. P | GO:0033615 | mitochondrial proton-transporting ATP synthase complex assembly |
| 5. P | GO:0016021 | integral component of membrane |
| 5. P | GO:0070072 | vacuolar proton-transporting V-type ATPase complex assembly |
| 5. P | GO:0044177 | host cell Golgi apparatus |
| 5. P | GO:0007035 | vacuolar acidification |
| 5. P | GO:0046686 | response to cadmium ion |
| 5. P | GO:0000746 | conjugation |
| 5. P | GO:0020002 | host cell plasma membrane |
| 5. P | GO:0005783 | endoplasmic reticulum |
| 5. P | GO:1990871 | Vma12-Vma22 assembly complex |
| 5. P | GO:0039503 | suppression by virus of host innate immune response |
| 5. P | GO:0012505 | endomembrane system |
| 5. P | GO:0019028 | viral capsid |
| 5. P | GO:0019386 | methanogenesis, from carbon dioxide |
| 5. P | GO:0030176 | integral component of endoplasmic reticulum membrane |
| 5. P | GO:1990524 | INA complex |
| 5. P | GO:0030269 | tetrahydromethanopterin S-methyltransferase activity |
Uniprot GO Annotations
| GO | Description |
|---|---|
| GO:0016020 | membrane |
| GO:0016021 | integral component of membrane |
Homologs
1. PBF indicates the homologs that are found by both PROST and BLAST and Foldseek.
2. PF indicates the homologs that are found by only PROST and Foldseek.
3. BF indicates the homologs that are found by only BLAST and Foldseek.
4. PB indicates the homologs that are found by both PROST and BLAST.
5. P indicates the homologs that are found by only PROST.
6. F indicates the homologs that are found by only Foldseek.
7. B indicates the homologs that are found by only BLAST.
| Source | Homolog | Description | Fatcat Pvalue | PROST Evalue | BLAST Evalue | Foldseek TMScore |
|---|---|---|---|---|---|---|
| 5. P | P32341 | Vacuolar ATPase assembly integral membrane protein VPH2 | 2.76e-04 | 6.90e-04 | NA | NA |
| 5. P | P14493 | 22 kDa relaxation protein | 3.17e-04 | 2.20e-07 | NA | NA |
| 5. P | P31972 | Uncharacterized protein SYNPCC7002_A1392 | 7.34e-03 | 1.45e-03 | NA | NA |
| 5. P | A5PK14 | Leucine-rich single-pass membrane protein 1 | 7.70e-05 | 3.70e-05 | NA | NA |
| 5. P | P16536 | 14 kDa peptide of ubiquinol-cytochrome c2 oxidoreductase complex | 7.25e-04 | 9.43e-06 | NA | NA |
| 5. P | Q04685 | Non-structural protein P8 | NA | 3.83e-05 | NA | NA |
| 5. P | O27225 | Tetrahydromethanopterin S-methyltransferase subunit G | 4.44e-05 | 7.49e-03 | NA | NA |
| 5. P | O74920 | Vacuolar ATPase assembly integral membrane protein vph2 | 1.22e-03 | 1.09e-02 | NA | NA |
| 5. P | Q04684 | Non-structural protein P8 | NA | 4.69e-02 | NA | NA |
| 5. P | Q6FRU5 | Inner membrane assembly complex subunit 17 | 2.28e-05 | 4.08e-03 | NA | NA |
| 5. P | P13659 | Mobilization protein MbeB | 9.57e-06 | 1.99e-11 | NA | NA |
| 5. P | P56621 | Nickel and cobalt resistance protein CnrY | 4.89e-04 | 1.18e-09 | NA | NA |
| 5. P | Q04686 | Non-structural protein P8 | NA | 1.40e-05 | NA | NA |
| 5. P | P22901 | Protein MobE | 5.05e-05 | 4.27e-11 | NA | NA |
| 5. P | P13841 | Non-structural protein P8 | NA | 4.62e-05 | NA | NA |
| 5. P | P23705 | Non-structural protein P8 | NA | 3.69e-04 | NA | NA |
| 5. P | Q3UQS2 | Leucine-rich single-pass membrane protein 1 | 1.11e-04 | 1.68e-02 | NA | NA |
| 5. P | O67738 | Uncharacterized protein aq_1900 | 5.14e-06 | 4.26e-02 | NA | NA |
| 5. P | Q04687 | Non-structural protein P8 | NA | 1.83e-04 | NA | NA |
| 5. P | Q64919 | Non-structural protein NS3 | NA | 7.34e-03 | NA | NA |
| 5. P | P08363 | Non-structural protein P8 | NA | 8.26e-06 | NA | NA |
| 5. P | P81328 | Uncharacterized protein MJ1417.1 | 4.13e-05 | 5.06e-09 | NA | NA |
| 5. P | Q6CLZ3 | Inner membrane assembly complex subunit 17 | 8.32e-06 | 4.40e-04 | NA | NA |
| 5. P | Q44581 | Nickel-cobalt-cadmium resistance protein NccY | 1.44e-03 | 3.14e-05 | NA | NA |
| 5. P | Q49329 | Uncharacterized protein MG269.1 | 2.16e-02 | 7.84e-15 | NA | NA |
| 5. P | P07113 | Mobilization protein B | 3.06e-05 | 8.13e-10 | NA | NA |
| 5. P | P20223 | Structural protein VP1 | NA | 1.22e-03 | NA | NA |