Summary
The literature section presents previous knowledge about this protein. There have been five different efforts to annotate minimal organism genome. The annotations from those efforts are given in the Literature section for completeness.
AVX54670.1
JCVISYN3A_0227
Branched-chain alpha-keto acid dehydrogenase subunit E2.
M. mycoides homolog: Q6MTX8.
TIGRfam Classification: 4=Probable.
Category: Nonessential.
Statistics
Total GO Annotation: 71
Unique PROST Go: 5
Unique BLAST Go: 20
Unique Foldseek Go: 1
Total Homologs: 145
Unique PROST Homologs: 1
Unique BLAST Homologs: 27
Unique Foldseek Homologs: 4
Structures and Sequence Alignment
The best structural homolog that predicted by 1. PBF was
Q9I3D2
(Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex) with a FATCAT P-Value: 0 and RMSD of 1.57 angstrom. The sequence alignment identity is 32.1%.
Structural alignment shown in left. Query protein AVX54670.1 colored as red in alignment, homolog Q9I3D2 colored as blue.
Query protein AVX54670.1 is also shown in right top, homolog Q9I3D2 showed in right bottom. They are colored based on secondary structures.
AVX54670.1 M-FKVKFADIGEGLTEGTVAEVLVKVGDVVKEGQSLYFVETDKVNSEIPAPVAGKIAVINIKAGQEIKVGDVVM------EIDEGSGASVASEPKAEAKQ 93 Q9I3D2 MAIEIKAPTFPESVADGTVATWHKKPGEAVKRDELIVDIETDKVVIEVLAEADGVLAEI-IK--NE---GDTVLSNELLGKLNEG-GAAAPAAPAAAAPA 93 AVX54670.1 EAKVEVVEENASVVGATPVSNDLIVRKQASTVTKSSTIKATPLARKVAADLNIDLSLVTPTGPNQRILVADIKNYHSSSAQPASQPAPTPTLVASQPAPA 193 Q9I3D2 AAPAAQAAAPAAAGG-----DDAIL---------------SPAARKLAEEAGIDPNSIAGTGKGGRVTKEDV-----VAAVEAKKNAPA--------APA 160 AVX54670.1 PTPAITPAIKVVEPSAPL--SWD----EVPMNGVRKATVKAMTKSHTEIAAFT-----GMKN-TDITETHKMRTEL--KDHAAASGIKLTYLAFIIKAVA 279 Q9I3D2 -KPA-APA---AE--APIFAAGDRVEKRVPMTRLRAKVAERLVEAQSAMAMLTTFNEVNMKPIMDLRSKYK---DLFEKKH---NGVRLGFMSFFVKAAT 247 AVX54670.1 KSLRDMPNINVRGDFANNKIQFMHNIN-IGIAVDTPNGLMVPVIKGADHLSVFEIAIKISELANKAKDGKLTRAEMTEATFTVSN---FGSVGLDYATPI 375 Q9I3D2 EALKRFPGVNASID--GNDIVY-HGYQDIGVAVSSDRGLVVPVLRNAEFMSLAEIEGGIANFGKKAKEGKLTIEDMTGGTFTISNGGVFGSL-L--STPI 341 AVX54670.1 INSPESAILGVGTMSQTPLYINGELQKRFIMP---LSMTCDHRIIDGADAGRFLIKVQDYLSKP--VLLFM 441 Q9I3D2 VNPPQTAILGMHKIQERPMAVNGQV---VILPMMYLALSYDHRLIDGKEAVSFLVAIKDLLEDPARLLLDV 409
