Summary
The literature section presents previous knowledge about this protein. There have been five different efforts to annotate minimal organism genome. The annotations from those efforts are given in the Literature section for completeness.
AVX54786.1
JCVISYN3A_0424
Uncharacterized protein.
M. mycoides homolog: Q6MTC4.
TIGRfam Classification: 1=Unknown.
Category: Essential.
Statistics
Total GO Annotation: 9
Unique PROST Go: 9
Unique BLAST Go: 0
Unique Foldseek Go: 0
Total Homologs: 21
Unique PROST Homologs: 21
Unique BLAST Homologs: 0
Unique Foldseek Homologs: 0
Structures and Sequence Alignment
The best structural homolog that predicted by 5. P was
Q8R3Q6
(Protein MIX23) with a FATCAT P-Value: 5.04e-07 and RMSD of 2.30 angstrom. The sequence alignment identity is 17.1%.
Structural alignment shown in left. Query protein AVX54786.1 colored as red in alignment, homolog Q8R3Q6 colored as blue.
Query protein AVX54786.1 is also shown in right top, homolog Q8R3Q6 showed in right bottom. They are colored based on secondary structures.
AVX54786.1 ----------------------MNWSIKKVSDKKLAVKKDENGSFLNYSKAVNL-AIRMAKK-QKAILEIFNEKDRLIKTYNFDQVLTQ-SELVEKIRTE 75 Q8R3Q6 MAAPSGSVNCEEFAEFQELLKVM----RTIDDR---IVHELNTTVPTASFAGKIDASQTCKQLYESLMAAHVSRDRVIK--N---CIAQTSAVVKSLR-E 87 AVX54786.1 LKLAYAKK----TVAKIELEKHHKKYKKALKSKNNLEKEQLK-QIFKL----AKLNYKNKKRQIKYIKFRYKIAKRNLKDW 147 Q8R3Q6 ER---EKNLDDLTLLK-RLRKEQTKL-KWMQSELNVE-EVVNDRSWKVFNERCRVHFKPPKNE------------------ 144
Go Annotations
1. PBF indicates the go terms that are found by both PROST and BLAST and Foldseek.
2. PF indicates the go terms that are found by only PROST and Foldseek.
3. BF indicates the go terms that are found by only BLAST and Foldseek.
4. PB indicates the go terms that are found by both PROST and BLAST.
5. P indicates the go terms that are found by only PROST.
6. F indicates the go terms that are found by only Foldseek.
7. B indicates the go terms that are found by only BLAST.
| Source | GO | Description |
|---|---|---|
| 5. P | GO:0005758 | mitochondrial intermembrane space |
| 5. P | GO:0006231 | dTMP biosynthetic process |
| 5. P | GO:0050797 | thymidylate synthase (FAD) activity |
| 5. P | GO:0000776 | kinetochore |
| 5. P | GO:0006325 | chromatin organization |
| 5. P | GO:0006235 | dTTP biosynthetic process |
| 5. P | GO:0051301 | cell division |
| 5. P | GO:0051321 | meiotic cell cycle |
| 5. P | GO:0035267 | NuA4 histone acetyltransferase complex |
Uniprot GO Annotations
| GO | Description |
|---|
Homologs
1. PBF indicates the homologs that are found by both PROST and BLAST and Foldseek.
2. PF indicates the homologs that are found by only PROST and Foldseek.
3. BF indicates the homologs that are found by only BLAST and Foldseek.
4. PB indicates the homologs that are found by both PROST and BLAST.
5. P indicates the homologs that are found by only PROST.
6. F indicates the homologs that are found by only Foldseek.
7. B indicates the homologs that are found by only BLAST.
| Source | Homolog | Description | Fatcat Pvalue | PROST Evalue | BLAST Evalue | Foldseek TMScore |
|---|---|---|---|---|---|---|
| 5. P | P29582 | Uncharacterized protein ORF7 | 2.04e-04 | 5.14e-03 | NA | NA |
| 5. P | Q6FJV4 | Chromatin modification-related protein EAF5 | 4.58e-04 | 1.88e-02 | NA | NA |
| 5. P | Q7MIF7 | UPF0325 protein VV2560 | 4.31e-03 | 5.52e-04 | NA | NA |
| 5. P | Q16BB4 | UPF0262 protein RD1_1069 | 2.75e-04 | 1.85e-03 | NA | NA |
| 5. P | Q5UR51 | Uncharacterized protein R566 | NA | 1.12e-03 | NA | NA |
| 5. P | Q5E3D6 | UPF0325 protein VF_1965 | 5.25e-03 | 2.59e-03 | NA | NA |
| 5. P | A7N1Y0 | UPF0325 protein VIBHAR_03240 | 5.63e-03 | 1.13e-02 | NA | NA |
| 5. P | Q6LN21 | UPF0325 protein PBPRA2971 | 6.15e-03 | 2.77e-02 | NA | NA |
| 5. P | P03549 | Aphid transmission protein | NA | 8.17e-03 | NA | NA |
| 5. P | P11335 | Internal scaffolding protein ORF3 | NA | 1.05e-03 | NA | NA |
| 5. P | P0DON7 | Late protein H7 | NA | 8.09e-03 | NA | NA |
| 5. P | O66410 | Uncharacterized protein aq_aa19 | 1.37e-03 | 2.10e-02 | NA | NA |
| 5. P | B1MD42 | Flavin-dependent thymidylate synthase | 2.95e-02 | 1.51e-02 | NA | NA |
| 5. P | Q6CSR8 | Inner kinetochore subunit NKP2 | 6.43e-06 | 4.49e-04 | NA | NA |
| 5. P | P0DON8 | Late protein H7 | NA | 8.09e-03 | NA | NA |
| 5. P | Q8DBG4 | UPF0325 protein VV1_1856 | 7.75e-03 | 5.52e-04 | NA | NA |
| 5. P | Q12493 | Inner kinetochore subunit NKP1 | 5.69e-05 | 2.12e-02 | NA | NA |
| 5. P | B5F9X9 | UPF0325 protein VFMJ11_2099 | 4.96e-03 | 2.59e-03 | NA | NA |
| 5. P | O31922 | SPbeta prophage-derived uncharacterized protein YoqP | 1.89e-04 | 1.85e-05 | NA | NA |
| 5. P | Q8R3Q6 | Protein MIX23 | 5.04e-07 | 2.79e-02 | NA | NA |
| 5. P | Q04628 | Uncharacterized protein PA1545 | 6.01e-05 | 4.54e-02 | NA | NA |