Summary
The literature section presents previous knowledge about this protein. There have been five different efforts to annotate minimal organism genome. The annotations from those efforts are given in the Literature section for completeness.
AVX54724.1
JCVISYN3A_0329
Uncharacterized pseudouridine synthase.
M. mycoides homolog: Q6MTL6.
TIGRfam Classification: 4=Probable.
Category: Quasiessential.
Statistics
Total GO Annotation: 25
Unique PROST Go: 6
Unique BLAST Go: 4
Unique Foldseek Go: 3
Total Homologs: 278
Unique PROST Homologs: 51
Unique BLAST Homologs: 1
Unique Foldseek Homologs: 106
Structures and Sequence Alignment
The best structural homolog that predicted by 1. PBF was
Q87NB7
(Ribosomal large subunit pseudouridine synthase B) with a FATCAT P-Value: 0 and RMSD of 2.24 angstrom. The sequence alignment identity is 29.1%.
Structural alignment shown in left. Query protein AVX54724.1 colored as red in alignment, homolog Q87NB7 colored as blue.
Query protein AVX54724.1 is also shown in right top, homolog Q87NB7 showed in right bottom. They are colored based on secondary structures.
AVX54724.1 MSLERLQKVISSRGYCSRRAAEKLILENRVKVNDQIINTLGVKI-DPKAEIKIDNKLVLSDSNNQKYY--YL-FYKPRLVLTTMYDPKKRKTVNDYF-KD 95 Q87NB7 MS-EKLQKVLARAGHGSRREIESLIKSGRVSVNG-VVAKLGERLEDESSVVRIDGHIV-SAKVQEEVICRVLAYYKPEGELCTRHDPEGRRTVFDRLPKI 97 AVX54724.1 LNHRVYPVGRLDYDVSGLLLMTNDGVLSNFIMHPKYEFLKTYQGLCQ--GQVNKQQINQLIKGVYIDNDYLTKAYSAKLVKY---DKLKNTSIVELTINE 190 Q87NB7 RGSRWISVGRLDANTSGLLLFTTDGELANRLMHPSRQVEREY--LVRVFGEVTEQKVRNLVKGVELE-DGLARF--EDVV-YAGGEGMNHT--FYVVINE 189 AVX54724.1 GKKHHVKKMFESIQAQLLKLKRTKI-E-FLEIADLK-P-GQYRELKTHEVKRLYGIYH---------SLKQDNNK------------------------- 252 Q87NB7 GRNREVRRLWESQECTVSRLKRVRYGDIFL---DKKLPRGGWMELDLKEVNYLRELVELRPEKETMLDLSKDNTSRKRERARSQKIRRAVKRHEERVSTS 286 AVX54724.1 -------------------------- 252 Q87NB7 KGRSNNPARRKPKKNAGEQGARNKHR 312
Go Annotations
1. PBF indicates the go terms that are found by both PROST and BLAST and Foldseek.
2. PF indicates the go terms that are found by only PROST and Foldseek.
3. BF indicates the go terms that are found by only BLAST and Foldseek.
4. PB indicates the go terms that are found by both PROST and BLAST.
5. P indicates the go terms that are found by only PROST.
6. F indicates the go terms that are found by only Foldseek.
7. B indicates the go terms that are found by only BLAST.
| Source | GO | Description |
|---|---|---|
| 1. PBF | GO:0008033 | tRNA processing |
| 1. PBF | GO:0000455 | enzyme-directed rRNA pseudouridine synthesis |
| 1. PBF | GO:0003723 | RNA binding |
| 1. PBF | GO:0001522 | pseudouridine synthesis |
| 1. PBF | GO:0009982 | pseudouridine synthase activity |
| 1. PBF | GO:0000154 | rRNA modification |
| 1. PBF | GO:0009451 | RNA modification |
| 1. PBF | GO:0006364 | rRNA processing |
| 1. PBF | GO:0120159 | rRNA pseudouridine synthase activity |
| 2. PF | GO:0031118 | rRNA pseudouridine synthesis |
| 2. PF | GO:0106029 | tRNA pseudouridine synthase activity |
| 2. PF | GO:0031119 | tRNA pseudouridine synthesis |
| 5. P | GO:0070131 | positive regulation of mitochondrial translation |
| 5. P | GO:0035770 | ribonucleoprotein granule |
| 5. P | GO:1990400 | mitochondrial ribosomal large subunit rRNA binding |
| 5. P | GO:0005737 | cytoplasm |
| 5. P | GO:0070902 | mitochondrial tRNA pseudouridine synthesis |
| 5. P | GO:0005759 | mitochondrial matrix |
| 6. F | GO:0000495 | box H/ACA RNA 3'-end processing |
| 6. F | GO:0031120 | snRNA pseudouridine synthesis |
| 6. F | GO:1990481 | mRNA pseudouridine synthesis |
| 7. B | GO:0000489 | maturation of SSU-rRNA from tetracistronic rRNA transcript (SSU-rRNA, LSU-rRNA, 4.5S-rRNA, 5S-rRNA) |
| 7. B | GO:0009501 | amyloplast |
| 7. B | GO:0000488 | maturation of LSU-rRNA from tetracistronic rRNA transcript (SSU-rRNA, LSU-rRNA, 4.5S-rRNA, 5S-rRNA) |