Go Annotations
1. PBF indicates the go terms that are found by both PROST and BLAST and Foldseek.
2. PF indicates the go terms that are found by only PROST and Foldseek.
3. BF indicates the go terms that are found by only BLAST and Foldseek.
4. PB indicates the go terms that are found by both PROST and BLAST.
5. P indicates the go terms that are found by only PROST.
6. F indicates the go terms that are found by only Foldseek.
7. B indicates the go terms that are found by only BLAST.
| Source | GO | Description |
|---|---|---|
| 1. PBF | GO:0004742 | dihydrolipoyllysine-residue acetyltransferase activity |
| 1. PBF | GO:0006103 | 2-oxoglutarate metabolic process |
| 1. PBF | GO:0005759 | mitochondrial matrix |
| 1. PBF | GO:0004149 | dihydrolipoyllysine-residue succinyltransferase activity |
| 1. PBF | GO:0034604 | pyruvate dehydrogenase (NAD+) activity |
| 1. PBF | GO:0006104 | succinyl-CoA metabolic process |
| 1. PBF | GO:0016209 | antioxidant activity |
| 1. PBF | GO:0106077 | histone succinylation |
| 1. PBF | GO:0033512 | L-lysine catabolic process to acetyl-CoA via saccharopine |
| 1. PBF | GO:0005967 | mitochondrial pyruvate dehydrogenase complex |
| 1. PBF | GO:0016746 | acyltransferase activity |
| 1. PBF | GO:0045150 | acetoin catabolic process |
| 1. PBF | GO:0006099 | tricarboxylic acid cycle |
| 1. PBF | GO:0045252 | oxoglutarate dehydrogenase complex |
| 1. PBF | GO:0016407 | acetyltransferase activity |
| 1. PBF | GO:0006096 | glycolytic process |
| 1. PBF | GO:0045254 | pyruvate dehydrogenase complex |
| 1. PBF | GO:0031405 | lipoic acid binding |
| 1. PBF | GO:0043754 | dihydrolipoyllysine-residue (2-methylpropanoyl)transferase activity |
| 1. PBF | GO:0006086 | acetyl-CoA biosynthetic process from pyruvate |
| 3. BF | GO:0030976 | thiamine pyrophosphate binding |
| 3. BF | GO:0050439 | 2-hydroxy-3-oxoadipate synthase activity |
| 3. BF | GO:0008683 | 2-oxoglutarate decarboxylase activity |
| 3. BF | GO:0004591 | oxoglutarate dehydrogenase (succinyl-transferring) activity |
| 4. PB | GO:0045723 | positive regulation of fatty acid biosynthetic process |
| 4. PB | GO:0043209 | myelin sheath |
| 4. PB | GO:0009534 | chloroplast thylakoid |
| 4. PB | GO:0022626 | cytosolic ribosome |
| 4. PB | GO:0042645 | mitochondrial nucleoid |
| 4. PB | GO:0005739 | mitochondrion |
| 4. PB | GO:0043617 | cellular response to sucrose starvation |
| 4. PB | GO:0005947 | mitochondrial alpha-ketoglutarate dehydrogenase complex |
| 4. PB | GO:0006734 | NADH metabolic process |
| 4. PB | GO:1901046 | positive regulation of oviposition |
| 4. PB | GO:0009353 | mitochondrial oxoglutarate dehydrogenase complex |
| 4. PB | GO:0061732 | mitochondrial acetyl-CoA biosynthetic process from pyruvate |
| 4. PB | GO:0061063 | positive regulation of nematode larval development |
| 4. PB | GO:0031625 | ubiquitin protein ligase binding |
| 4. PB | GO:0009646 | response to absence of light |
| 4. PB | GO:0006006 | glucose metabolic process |
| 4. PB | GO:0009941 | chloroplast envelope |
| 4. PB | GO:0004147 | dihydrolipoamide branched chain acyltransferase activity |
| 4. PB | GO:0034451 | centriolar satellite |
| 4. PB | GO:0015630 | microtubule cytoskeleton |
