Results | PROST

Summary

The literature section presents previous knowledge about this protein. There have been five different efforts to annotate minimal organism genome. The annotations from those efforts are given in the Literature section for completeness.

AVX54668.1

JCVISYN3A_0221

Pyruvate kinase.
M. mycoides homolog: Q6MTY4.
TIGRfam Classification: 5=Equivalog.
Category: Essential.

Statistics

Total GO Annotation: 66
Unique PROST Go: 0
Unique BLAST Go: 1
Unique Foldseek Go: 18

Total Homologs: 250
Unique PROST Homologs: 0
Unique BLAST Homologs: 3
Unique Foldseek Homologs: 140

Literature

Danchin and Fang [1]: NA
Yang and Tsui [2]: NA
Antczak et al. [3]: pyk; Pyruvate kinase
Zhang et al. [4]: GO:0004743|pyruvate kinase activity
Bianchi et al. [5]: NA

Structures and Sequence Alignment

The best structural homolog that predicted by 1. PBF was Q46078 (Pyruvate kinase) with a FATCAT P-Value: 0 and RMSD of 2.24 angstrom. The sequence alignment identity is 32.5%.
Structural alignment shown in left. Query protein AVX54668.1 colored as red in alignment, homolog Q46078 colored as blue. Query protein AVX54668.1 is also shown in right top, homolog Q46078 showed in right bottom. They are colored based on secondary structures.

  AVX54668.1 MTKETLQKRM-KRTKVITTIGPSTHSAEAIKELFNNGMTTIRLNFSHGSYEEH--GYR-IK-AAKKISKALNKPISIILDTKGPEIRLGKFKDNKQEVV- 94
      Q46078 ---------MDRRTKIVCTLGPAVASADGILRLVEDGMDVARLNFSHGDHPDHEQNYKWVREAAEKTGRA----VGILADLQGPKIRLGRFTDG--ATVW 85

  AVX54668.1 -KGQSITIYTDTYSYLNKECVQG---EMTVAY-DMSVDLKPGDMILIDDGKLELTVDSVEPQ-IIKATAFNHHI----VKTNKRVNLPGIDFSLPFLSEK 184
      Q46078 ENGETIRITVD-------D-VEGTHDRVSTTYKNLAKDAKPGDRLLVDDGKVGLVCVSVEGNDVICEV-----VEGGPVSNNKGVSLPGMDISVPALSEK 172

  AVX54668.1 DEKDILFGCEQGVDYIAASFVNTAENVRQIKEILNKANANHIQIISKIESQVGLDNIDEIIEESDGIMIARGDLGLEIPYYDVPYWEKIIIRKCREKGKI 284
      Q46078 DIRDLRFALKLGVDFIALSFVRSPADAELVHKIMDEE-GRRVPVIAKLEKPEAVTSLEPIVLAFDAVMVARGDLGVEVPLEEVPLVQKRAIQIARENAKP 271

  AVX54668.1 VIVATQMLETMTENPSPTRAEVTDVYFATEL--GADATMLSGESAAG-DYPFLTVHTMSTINKRAEVEFYNKIYYQVQLDNARNSTSGPRAEIADLLAT- 380
      Q46078 VIVATQMLDSMIENSRPTRAEASDV--ANAVLDGADAVMLSGETSVGKD-PHNVVRTMSRI-----VRF------------AE--TDG-R--VPDL--TH 344

  AVX54668.1 --KTKDGEYKY------------AIV-LSKTGELLKTISKFRPNVTILGVSPDKKLWTSFGV-W-HSIFM-NKV-DTLDNLDNNIEK-LSEIA-KSWGAK 459
      Q46078 IPRTKRGVISYSARDIAERLNARALVAFTTSGDTAKRVARLHSHLPLLVFTPNEAVRSELALTWGATTFLCPPVSDT-DDMMREVDRAL--LAMPEYN-K 440

  AVX54668.1 LGEKVLVV--------RSTAIKEIEVI--------- 478
      Q46078 -GDMMVVVAGSPPGVTGNTNMIHVHLLGDDTRIAKL 475

Go Annotations

1. PBF indicates the go terms that are found by both PROST and BLAST and Foldseek.
2. PF indicates the go terms that are found by only PROST and Foldseek.
3. BF indicates the go terms that are found by only BLAST and Foldseek.
4. PB indicates the go terms that are found by both PROST and BLAST.
5. P indicates the go terms that are found by only PROST.
6. F indicates the go terms that are found by only Foldseek.
7. B indicates the go terms that are found by only BLAST.

