Summary
The literature section presents previous knowledge about this protein. There have been five different efforts to annotate minimal organism genome. The annotations from those efforts are given in the Literature section for completeness.
AVX54727.1
JCVISYN3A_0338
Uncharacterized lipoprotein.
M. mycoides homolog: Q6MTK6.
TIGRfam Classification: 1=Unknown.
Category: Essential.
Statistics
Total GO Annotation: 15
Unique PROST Go: 15
Unique BLAST Go: 0
Unique Foldseek Go: 0
Total Homologs: 19
Unique PROST Homologs: 19
Unique BLAST Homologs: 0
Unique Foldseek Homologs: 0
Structures and Sequence Alignment
The best structural homolog that predicted by 5. P was
Q7M1T6
(Antigenic membrane protein) with a FATCAT P-Value: 0.00541 and RMSD of 3.84 angstrom. The sequence alignment identity is 28.3%.
Structural alignment shown in left. Query protein AVX54727.1 colored as red in alignment, homolog Q7M1T6 colored as blue.
Query protein AVX54727.1 is also shown in right top, homolog Q7M1T6 showed in right bottom. They are colored based on secondary structures.
AVX54727.1 ----------MKKLLTILGSVGLVATSGAFVIACGDKPKMNDAKSIQEEKIDLNKLIKVRD-LGFVSKN----EKEIIKSAFVKQNGLNDPKL-KDKIEV 84 Q7M1T6 MQNQKNQKSLVAKVLVLFAAVALMFV-GVQVFA--D-----D-------KLDLNTL-ECKDALELTAADAADAEK-VVKQWKVQNTSLN-AKVTKDSVKV 82 AVX54727.1 EV---K---TNGSGTSGAGTTAS--TN--GNSSDSAVIEVKNK-TNGNGNVT-K--TVTV----IFDVNNSLKTLVKVTKLKSLPD--NKDETILAAVAK 164 Q7M1T6 AVADNKVTVTPADGDAGKALSGSKILNLVG------VCEL-NKLTLG----TEKKLTLTVKDGKV-DAEAGLKAL-KEAGAK-VPATVNKDD-VTFTVGK 167 AVX54727.1 ANPKSNLDTQKLKIERTDGKVLVKSSDGQTYKDEAELQIESKVGVY--VG-LSLLSVALLAS-SGFIIYRSVKKKKKQM 239 Q7M1T6 ---DDN--ANKVTVKAVDGKTTV---SGQVV---FEFTV-AKTPWYKTVWFLTLVAVVVVAAVAGGVFF-FVKKNKKNK 233
Go Annotations
1. PBF indicates the go terms that are found by both PROST and BLAST and Foldseek.
2. PF indicates the go terms that are found by only PROST and Foldseek.
3. BF indicates the go terms that are found by only BLAST and Foldseek.
4. PB indicates the go terms that are found by both PROST and BLAST.
5. P indicates the go terms that are found by only PROST.
6. F indicates the go terms that are found by only Foldseek.
7. B indicates the go terms that are found by only BLAST.
| Source | GO | Description |
|---|---|---|
| 5. P | GO:0005618 | cell wall |
| 5. P | GO:0009274 | peptidoglycan-based cell wall |
| 5. P | GO:0030492 | hemoglobin binding |
| 5. P | GO:0019864 | IgG binding |
| 5. P | GO:0005886 | plasma membrane |
| 5. P | GO:0031361 | integral component of thylakoid membrane |
| 5. P | GO:0015979 | photosynthesis |
| 5. P | GO:0009055 | electron transfer activity |
| 5. P | GO:0005576 | extracellular region |
| 5. P | GO:0015886 | heme transport |
| 5. P | GO:0071281 | cellular response to iron ion |
| 5. P | GO:0020037 | heme binding |
| 5. P | GO:0005506 | iron ion binding |
| 5. P | GO:0031676 | plasma membrane-derived thylakoid membrane |
| 5. P | GO:0055072 | iron ion homeostasis |
Uniprot GO Annotations
| GO | Description |
|---|---|
| GO:0016020 | membrane |
| GO:0016021 | integral component of membrane |
Homologs
1. PBF indicates the homologs that are found by both PROST and BLAST and Foldseek.
2. PF indicates the homologs that are found by only PROST and Foldseek.
3. BF indicates the homologs that are found by only BLAST and Foldseek.
4. PB indicates the homologs that are found by both PROST and BLAST.
5. P indicates the homologs that are found by only PROST.
6. F indicates the homologs that are found by only Foldseek.
7. B indicates the homologs that are found by only BLAST.
| Source | Homolog | Description | Fatcat Pvalue | PROST Evalue | BLAST Evalue | Foldseek TMScore |
|---|---|---|---|---|---|---|
| 5. P | Q8Y3W5 | Cell wall protein Lmo2714 | 9.62e-02 | 1.49e-04 | NA | NA |
| 5. P | C1JJY5 | Uncharacterized protein 6 | NA | 1.54e-02 | NA | NA |
| 5. P | P0DJ01 | Lipoprotein p35 | 2.11e-01 | 1.19e-02 | NA | NA |
| 5. P | P06654 | Immunoglobulin G-binding protein G | 5.05e-01 | 4.35e-02 | NA | NA |
| 5. P | A3PBI4 | Cytochrome f | 1.67e-01 | 7.75e-03 | NA | NA |
| 5. P | P42549 | Uncharacterized 26.1 kDa protein | NA | 6.70e-05 | NA | NA |
| 5. P | P0DJ00 | Lipoprotein p35 | 2.29e-01 | 2.00e-02 | NA | NA |
| 5. P | A8G3H6 | Cytochrome f | 2.40e-01 | 3.11e-02 | NA | NA |
| 5. P | P94431 | Uncharacterized protein YcnI | 1.45e-01 | 5.06e-04 | NA | NA |
| 5. P | A2BVC3 | Cytochrome f | 2.52e-01 | 3.72e-02 | NA | NA |
| 5. P | Q2G0X4 | Staphylococcal superantigen-like 11 | 3.67e-01 | 4.61e-03 | NA | NA |
| 5. P | A2BPU4 | Cytochrome f | 1.76e-01 | 6.76e-03 | NA | NA |
| 5. P | Q7M1T6 | Antigenic membrane protein | 5.41e-03 | 3.25e-09 | NA | NA |
| 5. P | A0A0H3KEE7 | Superantigen-like protein 11 | 3.30e-01 | 4.61e-03 | NA | NA |
| 5. P | Q9L8P6 | Lipoprotein B | 5.04e-01 | 1.49e-02 | NA | NA |
| 5. P | Q8Y585 | Hemin/hemoglobin-binding protein 1 | 1.03e-01 | 4.95e-04 | NA | NA |
| 5. P | P19215 | Spiralin | 1.46e-02 | 4.40e-05 | NA | NA |
| 5. P | P47341 | Uncharacterized lipoprotein MG095 | 5.65e-01 | 4.90e-02 | NA | NA |
| 5. P | P21625 | Spiralin | 1.07e-02 | 6.06e-05 | NA | NA |