| 4. PB | GO:0030431 | sleep |
| 5. P | GO:0040019 | positive regulation of embryonic development |
| 5. P | GO:0015036 | disulfide oxidoreductase activity |
| 5. P | GO:0004148 | dihydrolipoyl dehydrogenase activity |
| 5. P | GO:0043231 | intracellular membrane-bounded organelle |
| 5. P | GO:0009744 | response to sucrose |
| 6. F | GO:0004739 | pyruvate dehydrogenase (acetyl-transferring) activity |
| 7. B | GO:0019899 | enzyme binding |
| 7. B | GO:0004658 | propionyl-CoA carboxylase activity |
| 7. B | GO:0003989 | acetyl-CoA carboxylase activity |
| 7. B | GO:0034029 | 2-oxoglutarate carboxylase activity |
| 7. B | GO:0006633 | fatty acid biosynthetic process |
| 7. B | GO:0047154 | methylmalonyl-CoA carboxytransferase activity |
| 7. B | GO:0019541 | propionate metabolic process |
| 7. B | GO:0019626 | short-chain fatty acid catabolic process |
| 7. B | GO:0016042 | lipid catabolic process |
| 7. B | GO:0005737 | cytoplasm |
| 7. B | GO:0015451 | decarboxylation-driven active transmembrane transporter activity |
| 7. B | GO:0006090 | pyruvate metabolic process |
| 7. B | GO:0009062 | fatty acid catabolic process |
| 7. B | GO:0009374 | biotin binding |
| 7. B | GO:0006814 | sodium ion transport |
| 7. B | GO:0016624 | oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor |
| 7. B | GO:0008948 | oxaloacetate decarboxylase activity |
| 7. B | GO:0004736 | pyruvate carboxylase activity |
| 7. B | GO:0016421 | CoA carboxylase activity |
| 7. B | GO:0009317 | acetyl-CoA carboxylase complex |
Uniprot GO Annotations
| GO | Description |
|---|---|
| GO:0016740 | transferase activity |
| GO:0016746 | acyltransferase activity |
Homologs
1. PBF indicates the homologs that are found by both PROST and BLAST and Foldseek.
2. PF indicates the homologs that are found by only PROST and Foldseek.
3. BF indicates the homologs that are found by only BLAST and Foldseek.
4. PB indicates the homologs that are found by both PROST and BLAST.
5. P indicates the homologs that are found by only PROST.
6. F indicates the homologs that are found by only Foldseek.
7. B indicates the homologs that are found by only BLAST.
| Source | Homolog | Description | Fatcat Pvalue | PROST Evalue | BLAST Evalue | Foldseek TMScore |
|---|---|---|---|---|---|---|
| 1. PBF | P75392 | Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex | 1.18e-12 | 3.22e-48 | 2.80e-14 | 0.5973 |
| 1. PBF | Q5HG07 | Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex | 2.27e-12 | 1.12e-54 | 1.27e-46 | 0.6774 |
| 1. PBF | P10802 | Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex | 1.35e-12 | 5.04e-18 | 1.11e-52 | 0.6116 |
| 1. PBF | Q8CT13 | Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex | 0.00e+00 | 4.55e-70 | 2.41e-77 | 0.5254 |
| 1. PBF | P22439 | Pyruvate dehydrogenase protein X component | 2.11e-13 | 2.18e-16 | 2.95e-33 | 0.5868 |
| 1. PBF | Q6GGZ6 | Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex | 2.05e-14 | 6.49e-56 | 2.93e-46 | 0.676 |
| 1. PBF | Q9N0F1 | Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial | 9.70e-13 | 4.61e-12 | 2.47e-34 | 0.5737 |
| 1. PBF | Q5HGY9 | Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex | 0.00e+00 | 5.47e-70 | 7.14e-78 | 0.5258 |