Source	GO	Description
1. PBF	GO:0004743	pyruvate kinase activity
1. PBF	GO:0016301	kinase activity
1. PBF	GO:1904408	melatonin binding
1. PBF	GO:0006096	glycolytic process
1. PBF	GO:0030955	potassium ion binding
1. PBF	GO:0042866	pyruvate biosynthetic process
1. PBF	GO:0061621	canonical glycolysis
1. PBF	GO:1903672	positive regulation of sprouting angiogenesis
1. PBF	GO:2000767	positive regulation of cytoplasmic translation
1. PBF	GO:0005524	ATP binding
1. PBF	GO:0005791	rough endoplasmic reticulum
1. PBF	GO:0006116	NADH oxidation
1. PBF	GO:0000287	magnesium ion binding
1. PBF	GO:0032869	cellular response to insulin stimulus
1. PBF	GO:0062040	fungal biofilm matrix
1. PBF	GO:2001065	mannan binding
4. PB	GO:0009570	chloroplast stroma
4. PB	GO:0001889	liver development
4. PB	GO:0014870	response to muscle inactivity
4. PB	GO:0005829	cytosol
4. PB	GO:0009408	response to heat
4. PB	GO:0010226	response to lithium ion
4. PB	GO:0001666	response to hypoxia
4. PB	GO:0071872	cellular response to epinephrine stimulus
4. PB	GO:0051591	response to cAMP
4. PB	GO:1902912	pyruvate kinase complex
4. PB	GO:0009629	response to gravity
4. PB	GO:0031639	plasminogen activation
4. PB	GO:0070324	thyroid hormone binding
4. PB	GO:0051707	response to other organism
4. PB	GO:0006754	ATP biosynthetic process
4. PB	GO:0005929	cilium
4. PB	GO:0031100	animal organ regeneration
4. PB	GO:0033198	response to ATP
4. PB	GO:0036180	filamentous growth of a population of unicellular organisms in response to biotic stimulus
4. PB	GO:0030446	hyphal cell wall
4. PB	GO:0030445	yeast-form cell wall
4. PB	GO:0007584	response to nutrient
4. PB	GO:0023026	MHC class II protein complex binding
4. PB	GO:0006090	pyruvate metabolic process
4. PB	GO:0043403	skeletal muscle tissue regeneration
4. PB	GO:0012501	programmed cell death
4. PB	GO:0009749	response to glucose
4. PB	GO:0044416	induction by symbiont of host defense response
4. PB	GO:0010431	seed maturation
4. PB	GO:0036170	filamentous growth of a population of unicellular organisms in response to starvation
4. PB	GO:0003729	mRNA binding
6. F	GO:0008972	phosphomethylpyrimidine kinase activity
6. F	GO:0009228	thiamine biosynthetic process
6. F	GO:0000162	tryptophan biosynthetic process
6. F	GO:0004834	tryptophan synthase activity
6. F	GO:0006084	acetyl-CoA metabolic process
6. F	GO:0004425	indole-3-glycerol-phosphate synthase activity
6. F	GO:0008902	hydroxymethylpyrimidine kinase activity
6. F	GO:1990107	thiazole synthase activity
6. F	GO:0002099	tRNA wobble guanine modification
6. F	GO:0008816	citryl-CoA lyase activity
6. F	GO:0008479	queuine tRNA-ribosyltransferase activity
6. F	GO:0004789	thiamine-phosphate diphosphorylase activity
6. F	GO:0009229	thiamine diphosphate biosynthetic process
6. F	GO:0046872	metal ion binding
6. F	GO:0009346	ATP-independent citrate lyase complex
6. F	GO:0008616	queuosine biosynthetic process
6. F	GO:0101030	tRNA-guanine transglycosylation
6. F	GO:0008815	citrate (pro-3S)-lyase activity
7. B	GO:0046686	response to cadmium ion

Uniprot GO Annotations

GO	Description
GO:0016740	transferase activity
GO:0004743	pyruvate kinase activity
GO:0006096	glycolytic process
GO:0016310	phosphorylation
GO:0030955	potassium ion binding
GO:0005524	ATP binding
GO:0003824	catalytic activity
GO:0046872	metal ion binding
GO:0000287	magnesium ion binding
GO:0000166	nucleotide binding
GO:0016301	kinase activity

Homologs

1. PBF indicates the homologs that are found by both PROST and BLAST and Foldseek.
2. PF indicates the homologs that are found by only PROST and Foldseek.
3. BF indicates the homologs that are found by only BLAST and Foldseek.
4. PB indicates the homologs that are found by both PROST and BLAST.
5. P indicates the homologs that are found by only PROST.
6. F indicates the homologs that are found by only Foldseek.
7. B indicates the homologs that are found by only BLAST.