| 7. B | GO:0032544 | plastid translation |
Uniprot GO Annotations
| GO | Description |
|---|---|
| GO:0004730 | pseudouridylate synthase activity |
| GO:0003723 | RNA binding |
| GO:0016829 | lyase activity |
| GO:0001522 | pseudouridine synthesis |
| GO:0009982 | pseudouridine synthase activity |
Homologs
1. PBF indicates the homologs that are found by both PROST and BLAST and Foldseek.
2. PF indicates the homologs that are found by only PROST and Foldseek.
3. BF indicates the homologs that are found by only BLAST and Foldseek.
4. PB indicates the homologs that are found by both PROST and BLAST.
5. P indicates the homologs that are found by only PROST.
6. F indicates the homologs that are found by only Foldseek.
7. B indicates the homologs that are found by only BLAST.
| Source | Homolog | Description | Fatcat Pvalue | PROST Evalue | BLAST Evalue | Foldseek TMScore |
|---|---|---|---|---|---|---|
| 1. PBF | Q8FIB6 | Ribosomal large subunit pseudouridine synthase E | 5.04e-14 | 6.33e-12 | 1.07e-10 | 0.8327 |
| 1. PBF | O66829 | Uncharacterized RNA pseudouridine synthase aq_554 | 0.00e+00 | 3.94e-58 | 1.07e-23 | 0.7298 |
| 1. PBF | Q9CPN4 | Ribosomal small subunit pseudouridine synthase A | 0.00e+00 | 3.70e-42 | 2.03e-19 | 0.6971 |
| 1. PBF | Q87QY8 | Ribosomal large subunit pseudouridine synthase E | 3.13e-13 | 4.43e-12 | 1.31e-18 | 0.7748 |
| 1. PBF | Q8ZEG0 | Ribosomal large subunit pseudouridine synthase B | 0.00e+00 | 4.53e-04 | 7.33e-27 | 0.8969 |
| 1. PBF | P45104 | Ribosomal large subunit pseudouridine synthase B | 0.00e+00 | 3.60e-09 | 4.94e-27 | 0.908 |
| 1. PBF | Q9CKK7 | Ribosomal large subunit pseudouridine synthase E | 6.11e-15 | 4.65e-16 | 9.49e-20 | 0.7784 |
| 1. PBF | Q8PQN3 | Ribosomal large subunit pseudouridine synthase E | 1.78e-15 | 7.63e-07 | 1.35e-16 | 0.8256 |
| 1. PBF | Q83LF6 | Ribosomal large subunit pseudouridine synthase E | 1.78e-14 | 1.15e-12 | 2.48e-11 | 0.8325 |
| 1. PBF | Q8X724 | Ribosomal large subunit pseudouridine synthase E | 1.14e-13 | 2.71e-12 | 3.66e-11 | 0.8378 |
| 1. PBF | Q8ZGM2 | Ribosomal small subunit pseudouridine synthase A | 0.00e+00 | 4.05e-42 | 1.02e-25 | 0.6601 |
| 1. PBF | Q89AL1 | Ribosomal large subunit pseudouridine synthase B | 0.00e+00 | 7.59e-48 | 9.42e-22 | 0.8925 |
| 1. PBF | Q8ZKL1 | Dual-specificity RNA pseudouridine synthase RluF | 0.00e+00 | 6.91e-10 | 5.48e-17 | 0.8859 |
| 1. PBF | P65843 | Uncharacterized RNA pseudouridine synthase Mb1738 | 0.00e+00 | 7.59e-44 | 8.40e-43 | 0.7057 |
| 1. PBF | Q87QD4 | Ribosomal small subunit pseudouridine synthase A | 0.00e+00 | 4.08e-35 | 1.07e-16 | 0.6642 |
| 1. PBF | Q8FHV4 | Ribosomal large subunit pseudouridine synthase B | 0.00e+00 | 2.85e-18 | 2.81e-28 | 0.8753 |
| 1. PBF | P45124 | Ribosomal small subunit pseudouridine synthase A | 0.00e+00 | 1.05e-39 | 1.17e-21 | 0.7202 |
| 1. PBF | Q9CMY9 | Ribosomal large subunit pseudouridine synthase B | 0.00e+00 | 9.56e-13 | 1.77e-30 | 0.9051 |
| 1. PBF | P0AA45 | Ribosomal small subunit pseudouridine synthase A | 0.00e+00 | 4.25e-34 | 1.80e-28 | 0.6795 |
| 1. PBF | Q8X4Q8 | Ribosomal large subunit pseudouridine synthase B | 0.00e+00 | 3.84e-19 | 5.01e-28 | 0.875 |
| 1. PBF | O67444 | Uncharacterized RNA pseudouridine synthase aq_1464 | 0.00e+00 | 1.17e-56 | 2.22e-54 | 0.9341 |
| 1. PBF | P9WHQ0 | Uncharacterized RNA pseudouridine synthase MT1751.1 | 0.00e+00 | 7.59e-44 | 8.40e-43 | 0.9302 |
| 1. PBF | Q68WJ1 | Uncharacterized RNA pseudouridine synthase RT0532 | 0.00e+00 | 6.32e-45 | 1.84e-32 | 0.8894 |
| 1. PBF | P35159 | Ribosomal large subunit pseudouridine synthase B | 0.00e+00 | 1.91e-62 | 3.08e-68 | 0.9439 |
| 1. PBF | O05668 | Uncharacterized RNA pseudouridine synthase ML1370 | 0.00e+00 | 1.31e-38 | 3.30e-41 | 0.93 |
| 1. PBF | Q8PDR2 | Ribosomal large subunit pseudouridine synthase E | 4.44e-16 | 2.74e-07 | 2.82e-19 | 0.7921 |
| 1. PBF | P44827 | Ribosomal large subunit pseudouridine synthase E | 4.44e-15 | 2.41e-20 | 1.91e-21 | 0.7817 |