| 1. PBF | P57389 | Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex | 8.90e-12 | 3.08e-46 | 1.52e-36 | 0.6385 |
| 1. PBF | P37942 | Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex | 1.89e-15 | 3.97e-59 | 3.15e-64 | 0.6689 |
| 1. PBF | P45118 | Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex | 3.66e-15 | 1.69e-31 | 2.55e-46 | 0.5724 |
| 1. PBF | P20285 | Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial | 0.00e+00 | 1.54e-27 | 1.27e-25 | 0.5926 |
| 1. PBF | P47514 | Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex | 0.00e+00 | 2.04e-47 | 3.78e-50 | 0.5847 |
| 1. PBF | P09062 | Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex | 3.06e-14 | 9.80e-59 | 3.04e-65 | 0.6348 |
| 1. PBF | P65636 | Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex | 0.00e+00 | 3.56e-70 | 9.33e-78 | 0.5364 |
| 1. PBF | P0AFG7 | Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex | 0.00e+00 | 1.05e-44 | 7.24e-46 | 0.6454 |
| 1. PBF | Q7A5N4 | Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex | 5.88e-15 | 1.16e-55 | 2.65e-47 | 0.6789 |
| 1. PBF | Q5HQ74 | Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex | 0.00e+00 | 1.46e-69 | 9.44e-76 | 0.523 |
| 1. PBF | Q1RJT3 | Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex | 5.83e-12 | 3.16e-52 | 3.63e-44 | 0.6412 |
| 1. PBF | Q4L6C3 | Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex | 1.64e-08 | 5.68e-52 | 1.14e-45 | 0.6719 |
| 1. PBF | P11961 | Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex | 4.69e-14 | 1.18e-69 | 5.92e-67 | 0.6856 |
| 1. PBF | Q99U75 | Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex | 1.11e-16 | 1.16e-55 | 2.65e-47 | 0.6761 |
| 1. PBF | Q59821 | Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex | 0.00e+00 | 1.34e-68 | 1.42e-77 | 0.5253 |
| 1. PBF | Q92HK7 | Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex | 6.66e-16 | 2.37e-50 | 2.10e-46 | 0.6722 |
| 1. PBF | P21883 | Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex | 2.69e-13 | 1.99e-70 | 2.87e-75 | 0.6502 |
| 1. PBF | P20708 | Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex | 1.11e-15 | 8.81e-42 | 1.84e-40 | 0.632 |
| 1. PBF | P11179 | Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial | 7.30e-12 | 1.37e-12 | 1.68e-36 | 0.5773 |
| 1. PBF | P35489 | Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex | 1.41e-14 | 3.04e-25 | 5.81e-89 | 0.6519 |
| 1. PBF | P65634 | Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex | 1.11e-13 | 2.70e-31 | 6.04e-29 | 0.5307 |
| 1. PBF | Q59638 | Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex | 7.85e-12 | 3.62e-28 | 6.31e-50 | 0.6439 |
| 1. PBF | Q49XM4 | Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex | 3.15e-11 | 2.84e-56 | 1.07e-50 | 0.6743 |
| 1. PBF | Q68WK6 | Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex | 0.00e+00 | 8.26e-47 | 3.45e-43 | 0.7077 |
| 1. PBF | Q92J43 | Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex | 0.00e+00 | 4.56e-43 | 5.27e-50 | 0.6621 |
| 1. PBF | Q8CSL9 | Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex | 2.51e-11 | 1.44e-50 | 1.19e-50 | 0.6764 |