Source	Homolog	Description	Fatcat Pvalue	PROST Evalue	BLAST Evalue	Foldseek TMScore
1. PBF	B0B7Q0	Pyruvate kinase	0.00e+00	3.29e-38	5.45e-87	0.89
1. PBF	Q8ZYE0	Pyruvate kinase	0.00e+00	1.94e-42	2.63e-48	0.8597
1. PBF	P11979	Pyruvate kinase PKM	0.00e+00	3.29e-25	4.33e-85	0.9084
1. PBF	O94122	Pyruvate kinase	0.00e+00	6.58e-36	6.59e-86	0.9313
1. PBF	Q9Z984	Pyruvate kinase	0.00e+00	2.41e-38	7.93e-80	0.9106
1. PBF	Q44473	Pyruvate kinase	0.00e+00	5.25e-47	6.66e-71	0.8842
1. PBF	O05118	Pyruvate kinase	0.00e+00	8.97e-47	8.43e-78	0.8884
1. PBF	P94939	Pyruvate kinase	0.00e+00	2.65e-45	2.29e-76	0.8906
1. PBF	Q5HF76	Pyruvate kinase	0.00e+00	3.61e-03	7.67e-97	0.8953
1. PBF	P31865	Pyruvate kinase	0.00e+00	1.02e-33	4.82e-87	0.9207
1. PBF	Q8K9M3	Pyruvate kinase	0.00e+00	1.77e-42	3.86e-69	0.9006
1. PBF	Q42954	Pyruvate kinase, cytosolic isozyme	0.00e+00	8.19e-37	2.87e-81	0.9202
1. PBF	Q27686	Pyruvate kinase	0.00e+00	5.27e-42	9.46e-97	0.9147
1. PBF	Q875Z9	Pyruvate kinase	0.00e+00	2.30e-38	3.01e-84	0.9281
1. PBF	B8BJ39	Pyruvate kinase 1, cytosolic	0.00e+00	2.06e-13	3.09e-44	0.8935
1. PBF	O44006	Pyruvate kinase	0.00e+00	1.18e-20	1.35e-89	0.9232
1. PBF	Q875M9	Pyruvate kinase	0.00e+00	7.26e-44	4.07e-90	0.9315
1. PBF	Q89AI8	Pyruvate kinase	0.00e+00	6.92e-44	1.25e-66	0.9058
1. PBF	Q56301	Pyruvate kinase	0.00e+00	5.70e-45	2.26e-63	0.899
1. PBF	Q6FV12	Pyruvate kinase 2	0.00e+00	4.61e-41	4.96e-88	0.9241
1. PBF	P57404	Pyruvate kinase	0.00e+00	1.57e-42	2.33e-65	0.9049
1. PBF	P9WKE4	Pyruvate kinase	0.00e+00	5.02e-46	3.81e-76	0.8987
1. PBF	P22360	Pyruvate kinase	0.00e+00	1.49e-33	2.23e-90	0.915
1. PBF	P55964	Pyruvate kinase isozyme G, chloroplastic (Fragment)	0.00e+00	1.16e-12	3.73e-62	0.903
1. PBF	Q46078	Pyruvate kinase	0.00e+00	1.32e-46	1.07e-76	0.8851
1. PBF	P43924	Pyruvate kinase	0.00e+00	1.49e-45	8.28e-65	0.9025
1. PBF	Q7RVA8	Pyruvate kinase	0.00e+00	1.06e-32	2.57e-89	0.9297
1. PBF	Q40546	Pyruvate kinase isozyme G, chloroplastic	0.00e+00	1.22e-07	3.02e-75	0.9199
1. PBF	B8BM17	Pyruvate kinase 2, cytosolic	0.00e+00	9.22e-16	3.84e-46	0.8805
1. PBF	P11974	Pyruvate kinase PKM	0.00e+00	4.19e-23	3.17e-87	0.9033
1. PBF	Q46289	Pyruvate kinase	0.00e+00	2.36e-43	3.01e-105	0.9274
1. PBF	Q6GG09	Pyruvate kinase	0.00e+00	1.13e-02	2.39e-97	0.9099
1. PBF	P0CE21	Pyruvate kinase	0.00e+00	3.89e-37	1.66e-86	0.8904
1. PBF	Q6G8M9	Pyruvate kinase	0.00e+00	3.61e-03	7.67e-97	0.8887
1. PBF	Q759A9	Pyruvate kinase	0.00e+00	2.62e-40	7.65e-91	0.9245
1. PBF	P77983	Pyruvate kinase I	0.00e+00	7.05e-49	2.84e-105	0.892
1. PBF	Q40545	Pyruvate kinase isozyme A, chloroplastic	0.00e+00	1.27e-02	4.82e-67	0.8288
1. PBF	Q27788	Pyruvate kinase	0.00e+00	1.24e-36	1.47e-85	0.9139