| 1. PBF | Q87NB7 | Ribosomal large subunit pseudouridine synthase B | 0.00e+00 | 1.89e-05 | 3.37e-30 | 0.9093 |
| 1. PBF | Q92HG4 | Uncharacterized RNA pseudouridine synthase RC0807 | 0.00e+00 | 2.23e-38 | 8.66e-27 | 0.9194 |
| 1. PBF | Q9F855 | Ribosomal large subunit pseudouridine synthase E | 4.25e-13 | 2.00e-09 | 6.09e-18 | 0.8164 |
| 1. PBF | P59815 | Ribosomal large subunit pseudouridine synthase B | 0.00e+00 | 4.03e-19 | 4.91e-28 | 0.8745 |
| 1. PBF | Q8Z7D5 | Ribosomal large subunit pseudouridine synthase B | 0.00e+00 | 1.90e-18 | 9.14e-30 | 0.8756 |
| 1. PBF | Q9ZJG0 | Uncharacterized RNA pseudouridine synthase jhp_1352 | 0.00e+00 | 3.08e-43 | 9.12e-21 | 0.7776 |
| 1. PBF | Q8FB47 | Dual-specificity RNA pseudouridine synthase RluF | 0.00e+00 | 1.59e-09 | 1.34e-18 | 0.8905 |
| 1. PBF | Q9KRK5 | Ribosomal small subunit pseudouridine synthase A | 0.00e+00 | 1.92e-40 | 1.02e-16 | 0.6851 |
| 1. PBF | P0AA44 | Ribosomal small subunit pseudouridine synthase A | 0.00e+00 | 4.25e-34 | 1.80e-28 | 0.6789 |
| 1. PBF | Q9I5J6 | Ribosomal small subunit pseudouridine synthase A | 0.00e+00 | 1.34e-41 | 3.70e-21 | 0.6662 |
| 1. PBF | Q1RJR2 | Uncharacterized RNA pseudouridine synthase RBE_0321 | 0.00e+00 | 8.69e-38 | 8.73e-31 | 0.907 |
| 1. PBF | P0AA46 | Ribosomal small subunit pseudouridine synthase A | 0.00e+00 | 4.25e-34 | 1.80e-28 | 0.6794 |
| 1. PBF | P57369 | Ribosomal large subunit pseudouridine synthase B | 0.00e+00 | 6.29e-41 | 1.03e-21 | 0.9061 |
| 1. PBF | Q9HX48 | Ribosomal large subunit pseudouridine synthase E | 6.00e-15 | 4.47e-09 | 2.89e-23 | 0.8445 |
| 1. PBF | Q55578 | Uncharacterized RNA pseudouridine synthase slr0361 | 0.00e+00 | 1.45e-50 | 3.06e-38 | 0.8928 |
| 1. PBF | O32068 | Uncharacterized RNA pseudouridine synthase YtzG | 2.22e-16 | 7.94e-44 | 2.57e-28 | 0.687 |
| 1. PBF | P55986 | Uncharacterized RNA pseudouridine synthase HP_1459 | 0.00e+00 | 2.46e-43 | 5.17e-21 | 0.7448 |
| 1. PBF | Q9ZD06 | Uncharacterized RNA pseudouridine synthase RP544 | 0.00e+00 | 4.70e-40 | 1.58e-30 | 0.8914 |
| 1. PBF | Q8ZP51 | Ribosomal large subunit pseudouridine synthase B | 0.00e+00 | 4.90e-18 | 7.25e-30 | 0.8756 |
| 1. PBF | Q8Z7G6 | Ribosomal large subunit pseudouridine synthase E | 1.44e-13 | 8.27e-11 | 2.25e-12 | 0.8368 |
| 1. PBF | Q4UL59 | Uncharacterized RNA pseudouridine synthase RF_0863 | 0.00e+00 | 6.57e-41 | 4.61e-29 | 0.9167 |
| 1. PBF | Q9KSS7 | Ribosomal large subunit pseudouridine synthase B | 0.00e+00 | 9.17e-04 | 4.10e-28 | 0.9091 |
| 1. PBF | P42395 | Ribosomal large subunit pseudouridine synthase B | 0.00e+00 | 2.50e-39 | 1.46e-27 | 0.901 |
| 1. PBF | Q8D8X2 | Ribosomal small subunit pseudouridine synthase A | 0.00e+00 | 1.71e-41 | 2.49e-20 | 0.6757 |
| 1. PBF | Q8D8C0 | Ribosomal large subunit pseudouridine synthase B | 0.00e+00 | 3.68e-04 | 5.00e-30 | 0.9054 |
| 1. PBF | Q8DAS3 | Ribosomal large subunit pseudouridine synthase E | 1.42e-13 | 1.44e-13 | 2.47e-18 | 0.8012 |
| 1. PBF | Q8X4L9 | Dual-specificity RNA pseudouridine synthase RluF | 0.00e+00 | 2.17e-09 | 2.81e-18 | 0.875 |
| 1. PBF | Q8ZFQ3 | Ribosomal large subunit pseudouridine synthase E | 1.28e-13 | 2.04e-17 | 3.97e-16 | 0.8253 |
| 1. PBF | P65841 | Ribosomal small subunit pseudouridine synthase A | 0.00e+00 | 6.95e-35 | 1.13e-26 | 0.6759 |
| 1. PBF | P65840 | Ribosomal small subunit pseudouridine synthase A | 0.00e+00 | 6.95e-35 | 1.13e-26 | 0.6809 |
| 1. PBF | Q8ZPZ1 | Ribosomal large subunit pseudouridine synthase E | 9.87e-14 | 2.80e-10 | 1.92e-12 | 0.8326 |
| 1. PBF | Q8Z1V3 | Dual-specificity RNA pseudouridine synthase RluF | 0.00e+00 | 1.50e-10 | 3.56e-17 | 0.8811 |
| 1. PBF | O51155 | Uncharacterized RNA pseudouridine synthase BB_0129 | 0.00e+00 | 1.32e-48 | 4.82e-20 | 0.8897 |
| 1. PBF | Q83IR6 | Dual-specificity RNA pseudouridine synthase RluF | 0.00e+00 | 2.17e-09 | 3.77e-18 | 0.8782 |
| 2. PF | P57430 | Ribosomal large subunit pseudouridine synthase C | 7.13e-06 | 4.27e-07 | NA | 0.5545 |
| 2. PF | Q9L7A7 | Ribosomal large subunit pseudouridine synthase D | 1.55e-06 | 1.06e-05 | NA | 0.4268 |