| 1. PBF | Q4UKI7 | Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex | 0.00e+00 | 1.62e-47 | 5.12e-50 | 0.6543 |
| 1. PBF | Q9ZDY4 | Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex | 1.48e-12 | 5.19e-50 | 8.07e-49 | 0.6362 |
| 1. PBF | Q68XI8 | Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex | 0.00e+00 | 9.03e-43 | 6.87e-48 | 0.6701 |
| 1. PBF | Q9I3D2 | Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex | 0.00e+00 | 8.58e-41 | 1.69e-39 | 0.6095 |
| 1. PBF | Q8K9T8 | Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex | 0.00e+00 | 2.06e-44 | 2.22e-59 | 0.556 |
| 1. PBF | Q4ULG1 | Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex | 1.11e-16 | 1.05e-49 | 2.92e-46 | 0.6768 |
| 1. PBF | Q6FYD4 | Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex | 0.00e+00 | 2.60e-45 | 4.47e-56 | 0.6125 |
| 1. PBF | Q2FH26 | Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex | 2.61e-10 | 1.12e-54 | 1.27e-46 | 0.6757 |
| 1. PBF | Q8NWR7 | Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex | 2.22e-16 | 1.12e-54 | 1.27e-46 | 0.6786 |
| 1. PBF | Q90512 | Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial (Fragment) | 7.09e-12 | 3.65e-23 | 1.43e-39 | 0.5507 |
| 1. PBF | Q8GCY1 | Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex | 1.11e-16 | 4.47e-52 | 7.10e-51 | 0.6433 |
| 1. PBF | Q6G9E9 | Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex | 2.17e-12 | 1.12e-54 | 1.27e-46 | 0.6748 |
| 1. PBF | P45302 | Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex | 0.00e+00 | 3.37e-44 | 2.03e-46 | 0.6546 |
| 1. PBF | Q9ZD20 | Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex | 1.82e-12 | 2.08e-48 | 2.90e-44 | 0.6753 |
| 1. PBF | Q89AJ6 | Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex | 0.00e+00 | 9.93e-42 | 2.61e-40 | 0.6843 |
| 1. PBF | O66119 | Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex | 0.00e+00 | 6.20e-61 | 8.01e-50 | 0.6075 |
| 1. PBF | P65635 | Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex | 1.44e-15 | 3.56e-70 | 9.33e-78 | 0.5264 |
| 1. PBF | Q8K9N2 | Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex | 3.39e-14 | 1.05e-32 | 8.95e-34 | 0.6597 |
| 1. PBF | P57302 | Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex | 0.00e+00 | 3.19e-38 | 1.40e-51 | 0.5597 |
| 1. PBF | Q9R9N3 | Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex | 1.11e-16 | 4.75e-54 | 1.74e-34 | 0.5898 |
| 1. PBF | Q49110 | Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex | 0.00e+00 | 4.40e-111 | 0.0 | 0.6909 |
| 1. PBF | Q1RHI5 | Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex | 3.66e-15 | 2.91e-47 | 3.26e-50 | 0.6435 |
| 1. PBF | P11181 | Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial | 0.00e+00 | 3.43e-21 | 2.58e-60 | 0.5368 |
| 1. PBF | Q6GAB9 | Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex | 1.11e-16 | 5.47e-70 | 7.14e-78 | 0.5258 |
| 1. PBF | P52993 | Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex | 0.00e+00 | 4.37e-42 | 2.09e-40 | 0.6368 |
| 1. PBF | Q9I1M0 | Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex | 2.71e-14 | 1.16e-53 | 1.01e-59 | 0.6423 |
| 1. PBF | Q6GHZ0 | Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex | 1.60e-14 | 1.46e-69 | 9.43e-78 | 0.527 |