1. PBF	P73534	Pyruvate kinase 2	0.00e+00	2.41e-02	4.07e-86	0.895
1. PBF	Q9YEU2	Pyruvate kinase	0.00e+00	1.38e-45	1.80e-62	0.8791
1. PBF	Q99TG5	Pyruvate kinase	0.00e+00	3.61e-03	7.67e-97	0.8982
1. PBF	P47458	Pyruvate kinase	0.00e+00	2.58e-32	1.95e-110	0.9058
1. PBF	Q7A0N4	Pyruvate kinase	0.00e+00	3.61e-03	7.67e-97	0.8975
1. PBF	Q07637	Pyruvate kinase	0.00e+00	1.69e-38	3.23e-89	0.9083
1. PBF	Q8ZNW0	Pyruvate kinase II	0.00e+00	1.94e-45	2.81e-61	0.8915
1. PBF	P30616	Pyruvate kinase 2	0.00e+00	4.11e-41	8.37e-96	0.9206
1. PBF	P00548	Pyruvate kinase PKM	0.00e+00	5.57e-23	2.81e-84	0.9148
1. PBF	P30614	Pyruvate kinase	0.00e+00	3.04e-32	1.84e-93	0.9291
1. PBF	P0AD62	Pyruvate kinase I	0.00e+00	3.61e-48	2.05e-103	0.9119
1. PBF	Q43117	Pyruvate kinase isozyme A, chloroplastic	0.00e+00	1.31e-05	1.13e-64	0.8444
1. PBF	Q5HNK7	Pyruvate kinase	0.00e+00	2.65e-02	1.87e-95	0.9022
1. PBF	Q6BS75	Pyruvate kinase	0.00e+00	2.00e-43	8.86e-92	0.9189
1. PBF	Q55863	Pyruvate kinase 1	0.00e+00	6.30e-51	6.28e-85	0.9027
1. PBF	Q29536	Pyruvate kinase PKLR	0.00e+00	4.81e-10	2.16e-83	0.9172
1. PBF	Q8Z6K2	Pyruvate kinase I	0.00e+00	8.18e-49	6.74e-105	0.8915
1. PBF	Q7A559	Pyruvate kinase	0.00e+00	3.61e-03	7.67e-97	0.8923
1. PBF	P70789	Pyruvate kinase	0.00e+00	1.60e-45	3.94e-82	0.8792
1. PBF	Q2FG40	Pyruvate kinase	0.00e+00	3.61e-03	7.67e-97	0.8987
1. PBF	Q8FP04	Pyruvate kinase	0.00e+00	1.23e-45	9.20e-79	0.8829
1. PBF	Q2YTE3	Pyruvate kinase	0.00e+00	4.81e-03	9.30e-97	0.8987
1. PBF	Q6FIS9	Pyruvate kinase 1	0.00e+00	2.68e-37	5.42e-86	0.9292
1. PBF	Q5NVN0	Pyruvate kinase PKM	0.00e+00	9.05e-25	1.62e-84	0.9047
1. PBF	Q8SQP0	Pyruvate kinase	0.00e+00	8.55e-45	1.38e-68	0.9176
1. PBF	O08309	Pyruvate kinase	0.00e+00	1.25e-44	4.31e-115	0.9179
1. PBF	Q92122	Pyruvate kinase PKM	0.00e+00	1.06e-21	1.87e-85	0.907
1. PBF	Q9WY51	Pyruvate kinase	0.00e+00	6.78e-43	8.32e-69	0.8879
1. PBF	Q875S4	Pyruvate kinase	0.00e+00	2.37e-46	3.31e-89	0.9334
1. PBF	P78031	Pyruvate kinase	0.00e+00	2.52e-38	9.29e-115	0.9022
1. PBF	Q8CS69	Pyruvate kinase	0.00e+00	2.65e-02	1.87e-95	0.9003
1. PBF	P30615	Pyruvate kinase 1	0.00e+00	1.97e-41	1.13e-97	0.9207
1. PBF	P22200	Pyruvate kinase, cytosolic isozyme	0.00e+00	3.50e-34	9.63e-88	0.9182
1. PBF	O51323	Pyruvate kinase	0.00e+00	2.39e-34	3.61e-71	0.8682
1. PBF	Q12669	Pyruvate kinase	0.00e+00	1.67e-34	2.06e-92	0.9186
1. PBF	Q9PK61	Pyruvate kinase	0.00e+00	6.64e-42	2.83e-89	0.889
1. PBF	Q49YC7	Pyruvate kinase	0.00e+00	1.06e-02	5.22e-96	0.9057
1. PBF	P32044	Pyruvate kinase	0.00e+00	6.92e-05	2.17e-72	0.8172
3. BF	P80885	Pyruvate kinase	0.00e+00	NA	1.93e-102	0.9022
3. BF	Q4L739	Pyruvate kinase	0.00e+00	NA	1.94e-97	0.8995
3. BF	Q02499	Pyruvate kinase	0.00e+00	NA	1.19e-97	0.9027