| 2. PF | Q8K9J8 | Ribosomal large subunit pseudouridine synthase C | 5.36e-06 | 5.29e-06 | NA | 0.5205 |
| 2. PF | P44445 | Ribosomal large subunit pseudouridine synthase D | 1.50e-06 | 3.62e-07 | NA | 0.4317 |
| 2. PF | Q9ZMA1 | Uncharacterized RNA pseudouridine synthase jhp_0321 | 5.47e-07 | 7.95e-06 | NA | 0.5032 |
| 2. PF | Q9KQH0 | Ribosomal large subunit pseudouridine synthase C | 3.14e-07 | 6.26e-06 | NA | 0.5764 |
| 2. PF | Q8D8G1 | Ribosomal large subunit pseudouridine synthase C | 2.73e-07 | 2.08e-06 | NA | 0.6106 |
| 2. PF | Q9CKA6 | Ribosomal large subunit pseudouridine synthase D | 6.43e-06 | 2.66e-06 | NA | 0.4483 |
| 2. PF | P47610 | Uncharacterized RNA pseudouridine synthase MG370 | 1.73e-06 | 7.34e-08 | NA | 0.4954 |
| 2. PF | Q8DEV0 | Ribosomal large subunit pseudouridine synthase D | 1.57e-06 | 1.91e-08 | NA | 0.4405 |
| 2. PF | P59831 | Dual-specificity RNA pseudouridine synthase RluA | 1.50e-06 | 1.79e-07 | NA | 0.6296 |
| 2. PF | Q8FL93 | Dual-specificity RNA pseudouridine synthase RluA | 6.53e-07 | 9.20e-06 | NA | 0.5528 |
| 2. PF | P74346 | Uncharacterized RNA pseudouridine synthase slr1629 | 2.38e-06 | 5.01e-03 | NA | 0.4793 |
| 2. PF | Q8XA10 | Dual-specificity RNA pseudouridine synthase RluA | 6.69e-07 | 4.52e-06 | NA | 0.5512 |
| 2. PF | P54604 | Uncharacterized RNA pseudouridine synthase YhcT | 1.09e-06 | 1.70e-06 | NA | 0.4747 |
| 2. PF | Q45480 | Uncharacterized RNA pseudouridine synthase YlyB | 3.98e-06 | 2.87e-06 | NA | 0.4454 |
| 2. PF | Q89AH2 | Ribosomal large subunit pseudouridine synthase C | 3.71e-05 | 1.28e-07 | NA | 0.5087 |
| 2. PF | O25114 | Uncharacterized RNA pseudouridine synthase HP_0347 | 5.89e-06 | 1.25e-04 | NA | 0.5061 |
| 2. PF | P65834 | Ribosomal large subunit pseudouridine synthase D | 1.67e-06 | 2.12e-07 | NA | 0.4411 |
| 2. PF | Q9ZL98 | Uncharacterized RNA pseudouridine synthase jhp_0682 | 2.46e-06 | 1.17e-07 | NA | 0.4821 |
| 2. PF | Q9HZM9 | Ribosomal large subunit pseudouridine synthase C | 4.33e-06 | 6.70e-08 | NA | 0.5266 |
| 2. PF | O67638 | Uncharacterized RNA pseudouridine synthase aq_1758 | 5.30e-07 | 3.44e-05 | NA | 0.4873 |
| 2. PF | Q87S65 | Ribosomal large subunit pseudouridine synthase D | 1.39e-06 | 8.04e-08 | NA | 0.4384 |
| 2. PF | Q8ZRV9 | Dual-specificity RNA pseudouridine synthase RluA | 9.13e-07 | 3.36e-06 | NA | 0.5419 |
| 2. PF | P45614 | Uncharacterized RNA pseudouridine synthase MCAP_0714 | 3.45e-06 | 5.71e-08 | NA | 0.4886 |
| 2. PF | Q8ZIK1 | Dual-specificity RNA pseudouridine synthase RluA | 5.90e-07 | 9.69e-04 | NA | 0.5592 |
| 2. PF | Q8K9E9 | Ribosomal large subunit pseudouridine synthase D | 5.65e-06 | 2.96e-07 | NA | 0.4476 |
| 2. PF | O25610 | Uncharacterized RNA pseudouridine synthase HP_0956 | 1.51e-07 | 4.47e-09 | NA | 0.4388 |
| 2. PF | Q8Z9J5 | Dual-specificity RNA pseudouridine synthase RluA | 9.15e-07 | 2.27e-06 | NA | 0.5421 |
| 2. PF | P9WHQ2 | Uncharacterized RNA pseudouridine synthase MT1592 | 2.12e-06 | 8.27e-11 | NA | 0.4396 |
| 2. PF | Q9ZKP5 | Uncharacterized RNA pseudouridine synthase jhp_0890 | 1.34e-07 | 6.17e-11 | NA | 0.4399 |
| 2. PF | O31613 | Uncharacterized RNA pseudouridine synthase YjbO | 1.69e-05 | 1.14e-04 | NA | 0.4682 |
| 2. PF | P59835 | Ribosomal large subunit pseudouridine synthase C | 5.25e-06 | 2.62e-05 | NA | 0.555 |
| 2. PF | P59838 | Ribosomal large subunit pseudouridine synthase D | 5.16e-06 | 6.39e-06 | NA | 0.4598 |
| 2. PF | O50310 | Uncharacterized RNA pseudouridine synthase Cpar_0723 | 1.73e-06 | 1.68e-08 | NA | 0.4473 |
| 2. PF | P75230 | Uncharacterized RNA pseudouridine synthase MG370 homolog | 1.82e-05 | 2.83e-09 | NA | 0.5152 |
| 2. PF | P75485 | Uncharacterized RNA pseudouridine synthase MG209 homolog | 1.78e-06 | 3.87e-09 | NA | 0.467 |
| 2. PF | P44782 | Dual-specificity RNA pseudouridine synthase RluA | 7.52e-07 | 1.02e-07 | NA | 0.5525 |
| 2. PF | P72970 | Uncharacterized RNA pseudouridine synthase slr1592 | 2.56e-06 | 1.01e-06 | NA | 0.4306 |