| 1. PBF | O31550 | Dihydrolipoyllysine-residue acetyltransferase component of acetoin cleaving system | 0.00e+00 | 2.47e-56 | 1.68e-59 | 0.6041 |
| 1. PBF | P16263 | Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex | 1.60e-11 | 2.54e-54 | 8.70e-58 | 0.6861 |
| 1. PBF | Q59098 | Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex | 2.25e-11 | 4.91e-25 | 9.10e-50 | 0.5703 |
| 1. PBF | P9WIS6 | Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex | 1.23e-11 | 2.70e-31 | 6.04e-29 | 0.5616 |
| 1. PBF | Q2YY06 | Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex | 1.11e-16 | 1.33e-55 | 3.16e-47 | 0.6775 |
| 1. PBF | Q5HPC7 | Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex | 3.41e-11 | 1.68e-50 | 1.42e-50 | 0.6764 |
| 1. PBF | Q6ABX9 | Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex | 1.89e-15 | 8.55e-55 | 1.88e-47 | 0.6472 |
| 1. PBF | Q8NX76 | Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex | 1.11e-16 | 5.47e-70 | 7.14e-78 | 0.529 |
| 1. PBF | Q89AQ9 | Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex | 0.00e+00 | 1.00e-44 | 1.96e-43 | 0.574 |
| 1. PBF | Q8NNJ2 | Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex | 1.37e-10 | 2.06e-08 | 1.78e-37 | 0.6314 |
| 3. BF | A0PVU7 | Multifunctional 2-oxoglutarate metabolism enzyme | 3.27e-04 | NA | 8.37e-13 | 0.5456 |
| 3. BF | Q1B4V6 | Multifunctional 2-oxoglutarate metabolism enzyme | 6.52e-04 | NA | 4.26e-14 | 0.5287 |
| 3. BF | P86197 | Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial (Fragments) | 7.70e-08 | NA | 1.41e-19 | 0.6928 |
| 3. BF | A3Q3N5 | Multifunctional 2-oxoglutarate metabolism enzyme | 4.90e-04 | NA | 4.45e-14 | 0.5339 |
| 3. BF | A1KI36 | Multifunctional 2-oxoglutarate metabolism enzyme | 1.06e-04 | NA | 3.39e-12 | 0.5843 |
| 3. BF | Q8NRC3 | 2-oxoglutarate dehydrogenase E1/E2 component | 1.47e-04 | NA | 5.18e-13 | 0.5724 |
| 3. BF | P9WIS4 | Multifunctional 2-oxoglutarate metabolism enzyme | 6.21e-05 | NA | 3.45e-12 | 0.5914 |
| 3. BF | A0R2B1 | Multifunctional 2-oxoglutarate metabolism enzyme | 2.08e-04 | NA | 3.47e-12 | 0.6167 |
| 3. BF | A1TDK2 | Multifunctional 2-oxoglutarate metabolism enzyme | 2.28e-04 | NA | 5.07e-13 | 0.5486 |
| 3. BF | A1UK81 | Multifunctional 2-oxoglutarate metabolism enzyme | 4.61e-04 | NA | 4.26e-14 | 0.5311 |
| 4. PB | Q19749 | Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial | 4.55e-15 | 5.94e-13 | 1.02e-34 | NA |
| 4. PB | Q9M7Z1 | Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial | 0.00e+00 | 3.88e-17 | 1.90e-47 | NA |
| 4. PB | O94681 | Probable dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial | 5.22e-15 | 4.31e-20 | 3.10e-52 | NA |
| 4. PB | Q01205 | Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial | 4.29e-14 | 7.59e-14 | 6.91e-35 | NA |
| 4. PB | P19262 | Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial | 1.32e-13 | 6.93e-14 | 4.44e-56 | NA |
| 4. PB | Q8BMF4 | Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial | 4.55e-15 | 2.79e-03 | 3.04e-35 | NA |
| 4. PB | Q9C8P0 | Dihydrolipoyllysine-residue acetyltransferase component 5 of pyruvate dehydrogenase complex, chloroplastic | 5.51e-12 | 1.07e-25 | 5.23e-15 | NA |