3. BF	P34038	Pyruvate kinase	0.00e+00	NA	3.84e-99	0.8971
3. BF	P51182	Pyruvate kinase	0.00e+00	NA	1.06e-101	0.9067
3. BF	P51181	Pyruvate kinase	0.00e+00	NA	7.14e-103	0.905
3. BF	P19680	Pyruvate kinase (Fragment)	1.37e-02	NA	6.64e-27	0.8517
3. BF	Q04668	Pyruvate kinase (Fragment)	5.34e-05	NA	9.74e-16	0.9644
4. PB	Q2RAK2	Pyruvate kinase 1, cytosolic	0.00e+00	2.06e-13	3.09e-44	NA
4. PB	P52489	Pyruvate kinase 2	0.00e+00	3.68e-39	2.58e-88	NA
4. PB	P11980	Pyruvate kinase PKM	0.00e+00	3.13e-24	8.38e-86	NA
4. PB	P30613	Pyruvate kinase PKLR	0.00e+00	2.81e-08	1.26e-83	NA
4. PB	P53657	Pyruvate kinase PKLR	0.00e+00	3.52e-11	1.52e-77	NA
4. PB	O65595	Probable pyruvate kinase, cytosolic isozyme	0.00e+00	9.16e-33	7.61e-84	NA
4. PB	P21599	Pyruvate kinase II	0.00e+00	3.98e-45	4.48e-62	NA
4. PB	P00549	Pyruvate kinase 1	0.00e+00	8.63e-39	6.50e-87	NA
4. PB	Q54RF5	Pyruvate kinase	0.00e+00	9.51e-38	2.12e-94	NA
4. PB	P14618	Pyruvate kinase PKM	0.00e+00	3.76e-23	3.93e-84	NA
4. PB	O62619	Pyruvate kinase	0.00e+00	9.10e-22	6.21e-84	NA
4. PB	P52480	Pyruvate kinase PKM	0.00e+00	2.93e-23	6.99e-84	NA
4. PB	Q2FXM9	Pyruvate kinase	0.00e+00	3.61e-03	7.67e-97	NA
4. PB	P0AD61	Pyruvate kinase I	0.00e+00	3.61e-48	2.05e-103	NA
4. PB	P46614	Pyruvate kinase	0.00e+00	5.41e-41	7.86e-89	NA
4. PB	Q9FLW9	Plastidial pyruvate kinase 2	0.00e+00	8.99e-04	2.23e-76	NA
4. PB	Q57572	Pyruvate kinase	0.00e+00	4.16e-33	7.69e-57	NA
4. PB	Q2QXR8	Pyruvate kinase 2, cytosolic	0.00e+00	9.22e-16	3.84e-46	NA
4. PB	Q42806	Pyruvate kinase, cytosolic isozyme	0.00e+00	9.30e-36	8.69e-86	NA
4. PB	P12928	Pyruvate kinase PKLR	0.00e+00	5.54e-10	1.91e-79	NA
4. PB	Q93Z53	Plastidial pyruvate kinase 3, chloroplastic	0.00e+00	1.56e-05	2.71e-75	NA
4. PB	Q10208	Pyruvate kinase	0.00e+00	1.37e-35	8.93e-87	NA
4. PB	P9WKE5	Pyruvate kinase	0.00e+00	5.02e-46	3.81e-76	NA
6. F	Q5LCA6	Thiazole synthase	1.02e-06	NA	NA	0.5712
6. F	P66982	Tryptophan synthase alpha chain	3.56e-03	NA	NA	0.5783
6. F	Q14HA0	Queuine tRNA-ribosyltransferase	8.98e-03	NA	NA	0.3597
6. F	Q8GAA6	Queuine tRNA-ribosyltransferase	3.20e-02	NA	NA	0.38
6. F	Q2RHX4	Thiazole synthase	1.92e-03	NA	NA	0.6055
6. F	Q21KW1	Queuine tRNA-ribosyltransferase	8.65e-03	NA	NA	0.3437
6. F	Q7TTX7	Queuine tRNA-ribosyltransferase	2.51e-02	NA	NA	0.3864
6. F	B0KN58	Thiazole synthase	3.82e-03	NA	NA	0.4231
6. F	A6UYJ0	Thiazole synthase	3.00e-03	NA	NA	0.4064
6. F	B2SHD4	Queuine tRNA-ribosyltransferase	8.76e-03	NA	NA	0.3659
6. F	A6M1W6	Thiamine-phosphate synthase	2.77e-03	NA	NA	0.6868
6. F	Q5V0G6	Thiamine-phosphate synthase	4.77e-03	NA	NA	0.7001
6. F	A6QGS5	Tryptophan synthase alpha chain	5.38e-03	NA	NA	0.5452
6. F	Q48A93	Thiazole synthase	2.61e-07	NA	NA	0.5343
6. F	Q74FL9	Thiazole synthase	3.33e-03	NA	NA	0.4122