| 2. PF | Q9CK02 | Dual-specificity RNA pseudouridine synthase RluA | 7.89e-07 | 1.76e-08 | NA | 0.5517 |
| 2. PF | P0AA38 | Dual-specificity RNA pseudouridine synthase RluA | 6.06e-07 | 8.55e-06 | NA | 0.5536 |
| 2. PF | Q8ZBV7 | Ribosomal large subunit pseudouridine synthase D | 1.36e-06 | 3.54e-07 | NA | 0.4445 |
| 2. PF | Q47417 | tRNA pseudouridine synthase C | 4.49e-04 | 1.64e-02 | NA | 0.4964 |
| 2. PF | Q1RJX7 | Ribosomal large subunit pseudouridine synthase C | 1.55e-06 | 6.66e-11 | NA | 0.5104 |
| 2. PF | P59840 | tRNA pseudouridine synthase C | 3.26e-06 | 4.08e-02 | NA | 0.4561 |
| 2. PF | P47451 | Uncharacterized RNA pseudouridine synthase MG209 | 2.33e-06 | 5.46e-08 | NA | 0.4931 |
| 2. PF | O25441 | Uncharacterized RNA pseudouridine synthase HP_0745 | 4.39e-06 | 1.32e-07 | NA | 0.5393 |
| 2. PF | Q87N15 | Ribosomal large subunit pseudouridine synthase C | 2.56e-07 | 8.60e-07 | NA | 0.5832 |
| 3. BF | Q8P8M6 | Ribosomal large subunit pseudouridine synthase B | 0.00e+00 | NA | 2.74e-20 | 0.8855 |
| 3. BF | Q87BI2 | Ribosomal large subunit pseudouridine synthase B | 0.00e+00 | NA | 1.18e-19 | 0.884 |
| 3. BF | Q9HZ55 | Ribosomal large subunit pseudouridine synthase B | 0.00e+00 | NA | 2.50e-27 | 0.9157 |
| 3. BF | Q8PK58 | Ribosomal large subunit pseudouridine synthase B | 0.00e+00 | NA | 2.10e-19 | 0.8856 |
| 3. BF | Q9PAP2 | Ribosomal large subunit pseudouridine synthase B | 0.00e+00 | NA | 1.48e-19 | 0.8839 |
| 4. PB | P32684 | Dual-specificity RNA pseudouridine synthase RluF | 0.00e+00 | 3.69e-09 | 1.29e-18 | NA |
| 4. PB | P0AA43 | Ribosomal small subunit pseudouridine synthase A | 0.00e+00 | 4.25e-34 | 1.80e-28 | NA |
| 4. PB | P37765 | Ribosomal large subunit pseudouridine synthase B | 0.00e+00 | 2.72e-18 | 5.38e-28 | NA |
| 4. PB | P9WHQ1 | Uncharacterized RNA pseudouridine synthase Rv1711 | 0.00e+00 | 7.59e-44 | 8.40e-43 | NA |
| 4. PB | P72581 | Uncharacterized RNA pseudouridine synthase slr0612 | NA | 5.42e-15 | 5.14e-17 | NA |
| 4. PB | P75966 | Ribosomal large subunit pseudouridine synthase E | 6.18e-14 | 3.18e-12 | 2.16e-11 | NA |
| 5. P | Q9CWX4 | Mitochondrial RNA pseudouridine synthase Rpusd4 | 2.62e-04 | 4.47e-06 | NA | NA |
| 5. P | Q9PET9 | Ribosomal large subunit pseudouridine synthase D | 3.48e-06 | 3.07e-08 | NA | NA |
| 5. P | P9WHQ3 | Uncharacterized RNA pseudouridine synthase Rv1540 | 2.29e-06 | 8.27e-11 | NA | NA |
| 5. P | P50513 | Ribosomal large subunit pseudouridine synthase D | 5.03e-06 | 3.27e-09 | NA | NA |
| 5. P | P33640 | Ribosomal large subunit pseudouridine synthase D | 2.02e-06 | 7.02e-06 | NA | NA |
| 5. P | Q89AD9 | Ribosomal large subunit pseudouridine synthase D | 3.26e-06 | 7.34e-08 | NA | NA |
| 5. P | P0A5T3 | Uncharacterized RNA pseudouridine synthase Mb1567 | 2.33e-06 | 8.27e-11 | NA | NA |
| 5. P | P0AA37 | Dual-specificity RNA pseudouridine synthase RluA | 5.82e-07 | 8.55e-06 | NA | NA |
| 5. P | P0AA39 | Ribosomal large subunit pseudouridine synthase C | 4.47e-06 | 1.77e-06 | NA | NA |
| 5. P | P53294 | tRNA pseudouridine(31) synthase | 1.05e-04 | 5.58e-04 | NA | NA |
| 5. P | P65836 | Ribosomal large subunit pseudouridine synthase D | 2.04e-06 | 2.53e-07 | NA | NA |
| 5. P | Q8X9F0 | Ribosomal large subunit pseudouridine synthase D | 1.68e-06 | 1.88e-07 | NA | NA |
| 5. P | Q2TBK7 | Mitochondrial mRNA pseudouridine synthase RPUSD3 | 1.94e-03 | 6.55e-04 | NA | NA |
| 5. P | Q96CM3 | Mitochondrial RNA pseudouridine synthase RPUSD4 | 2.94e-04 | 1.20e-03 | NA | NA |
| 5. P | Q8FIP7 | Ribosomal large subunit pseudouridine synthase C | 4.31e-06 | 1.12e-06 | NA | NA |
| 5. P | Q4QQT0 | Mitochondrial RNA pseudouridine synthase Rpusd4 | 2.95e-04 | 2.09e-05 | NA | NA |
| 5. P | Q8ZQ16 | Ribosomal large subunit pseudouridine synthase C | 4.28e-06 | 1.23e-06 | NA | NA |
| 5. P | P65837 | Ribosomal large subunit pseudouridine synthase D | 1.98e-06 | 2.53e-07 | NA | NA |
| 5. P | P0AA40 | Ribosomal large subunit pseudouridine synthase C | 4.26e-06 | 1.77e-06 | NA | NA |
