Summary

The literature section presents previous knowledge about this protein. There have been five different efforts to annotate minimal organism genome. The annotations from those efforts are given in the Literature section for completeness.

AVX54807.1
JCVISYN3A_0447

dUTP diphosphatase.
M. mycoides homolog: Q6MTA1.
TIGRfam Classification: 2=Generic.
Category: Essential.

Statistics

Total GO Annotation: 7
Unique PROST Go: 7
Unique BLAST Go: 0
Unique Foldseek Go: 0

Total Homologs: 17
Unique PROST Homologs: 17
Unique BLAST Homologs: 0
Unique Foldseek Homologs: 0

Literature

Danchin and Fang [1]: dUTPase, type 2|phage origin; moonlighting activity
Yang and Tsui [2]: Dimeric dUTPase Dut
Antczak et al. [3]: dUTP diphosphatase
Zhang et al. [4]: GO:0004170|dUTP diphosphatase activity
Bianchi et al. [5]: dut-like DUTPase diphosphatase

Structures and Sequence Alignment

The best structural homolog that predicted by 5. P was Q6VN46 (Myoglobin) with a FATCAT P-Value: 0.000482 and RMSD of 1.77 angstrom. The sequence alignment identity is 21.7%.
Structural alignment shown in left. Query protein AVX54807.1 colored as red in alignment, homolog Q6VN46 colored as blue. Query protein AVX54807.1 is also shown in right top, homolog Q6VN46 showed in right bottom. They are colored based on secondary structures.

  AVX54807.1 MIDNK-TLK-WLSEKQIILDQFIQN---KWN--FKN--DKTL-LDKKLTAFLVELGEYANEERSFKYWSN--KKPSDLEIQLDEYIDGIH-FIIS-VGN- 85
      Q6VN46 MADHDLVLKCW---GAVEAD-YAANGGEVLNRLFKEYPD-TLKLFPKFSG--ISQGDLAGSPAVAAHGATVLKKLGEL---LKA--KGDHAALLKPLANT 88

  AVX54807.1 QINYNFLEFNYNF-LNKESIIDIYFEIISC-LNSFIKENNNTNYSNLLNAFLNICEIKNYTQDQIINAYNIKNEINFQRQNNNY 167
      Q6VN46 HANIHKVALN-NFRLITEVLVKVMAE--KAGLDA---AGQGA-LRRVMDAVIG--DIDGY--------Y--K-EIGFAG----- 147

Go Annotations

1. PBF indicates the go terms that are found by both PROST and BLAST and Foldseek.
2. PF indicates the go terms that are found by only PROST and Foldseek.
3. BF indicates the go terms that are found by only BLAST and Foldseek.
4. PB indicates the go terms that are found by both PROST and BLAST.
5. P indicates the go terms that are found by only PROST.
6. F indicates the go terms that are found by only Foldseek.
7. B indicates the go terms that are found by only BLAST.

Source GO Description
5. P GO:0015671 oxygen transport
5. P GO:0014823 response to activity
5. P GO:0019825 oxygen binding
5. P GO:0001570 vasculogenesis
5. P GO:0048565 digestive tract development
5. P GO:0001666 response to hypoxia
5. P GO:0005344 oxygen carrier activity

Uniprot GO Annotations

GO Description

Homologs

1. PBF indicates the homologs that are found by both PROST and BLAST and Foldseek.
2. PF indicates the homologs that are found by only PROST and Foldseek.
3. BF indicates the homologs that are found by only BLAST and Foldseek.
4. PB indicates the homologs that are found by both PROST and BLAST.
5. P indicates the homologs that are found by only PROST.
6. F indicates the homologs that are found by only Foldseek.
7. B indicates the homologs that are found by only BLAST.

Source Homolog Description Fatcat Pvalue PROST Evalue BLAST Evalue Foldseek TMScore
5. P Q6VN46 Myoglobin 4.82e-04 2.92e-02 NA NA
5. P B4THE2 UPF0149 protein YgfB 1.51e-03 1.82e-02 NA NA
5. P B5QXI6 UPF0149 protein YgfB 1.58e-03 1.82e-02 NA NA
5. P B5FUH3 UPF0149 protein YgfB 1.59e-03 1.82e-02 NA NA
5. P P51714 Uncharacterized 18.2 kDa protein in rep-hol intergenic region NA 1.33e-11 NA NA
5. P B7V5B5 UPF0149 protein PLES_56191 2.26e-03 4.95e-02 NA NA
5. P Q9HTW5 UPF0149 protein PA5225 2.19e-03 4.95e-02 NA NA
5. P A6VDZ9 UPF0149 protein PSPA7_5968 2.19e-03 4.30e-02 NA NA
5. P B5RE20 UPF0149 protein YgfB 1.58e-03 1.82e-02 NA NA
5. P B5F5I5 UPF0149 protein YgfB 1.61e-03 1.82e-02 NA NA
5. P P39789 Uncharacterized protein YpoC 3.18e-03 1.36e-03 NA NA
5. P Q8ZM71 UPF0149 protein YgfB 1.59e-03 1.82e-02 NA NA
5. P C0PY33 UPF0149 protein YgfB 1.59e-03 1.82e-02 NA NA
5. P Q02ED9 UPF0149 protein PA14_69010 2.12e-03 4.95e-02 NA NA
5. P B4TV29 UPF0149 protein YgfB 1.60e-03 1.82e-02 NA NA
5. P Q8Z3W5 UPF0149 protein YgfB 1.59e-03 1.78e-02 NA NA
5. P B4T555 UPF0149 protein YgfB 1.59e-03 1.82e-02 NA NA