6. F	C6E0C4	Thiazole synthase	2.51e-03	NA	NA	0.3995
6. F	A2CCL1	Queuine tRNA-ribosyltransferase	3.68e-02	NA	NA	0.3905
6. F	Q6DAM4	Thiazole synthase	1.22e-02	NA	NA	0.423
6. F	B4EYU5	Thiazole synthase	5.49e-03	NA	NA	0.4239
6. F	B2U764	Thiazole synthase	1.08e-02	NA	NA	0.5001
6. F	Q7NMG4	Queuine tRNA-ribosyltransferase	6.82e-02	NA	NA	0.3841
6. F	Q2FH63	Tryptophan synthase alpha chain	5.33e-03	NA	NA	0.5471
6. F	Q9X1P7	Queuine tRNA-ribosyltransferase	1.10e-02	NA	NA	0.3862
6. F	Q72TL3	Queuine tRNA-ribosyltransferase	4.30e-03	NA	NA	0.3655
6. F	A6TGP7	Thiazole synthase	1.17e-06	NA	NA	0.4335
6. F	Q476U3	Thiazole synthase	1.25e-02	NA	NA	0.5362
6. F	Q5LWJ1	Thiazole synthase	8.33e-07	NA	NA	0.5883
6. F	A5USQ4	Indole-3-glycerol phosphate synthase	1.51e-02	NA	NA	0.5798
6. F	B7LA84	Thiazole synthase	1.53e-06	NA	NA	0.4636
6. F	C6DB26	Queuine tRNA-ribosyltransferase	4.98e-03	NA	NA	0.4101
6. F	Q6LVX7	Thiazole synthase	1.41e-06	NA	NA	0.4024
6. F	Q9I6B4	Thiazole synthase	1.93e-03	NA	NA	0.407
6. F	Q5KY94	3-dehydroquinate dehydratase	2.55e-03	NA	NA	0.464
6. F	B7V3W7	Thiazole synthase	1.94e-03	NA	NA	0.3988
6. F	Q6G9I6	Tryptophan synthase alpha chain	4.39e-03	NA	NA	0.575
6. F	A9WDL8	Thiamine-phosphate synthase	1.23e-02	NA	NA	0.6685
6. F	B0K959	Queuine tRNA-ribosyltransferase	7.67e-03	NA	NA	0.3463
6. F	B4EU13	Queuine tRNA-ribosyltransferase	4.02e-03	NA	NA	0.4295
6. F	Q5WHR2	Queuine tRNA-ribosyltransferase	3.48e-03	NA	NA	0.377
6. F	Q87S36	Queuine tRNA-ribosyltransferase	3.54e-03	NA	NA	0.3616
6. F	A5F3H2	Queuine tRNA-ribosyltransferase	3.84e-03	NA	NA	0.3655
6. F	Q6D855	Queuine tRNA-ribosyltransferase	5.16e-03	NA	NA	0.4407
6. F	C3K3L7	Thiazole synthase	1.47e-03	NA	NA	0.4173
6. F	Q8CPB0	Tryptophan synthase alpha chain	7.72e-03	NA	NA	0.5735
6. F	A3CS45	Thiamine-phosphate synthase	2.68e-06	NA	NA	0.6945
6. F	Q7TUM6	Queuine tRNA-ribosyltransferase	3.54e-02	NA	NA	0.3815
6. F	Q3AN18	Queuine tRNA-ribosyltransferase	2.30e-02	NA	NA	0.3783
6. F	C6DHS2	Thiazole synthase	1.31e-02	NA	NA	0.4244
6. F	B1KHI0	Thiazole synthase	1.24e-03	NA	NA	0.403
6. F	Q5PK87	Thiazole synthase	1.20e-06	NA	NA	0.4218
6. F	C5BV85	Indole-3-glycerol phosphate synthase	7.07e-03	NA	NA	0.6032
6. F	A0KV50	Queuine tRNA-ribosyltransferase	3.21e-03	NA	NA	0.3978
6. F	A5UUL3	Thiamine-phosphate synthase	2.21e-03	NA	NA	0.6661
6. F	Q64TA0	Thiazole synthase	1.07e-06	NA	NA	0.5715
6. F	Q31FZ5	Queuine tRNA-ribosyltransferase	5.68e-03	NA	NA	0.3784
6. F	B7VJR8	Queuine tRNA-ribosyltransferase	5.79e-03	NA	NA	0.3877
6. F	Q8XS01	Indole-3-glycerol phosphate synthase 2	9.01e-03	NA	NA	0.5803
6. F	B5YHX4	Queuine tRNA-ribosyltransferase	1.26e-02	NA	NA	0.3809
6. F	Q8R806	Thiamine-phosphate synthase	4.52e-03	NA	NA	0.6616