| 5. P | Q8P682 | Ribosomal large subunit pseudouridine synthase D | 2.96e-06 | 3.16e-09 | NA | NA |
| 5. P | Q8XYX8 | Ribosomal large subunit pseudouridine synthase D | 2.25e-05 | 5.77e-03 | NA | NA |
| 5. P | P33643 | Ribosomal large subunit pseudouridine synthase D | 8.41e-06 | 2.51e-07 | NA | NA |
| 5. P | P44433 | Ribosomal large subunit pseudouridine synthase C | 6.26e-07 | 8.43e-05 | NA | NA |
| 5. P | P57481 | Ribosomal large subunit pseudouridine synthase D | 5.49e-06 | 1.52e-10 | NA | NA |
| 5. P | Q9JVB6 | Ribosomal large subunit pseudouridine synthase D | 1.97e-05 | 5.03e-04 | NA | NA |
| 5. P | Q8PHN2 | Ribosomal large subunit pseudouridine synthase D | 3.05e-06 | 1.90e-07 | NA | NA |
| 5. P | Q82WZ5 | Ribosomal large subunit pseudouridine synthase D | 1.73e-05 | 1.53e-07 | NA | NA |
| 5. P | P65835 | Ribosomal large subunit pseudouridine synthase D | 1.70e-06 | 2.12e-07 | NA | NA |
| 5. P | Q6P087 | Mitochondrial mRNA pseudouridine synthase RPUSD3 | 3.72e-03 | 9.35e-03 | NA | NA |
| 5. P | Q8X8J3 | Ribosomal large subunit pseudouridine synthase C | 4.03e-07 | 1.79e-06 | NA | NA |
| 5. P | Q6DBR0 | Mitochondrial RNA pseudouridine synthase rpusd4 | 2.97e-04 | 2.39e-04 | NA | NA |
| 5. P | Q9ZDR7 | Ribosomal large subunit pseudouridine synthase C | 1.47e-05 | 1.44e-08 | NA | NA |
| 5. P | Q5Z8P2 | RNA pseudouridine synthase 2, chloroplastic | 3.33e-05 | 3.28e-02 | NA | NA |
| 5. P | Q0DST9 | RNA pseudouridine synthase 5 | 2.21e-06 | 6.26e-06 | NA | NA |
| 5. P | Q5M721 | RNA pseudouridine synthase 5 | 1.04e-06 | 1.64e-04 | NA | NA |
| 5. P | Q4UKQ3 | Ribosomal large subunit pseudouridine synthase C | 2.43e-05 | 9.17e-10 | NA | NA |
| 5. P | Q6CQC4 | 21S rRNA pseudouridine(2819) synthase | 1.71e-03 | 8.80e-03 | NA | NA |
| 5. P | Q8Z7J7 | Ribosomal large subunit pseudouridine synthase C | 4.49e-06 | 2.51e-07 | NA | NA |
| 5. P | Q7XA65 | RNA pseudouridine synthase 1 | 1.69e-05 | 2.15e-04 | NA | NA |
| 5. P | Q9K0B0 | Ribosomal large subunit pseudouridine synthase D | 1.79e-05 | 6.61e-04 | NA | NA |
| 5. P | Q0E0Y3 | RNA pseudouridine synthase 7 | 2.57e-05 | 2.00e-06 | NA | NA |
| 5. P | Q92IS6 | Ribosomal large subunit pseudouridine synthase C | 2.00e-06 | 7.35e-10 | NA | NA |
| 5. P | Q9KU20 | Ribosomal large subunit pseudouridine synthase D | 1.35e-06 | 2.14e-07 | NA | NA |
| 5. P | Q87AR7 | Ribosomal large subunit pseudouridine synthase D | 3.25e-06 | 1.13e-06 | NA | NA |
| 5. P | Q8ZFU1 | Ribosomal large subunit pseudouridine synthase C | 2.38e-06 | 6.27e-07 | NA | NA |
| 5. P | Q68XB2 | Ribosomal large subunit pseudouridine synthase C | 1.46e-05 | 5.82e-10 | NA | NA |
| 5. P | P70870 | Ribosomal large subunit pseudouridine synthase D | 9.91e-05 | 1.18e-07 | NA | NA |
| 5. P | Q9CM51 | Ribosomal large subunit pseudouridine synthase C | 1.48e-07 | 1.35e-05 | NA | NA |
| 5. P | Q9LU60 | RNA pseudouridine synthase 7 | 5.78e-05 | 8.20e-04 | NA | NA |
| 5. P | Q5E9Z1 | Mitochondrial RNA pseudouridine synthase RPUSD4 | 2.69e-04 | 3.20e-02 | NA | NA |
| 5. P | Q45826 | Uncharacterized RNA pseudouridine synthase Caur_0901 | 1.89e-06 | 4.02e-06 | NA | NA |
| 6. F | P65854 | tRNA pseudouridine synthase B | 7.87e-07 | NA | NA | 0.4429 |
| 6. F | A8MFB1 | tRNA pseudouridine synthase B | 5.23e-07 | NA | NA | 0.5162 |
| 6. F | Q5UXH1 | Probable tRNA pseudouridine synthase B | 7.26e-05 | NA | NA | 0.5305 |
| 6. F | Q30TG2 | tRNA pseudouridine synthase B | 6.88e-07 | NA | NA | 0.4379 |
| 6. F | A6LEL7 | tRNA pseudouridine synthase B | 1.09e-05 | NA | NA | 0.4527 |
| 6. F | Q4ULJ9 | tRNA pseudouridine synthase B | 3.64e-07 | NA | NA | 0.4729 |
| 6. F | Q8ZYB3 | Probable tRNA pseudouridine synthase B | 1.84e-05 | NA | NA | 0.5555 |
| 6. F | Q9RB36 | tRNA pseudouridine synthase B | 1.03e-07 | NA | NA | 0.4894 |
| 6. F | Q6L1A0 | Probable tRNA pseudouridine synthase B | 1.36e-05 | NA | NA | 0.557 |
| 6. F | Q601U7 | tRNA pseudouridine synthase B | 7.56e-07 | NA | NA | 0.5126 |
| 6. F | Q87MD4 | tRNA pseudouridine synthase C | 1.29e-05 | NA | NA | 0.5532 |