| 4. PB | Q9FLQ4 | Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex 1, mitochondrial | 1.11e-16 | 6.93e-10 | 5.71e-37 | NA |
| 4. PB | P36957 | Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial | 1.58e-13 | 7.09e-13 | 4.92e-34 | NA |
| 4. PB | P08461 | Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial | 3.25e-13 | 3.92e-03 | 4.66e-34 | NA |
| 4. PB | O59816 | Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial | 4.44e-16 | 1.54e-25 | 3.82e-39 | NA |
| 4. PB | Q9D2G2 | Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial | 2.33e-15 | 4.98e-13 | 4.27e-35 | NA |
| 4. PB | Q8BKZ9 | Pyruvate dehydrogenase protein X component, mitochondrial | 3.12e-12 | 2.52e-16 | 1.63e-36 | NA |
| 4. PB | Q2FYM2 | Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex | 3.33e-16 | 1.12e-54 | 1.27e-46 | NA |
| 4. PB | P11182 | Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial | 2.19e-14 | 9.84e-18 | 8.21e-57 | NA |
| 4. PB | P10515 | Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial | 8.83e-10 | 2.79e-03 | 1.47e-32 | NA |
| 4. PB | P0AFG6 | Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex | 0.00e+00 | 1.05e-44 | 7.24e-46 | NA |
| 4. PB | Q8RWN9 | Dihydrolipoyllysine-residue acetyltransferase component 2 of pyruvate dehydrogenase complex, mitochondrial | 2.33e-15 | 5.83e-06 | 1.04e-42 | NA |
| 4. PB | Q9SQI8 | Dihydrolipoyllysine-residue acetyltransferase component 4 of pyruvate dehydrogenase complex, chloroplastic | 6.03e-13 | 3.10e-18 | 3.35e-20 | NA |
| 4. PB | P53395 | Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial | 1.11e-16 | 2.25e-18 | 3.41e-57 | NA |
| 4. PB | P9WIS7 | Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex | 2.87e-13 | 2.70e-31 | 6.04e-29 | NA |
| 4. PB | P06959 | Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex | 1.41e-14 | 4.33e-14 | 4.75e-61 | NA |
| 4. PB | Q869Y7 | Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial | 1.11e-16 | 4.42e-13 | 4.12e-37 | NA |
| 4. PB | Q0WQF7 | Dihydrolipoyllysine-residue acetyltransferase component 1 of pyruvate dehydrogenase complex, mitochondrial | 4.02e-12 | 4.08e-03 | 1.57e-27 | NA |
| 4. PB | Q86AD5 | Pyruvate dehydrogenase complex subunit homolog DDB_G0271564, mitochondrial | 1.52e-11 | 8.62e-05 | 1.89e-19 | NA |
| 4. PB | Q23571 | Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial | 5.55e-16 | 4.54e-36 | 4.51e-49 | NA |
| 4. PB | P12695 | Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial | 0.00e+00 | 2.47e-26 | 1.48e-25 | NA |
| 4. PB | O06159 | Dihydrolipoyllysine-residue acyltransferase component of branched-chain alpha-ketoacid dehydrogenase complex | 0.00e+00 | 2.89e-36 | 6.40e-47 | NA |
| 4. PB | Q5M729 | Dihydrolipoyllysine-residue acetyltransferase component 3 of pyruvate dehydrogenase complex, mitochondrial | 4.44e-16 | 1.10e-05 | 5.91e-50 | NA |
| 4. PB | O00330 | Pyruvate dehydrogenase protein X component, mitochondrial | 5.75e-12 | 1.00e-16 | 3.25e-35 | NA |
| 4. PB | Q8H107 | Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex 2, mitochondrial | 4.44e-16 | 2.53e-09 | 1.00e-38 | NA |
| 4. PB | P36413 | Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial | 2.56e-10 | 1.24e-04 | 1.07e-41 | NA |