6. F	A3PAZ2	Queuine tRNA-ribosyltransferase	3.32e-02	NA	NA	0.3652
6. F	O19915	Thiazole synthase	1.20e-04	NA	NA	0.4238
6. F	A5USV3	Queuine tRNA-ribosyltransferase	3.97e-02	NA	NA	0.3583
6. F	Q8FTH8	Thiamine biosynthesis multifunctional protein ThiED	5.70e-03	NA	NA	0.35
6. F	A5WGS6	Queuine tRNA-ribosyltransferase	1.13e-02	NA	NA	0.357
6. F	Q8Y372	Thiazole synthase	1.09e-02	NA	NA	0.5047
6. F	B1JJK2	Thiazole synthase	3.03e-03	NA	NA	0.4209
6. F	A6U1J5	Tryptophan synthase alpha chain	3.70e-03	NA	NA	0.5794
6. F	Q5HPG9	Tryptophan synthase alpha chain	7.65e-03	NA	NA	0.5726
6. F	Q9KVS4	Thiazole synthase	1.37e-03	NA	NA	0.599
6. F	A8H2K8	Queuine tRNA-ribosyltransferase	4.65e-03	NA	NA	0.3908
6. F	Q5M2K9	Queuine tRNA-ribosyltransferase	6.99e-03	NA	NA	0.3668
6. F	Q9JXF5	Thiazole synthase	1.29e-02	NA	NA	0.5822
6. F	O53078	Citrate lyase subunit beta	5.77e-06	NA	NA	0.5447
6. F	Q2GDS9	Thiazole synthase	3.58e-03	NA	NA	0.4144
6. F	Q6MD31	Queuine tRNA-ribosyltransferase	3.10e-02	NA	NA	0.3765
6. F	Q5HG46	Tryptophan synthase alpha chain	4.25e-03	NA	NA	0.5737
6. F	A7MQQ2	Thiazole synthase	9.36e-07	NA	NA	0.6096
6. F	Q6GH35	Indole-3-glycerol phosphate synthase	5.81e-02	NA	NA	0.5741
6. F	Q0IDF3	Queuine tRNA-ribosyltransferase	2.05e-02	NA	NA	0.3651
6. F	P17725	Citrate lyase subunit beta	2.01e-04	NA	NA	0.5461
6. F	B8F3W0	Queuine tRNA-ribosyltransferase	1.64e-02	NA	NA	0.3971
6. F	Q4QNU3	Queuine tRNA-ribosyltransferase	4.01e-03	NA	NA	0.3939
6. F	Q9L9J1	Thiazole synthase	1.38e-06	NA	NA	0.4191
6. F	A0Q6X1	Queuine tRNA-ribosyltransferase	8.82e-03	NA	NA	0.3596
6. F	Q8NWU3	Indole-3-glycerol phosphate synthase	5.82e-02	NA	NA	0.5573
6. F	Q31CR1	Queuine tRNA-ribosyltransferase	2.33e-02	NA	NA	0.3758
6. F	A7GHT6	Queuine tRNA-ribosyltransferase	4.28e-03	NA	NA	0.4132
6. F	A8FXC6	Queuine tRNA-ribosyltransferase	3.40e-03	NA	NA	0.3528
6. F	Q0SSM0	Thiazole synthase	4.13e-03	NA	NA	0.417
6. F	Q8NQH1	Thiamine biosynthesis multifunctional protein ThiED	7.41e-03	NA	NA	0.3563
6. F	A1SL44	Indole-3-glycerol phosphate synthase	1.14e-02	NA	NA	0.5877
6. F	A5F4E2	Thiazole synthase	1.34e-03	NA	NA	0.4282
6. F	Q8CXS3	Queuine tRNA-ribosyltransferase	8.30e-03	NA	NA	0.3655
6. F	Q55983	Queuine tRNA-ribosyltransferase	1.05e-02	NA	NA	0.3802
6. F	Q9PGT5	Indole-3-glycerol phosphate synthase	1.65e-02	NA	NA	0.5663
6. F	Q8ZAP9	Thiazole synthase	2.28e-03	NA	NA	0.4202
6. F	B8HX02	Queuine tRNA-ribosyltransferase	1.48e-02	NA	NA	0.3317
6. F	P57831	Queuine tRNA-ribosyltransferase	5.34e-03	NA	NA	0.375
6. F	Q18GX9	Thiamine-phosphate synthase	4.35e-07	NA	NA	0.6928
6. F	Q03ER2	Queuine tRNA-ribosyltransferase	7.05e-03	NA	NA	0.3706
6. F	A2BP70	Queuine tRNA-ribosyltransferase	2.29e-02	NA	NA	0.3875