| 6. F | Q21H63 | tRNA pseudouridine synthase B | 5.27e-05 | NA | NA | 0.4946 |
| 6. F | Q1RIG2 | tRNA pseudouridine synthase B | 8.96e-08 | NA | NA | 0.4637 |
| 6. F | Q8X6T6 | tRNA pseudouridine synthase C | 4.19e-06 | NA | NA | 0.5377 |
| 6. F | Q8ZH72 | tRNA pseudouridine synthase C | 4.63e-06 | NA | NA | 0.5888 |
| 6. F | Q5XGG2 | Mitochondrial mRNA pseudouridine synthase Trub2 | 2.85e-03 | NA | NA | 0.3585 |
| 6. F | Q8XJS1 | tRNA pseudouridine synthase B | 4.52e-05 | NA | NA | 0.4772 |
| 6. F | Q8FEF9 | tRNA pseudouridine synthase C | 3.65e-06 | NA | NA | 0.4538 |
| 6. F | B7J0P9 | tRNA pseudouridine synthase B | 2.56e-07 | NA | NA | 0.5108 |
| 6. F | C4K0F2 | tRNA pseudouridine synthase B | 4.72e-07 | NA | NA | 0.4985 |
| 6. F | Q6LWM3 | Probable tRNA pseudouridine synthase B | 1.18e-05 | NA | NA | 0.5215 |
| 6. F | A1R520 | tRNA pseudouridine synthase B | 1.82e-07 | NA | NA | 0.4908 |
| 6. F | A4G0N3 | Probable tRNA pseudouridine synthase B | 1.32e-05 | NA | NA | 0.5149 |
| 6. F | Q044B5 | tRNA pseudouridine synthase B | 1.20e-06 | NA | NA | 0.4512 |
| 6. F | Q5NQ30 | tRNA pseudouridine synthase B | 3.45e-05 | NA | NA | 0.4637 |
| 6. F | B3CM19 | tRNA pseudouridine synthase B | 4.73e-06 | NA | NA | 0.5041 |
| 6. F | Q17QT4 | RNA pseudouridylate synthase domain-containing protein 1 | 2.70e-05 | NA | NA | 0.5041 |
| 6. F | Q2GGA2 | tRNA pseudouridine synthase B | 1.09e-05 | NA | NA | 0.5291 |
| 6. F | Q3YSC6 | tRNA pseudouridine synthase B | 8.64e-06 | NA | NA | 0.496 |
| 6. F | Q0TPS0 | tRNA pseudouridine synthase B | 4.32e-05 | NA | NA | 0.4963 |
| 6. F | Q650L8 | tRNA pseudouridine synthase B | 7.10e-06 | NA | NA | 0.4948 |
| 6. F | Q3ABA1 | tRNA pseudouridine synthase B | 1.98e-07 | NA | NA | 0.5112 |
| 6. F | Q8DBG5 | tRNA pseudouridine synthase C | 3.12e-06 | NA | NA | 0.4725 |
| 6. F | Q5L629 | tRNA pseudouridine synthase B | 7.17e-07 | NA | NA | 0.4962 |
| 6. F | A6UWC6 | Probable tRNA pseudouridine synthase B | 1.04e-05 | NA | NA | 0.5976 |
| 6. F | B1L793 | Probable tRNA pseudouridine synthase B | 1.67e-05 | NA | NA | 0.5804 |
| 6. F | A5GN82 | tRNA pseudouridine synthase B | 6.60e-07 | NA | NA | 0.5153 |
| 6. F | O51743 | tRNA pseudouridine synthase B | 2.51e-07 | NA | NA | 0.5103 |
| 6. F | Q5JJE8 | Probable tRNA pseudouridine synthase B | 2.70e-05 | NA | NA | 0.5906 |
| 6. F | Q3AQK9 | tRNA pseudouridine synthase B | 4.62e-06 | NA | NA | 0.4832 |
| 6. F | Q92HV5 | tRNA pseudouridine synthase B | 3.82e-07 | NA | NA | 0.4889 |
| 6. F | A1RTL7 | Probable tRNA pseudouridine synthase B | 1.48e-05 | NA | NA | 0.59 |
| 6. F | Q8A2U2 | tRNA pseudouridine synthase B | 1.13e-05 | NA | NA | 0.4423 |
| 6. F | B5ZBG4 | tRNA pseudouridine synthase B | 3.84e-06 | NA | NA | 0.4824 |
| 6. F | P59880 | tRNA pseudouridine synthase B | 6.83e-07 | NA | NA | 0.5098 |
| 6. F | O30001 | Probable tRNA pseudouridine synthase B | 1.18e-05 | NA | NA | 0.6011 |
| 6. F | Q9PKU2 | tRNA pseudouridine synthase B | 7.03e-07 | NA | NA | 0.5063 |
| 6. F | Q74IT0 | tRNA pseudouridine synthase B | 1.12e-06 | NA | NA | 0.4548 |
| 6. F | Q5LJ29 | tRNA pseudouridine synthase B | 6.59e-06 | NA | NA | 0.4948 |
| 6. F | A9A8X7 | Probable tRNA pseudouridine synthase B | 1.34e-05 | NA | NA | 0.5218 |
| 6. F | A5VJE2 | tRNA pseudouridine synthase B | 3.18e-05 | NA | NA | 0.4369 |
| 6. F | Q8ZMD5 | tRNA pseudouridine synthase C | 4.74e-06 | NA | NA | 0.4592 |
| 6. F | Q7M9J1 | tRNA pseudouridine synthase B | 1.01e-06 | NA | NA | 0.5022 |
| 6. F | A8GS98 | tRNA pseudouridine synthase B | 3.65e-07 | NA | NA | 0.4927 |
| 6. F | B1AIZ3 | tRNA pseudouridine synthase B | 8.20e-06 | NA | NA | 0.4812 |
| 6. F | A3PEI1 | tRNA pseudouridine synthase B | 1.58e-06 | NA | NA | 0.4695 |
| 6. F | A6VHV2 | Probable tRNA pseudouridine synthase B | 1.28e-05 | NA | NA | 0.5234 |
| 6. F | Q0I7Z1 | tRNA pseudouridine synthase B | 6.68e-07 | NA | NA | 0.5048 |
| 6. F | Q7LWY0 | Probable tRNA pseudouridine synthase B | 3.16e-05 | NA | NA | 0.5877 |