| 5. P | O94709 | Probable pyruvate dehydrogenase protein X component, mitochondrial | 4.24e-05 | 2.52e-02 | NA | NA |
| 6. F | P27747 | Dihydrolipoyllysine-residue acetyltransferase component of acetoin cleaving system | 3.75e-02 | NA | NA | 0.9101 |
| 6. F | O66113 | Pyruvate dehydrogenase E1 component subunit beta | 1.49e-02 | NA | NA | 0.5415 |
| 6. F | Q9R9N4 | Pyruvate dehydrogenase E1 component subunit beta | 1.10e-02 | NA | NA | 0.647 |
| 6. F | Q59695 | Dihydrolipoyllysine-residue acetyltransferase component of acetoin cleaving system | 4.33e-02 | NA | NA | 0.9277 |
| 7. B | Q8XGX8 | Oxaloacetate decarboxylase alpha chain | 7.20e-01 | NA | 0.033 | NA |
| 7. B | A0A0H3JRU9 | Pyruvate carboxylase | 8.38e-01 | NA | 0.003 | NA |
| 7. B | Q612F5 | Propionyl-CoA carboxylase alpha chain, mitochondrial | 6.18e-01 | NA | 0.002 | NA |
| 7. B | Q9KWU4 | Pyruvate carboxylase | 8.82e-01 | NA | 0.002 | NA |
| 7. B | Q5XAE6 | Biotin carboxyl carrier protein of acetyl-CoA carboxylase | 3.22e-04 | NA | 0.023 | NA |
| 7. B | P86219 | Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial (Fragments) | 3.03e-04 | NA | 8.00e-05 | NA |
| 7. B | P0DTA4 | Propionyl-CoA carboxylase alpha chain, mitochondrial | 6.07e-01 | NA | 0.002 | NA |
| 7. B | Q58628 | Pyruvate carboxylase subunit B | 7.22e-01 | NA | 0.015 | NA |
| 7. B | Q03030 | Oxaloacetate decarboxylase alpha chain | 7.05e-01 | NA | 0.024 | NA |
| 7. B | Q5LUF3 | Propionyl-CoA carboxylase alpha chain | 5.82e-01 | NA | 0.005 | NA |
| 7. B | A5U1U6 | Multifunctional 2-oxoglutarate metabolism enzyme | 4.36e-05 | NA | 3.45e-12 | NA |
| 7. B | P14882 | Propionyl-CoA carboxylase alpha chain, mitochondrial | 4.76e-01 | NA | 0.001 | NA |
| 7. B | Q1XDK5 | Biotin carboxyl carrier protein of acetyl-CoA carboxylase | 1.65e-04 | NA | 0.022 | NA |
| 7. B | D3DJ41 | 2-oxoglutarate carboxylase large subunit | 5.99e-01 | NA | 2.24e-04 | NA |
| 7. B | P13187 | Oxaloacetate decarboxylase alpha chain | 7.23e-01 | NA | 0.004 | NA |
| 7. B | P9WIS5 | Multifunctional 2-oxoglutarate metabolism enzyme | 3.39e-04 | NA | 3.45e-12 | NA |
| 7. B | Q19842 | Propionyl-CoA carboxylase alpha chain, mitochondrial | 5.95e-01 | NA | 0.002 | NA |
| 7. B | Q73WX4 | Multifunctional 2-oxoglutarate metabolism enzyme | 1.90e-03 | NA | 1.36e-12 | NA |
| 7. B | Q06881 | Biotin carboxyl carrier protein of acetyl-CoA carboxylase | 1.76e-04 | NA | 0.041 | NA |
| 7. B | P02904 | Methylmalonyl-CoA carboxyltransferase 1.3S subunit | 8.86e-05 | NA | 5.32e-04 | NA |
| 7. B | P29337 | Biotin carboxyl carrier protein | 3.69e-05 | NA | 1.02e-06 | NA |
| 7. B | P31051 | Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex (Fragment) | 8.64e-04 | NA | 1.37e-05 | NA |
| 7. B | Q9XCD6 | Biotinylated protein TB7.3 homolog | 5.54e-06 | NA | 0.033 | NA |
| 7. B | P05165 | Propionyl-CoA carboxylase alpha chain, mitochondrial | 4.51e-01 | NA | 0.044 | NA |
| 7. B | Q9CC97 | Multifunctional 2-oxoglutarate metabolism enzyme | 7.79e-04 | NA | 3.09e-13 | NA |
| 7. B | Q7U0A6 | Multifunctional 2-oxoglutarate metabolism enzyme | 1.80e-04 | NA | 3.39e-12 | NA |
| 7. B | Q91ZA3 | Propionyl-CoA carboxylase alpha chain, mitochondrial | 4.98e-01 | NA | 0.001 | NA |