6. F	Q3B088	Queuine tRNA-ribosyltransferase	2.16e-02	NA	NA	0.3825
6. F	Q82A84	Indole-3-glycerol phosphate synthase	5.53e-03	NA	NA	0.5907
6. F	B0TND4	Queuine tRNA-ribosyltransferase	3.46e-03	NA	NA	0.3703
6. F	A5ISQ5	Tryptophan synthase alpha chain	4.20e-03	NA	NA	0.5825
6. F	A2BSL8	Indole-3-glycerol phosphate synthase	1.11e-02	NA	NA	0.5569
6. F	B5ED95	Thiazole synthase	2.73e-03	NA	NA	0.4109
6. F	C3LSZ4	Queuine tRNA-ribosyltransferase	3.97e-03	NA	NA	0.3599
6. F	P66983	Tryptophan synthase alpha chain	3.81e-03	NA	NA	0.5721
6. F	Q87JW8	Thiamine-phosphate synthase	2.51e-03	NA	NA	0.728
6. F	A4FLL0	Indole-3-glycerol phosphate synthase	1.07e-02	NA	NA	0.5982
6. F	C0Q2S2	Thiazole synthase	1.31e-06	NA	NA	0.4111
6. F	Q5L6R5	Thiamine-phosphate synthase	2.59e-04	NA	NA	0.7251
6. F	A5G7P4	Thiazole synthase	1.99e-03	NA	NA	0.4089
6. F	Q2YXZ6	Tryptophan synthase alpha chain	4.37e-03	NA	NA	0.5761
6. F	Q0W1L8	Thiamine-phosphate synthase	2.26e-06	NA	NA	0.6858
6. F	Q7VQB1	Queuine tRNA-ribosyltransferase	5.40e-03	NA	NA	0.3634
6. F	Q8DEY0	Queuine tRNA-ribosyltransferase	4.82e-03	NA	NA	0.3608
6. F	Q88V05	Queuine tRNA-ribosyltransferase	6.86e-03	NA	NA	0.388
6. F	Q7MNH1	Queuine tRNA-ribosyltransferase	5.99e-03	NA	NA	0.3601
6. F	A7IA09	Thiamine-phosphate synthase	1.06e-06	NA	NA	0.7086
6. F	B8CLC5	Queuine tRNA-ribosyltransferase	3.50e-03	NA	NA	0.3784
6. F	C1DCM3	Thiamine-phosphate synthase	2.39e-03	NA	NA	0.6918
6. F	Q4L680	Tryptophan synthase alpha chain	3.56e-03	NA	NA	0.5473
6. F	B0TYY3	Queuine tRNA-ribosyltransferase	6.81e-03	NA	NA	0.3591
6. F	Q7VDR5	Queuine tRNA-ribosyltransferase	2.17e-02	NA	NA	0.3502
6. F	Q081M2	Thiazole synthase	1.66e-03	NA	NA	0.4083
6. F	Q0RFX9	Indole-3-glycerol phosphate synthase	1.68e-02	NA	NA	0.5417
6. F	A7X240	Tryptophan synthase alpha chain	3.59e-03	NA	NA	0.5788
6. F	Q824E9	Thiamine-phosphate synthase	2.29e-06	NA	NA	0.7086
6. F	A9BDP3	Queuine tRNA-ribosyltransferase	2.04e-02	NA	NA	0.368
6. F	B9E9B4	Thiazole synthase	1.68e-03	NA	NA	0.4048
6. F	A8G2T1	Queuine tRNA-ribosyltransferase	3.14e-02	NA	NA	0.3582
6. F	Q02U32	Thiazole synthase	2.33e-03	NA	NA	0.4039
6. F	B1IMF1	Queuine tRNA-ribosyltransferase	4.33e-03	NA	NA	0.3901
6. F	A4W5B3	Thiazole synthase	1.33e-03	NA	NA	0.4339
6. F	B9DP27	Tryptophan synthase alpha chain	4.06e-03	NA	NA	0.5607
6. F	A1T8X3	Indole-3-glycerol phosphate synthase	1.86e-02	NA	NA	0.5998
6. F	Q609Z5	Thiazole synthase	2.34e-03	NA	NA	0.3945
6. F	B8I3J4	Thiamine-phosphate synthase	4.99e-03	NA	NA	0.6895
7. B	Q9LIK0	Plastidial pyruvate kinase 1, chloroplastic	0.00e+00	NA	9.52e-66	NA
7. B	O30853	Pyruvate kinase I (Fragment)	1.11e-16	NA	1.98e-31	NA
7. B	Q9M3B6	Plastidial pyruvate kinase 4, chloroplastic	8.23e-09	NA	3.46e-18	NA