| 6. F | B0BXR2 | tRNA pseudouridine synthase B | 3.39e-07 | NA | NA | 0.4923 |
| 6. F | Q6MTR0 | tRNA pseudouridine synthase B | 4.74e-08 | NA | NA | 0.4961 |
| 6. F | Q8TZ08 | Probable tRNA pseudouridine synthase B | 1.66e-05 | NA | NA | 0.5408 |
| 6. F | P59881 | tRNA pseudouridine synthase B | 2.14e-06 | NA | NA | 0.4844 |
| 6. F | A8G6F8 | tRNA pseudouridine synthase B | 1.43e-06 | NA | NA | 0.4488 |
| 6. F | Q8Z439 | tRNA pseudouridine synthase C | 4.27e-06 | NA | NA | 0.438 |
| 6. F | Q6AJY7 | tRNA pseudouridine synthase B | 1.28e-05 | NA | NA | 0.4452 |
| 6. F | Q9Z8L9 | tRNA pseudouridine synthase B | 6.78e-07 | NA | NA | 0.5045 |
| 6. F | B6YSP4 | Probable tRNA pseudouridine synthase B | 2.71e-05 | NA | NA | 0.5909 |
| 6. F | Q97BU9 | Probable tRNA pseudouridine synthase B | 1.88e-05 | NA | NA | 0.6199 |
| 6. F | Q6MD66 | tRNA pseudouridine synthase B | 9.86e-05 | NA | NA | 0.4634 |
| 6. F | Q975L5 | Probable tRNA pseudouridine synthase B | 2.12e-04 | NA | NA | 0.5625 |
| 6. F | B0B9K2 | tRNA pseudouridine synthase B | 6.69e-07 | NA | NA | 0.5051 |
| 6. F | P59883 | tRNA pseudouridine synthase B | 9.00e-07 | NA | NA | 0.4903 |
| 6. F | C3PNK4 | tRNA pseudouridine synthase B | 2.26e-05 | NA | NA | 0.4788 |
| 6. F | Q2GJV3 | tRNA pseudouridine synthase B | 6.15e-06 | NA | NA | 0.5214 |
| 6. F | Q2KXZ0 | tRNA pseudouridine synthase B | 6.50e-08 | NA | NA | 0.524 |
| 6. F | Q9KTL4 | tRNA pseudouridine synthase C | 1.02e-05 | NA | NA | 0.4616 |
| 6. F | A8GWV0 | tRNA pseudouridine synthase B | 8.85e-08 | NA | NA | 0.4641 |
| 6. F | Q2RJM2 | tRNA pseudouridine synthase B | 2.00e-05 | NA | NA | 0.5052 |
| 6. F | Q18BH7 | tRNA pseudouridine synthase B | 1.74e-05 | NA | NA | 0.4629 |
| 6. F | Q46JB9 | tRNA pseudouridine synthase B | 8.03e-07 | NA | NA | 0.4479 |
| 6. F | Q319E0 | tRNA pseudouridine synthase B | 9.90e-05 | NA | NA | 0.4668 |
| 6. F | Q68WN3 | tRNA pseudouridine synthase B | 7.67e-06 | NA | NA | 0.4815 |
| 6. F | Q9CGH0 | tRNA pseudouridine synthase B | 1.67e-06 | NA | NA | 0.42 |
| 6. F | Q1G9Q1 | tRNA pseudouridine synthase B | 7.40e-07 | NA | NA | 0.4477 |
| 6. F | Q9PQD7 | tRNA pseudouridine synthase B | 8.09e-06 | NA | NA | 0.475 |
| 6. F | Q9HIT4 | Probable tRNA pseudouridine synthase B | 2.10e-05 | NA | NA | 0.6325 |
| 6. F | O84096 | tRNA pseudouridine synthase B | 6.78e-07 | NA | NA | 0.5014 |
| 6. F | A6KZJ9 | tRNA pseudouridine synthase B | 6.69e-06 | NA | NA | 0.4997 |
| 6. F | C3PH13 | tRNA pseudouridine synthase B | 3.73e-07 | NA | NA | 0.487 |
| 6. F | P0AA42 | tRNA pseudouridine synthase C | 3.93e-06 | NA | NA | 0.4478 |
| 6. F | P43930 | Uncharacterized RNA pseudouridine synthase HI_0042 | 1.85e-05 | NA | NA | 0.491 |
| 6. F | Q254H2 | tRNA pseudouridine synthase B | 6.53e-07 | NA | NA | 0.4936 |
| 6. F | A2BY54 | tRNA pseudouridine synthase B | 1.86e-06 | NA | NA | 0.4575 |
| 6. F | Q28C59 | Mitochondrial RNA pseudouridine synthase rpusd4 | 5.06e-04 | NA | NA | 0.5435 |
| 6. F | P60346 | Probable tRNA pseudouridine synthase B | 2.63e-05 | NA | NA | 0.6162 |
| 6. F | O66114 | Uncharacterized RNA pseudouridine synthase ZMO0505 | 1.32e-05 | NA | NA | 0.562 |
| 6. F | A3CMF2 | tRNA pseudouridine synthase B | 3.57e-05 | NA | NA | 0.4774 |
| 6. F | Q87LD3 | Dual-specificity RNA pseudouridine synthase RluA | 8.71e-07 | NA | NA | 0.5447 |
| 6. F | Q895J5 | tRNA pseudouridine synthase B | 2.24e-07 | NA | NA | 0.5058 |
| 6. F | Q8CXU1 | tRNA pseudouridine synthase B | 9.88e-07 | NA | NA | 0.4882 |
| 6. F | A9KNW1 | tRNA pseudouridine synthase B | 3.30e-05 | NA | NA | 0.4608 |
| 6. F | Q9CNF3 | tRNA pseudouridine synthase C | 4.61e-06 | NA | NA | 0.4568 |
| 6. F | Q8DU15 | tRNA pseudouridine synthase B | 2.07e-07 | NA | NA | 0.4362 |
| 6. F | B0BB81 | tRNA pseudouridine synthase B | 7.40e-07 | NA | NA | 0.5054 |
| 6. F | A4QEY6 | tRNA pseudouridine synthase B | 3.12e-07 | NA | NA | 0.4713 |
| 7. B | Q8L960 | Putative ribosomal large subunit pseudouridine synthase SVR1, chloroplastic | 0.00e+00 | NA | 1.67e-21 | NA |