Summary

The literature section presents previous knowledge about this protein. There have been five different efforts to annotate minimal organism genome. The annotations from those efforts are given in the Literature section for completeness.

AVX54824.1
JCVISYN3A_0503

Uncharacterized protein.
M. mycoides homolog: Q6MT47.
TIGRfam Classification: 1=Unknown.
Category: Quasiessential.

Statistics

Total GO Annotation: 3
Unique PROST Go: 3
Unique BLAST Go: 0
Unique Foldseek Go: 0

Total Homologs: 3
Unique PROST Homologs: 3
Unique BLAST Homologs: 0
Unique Foldseek Homologs: 0

Literature

Danchin and Fang [1]: NA
Yang and Tsui [2]: 6,7-dimethyl-8-ribityllumazine synthase
Antczak et al. [3]: Hypothetical protein
Zhang et al. [4]: GO:0009279|cell outer membrane
Bianchi et al. [5]: Unclear protein

Structures and Sequence Alignment

The best structural homolog that predicted by 5. P was P22522 (Colicin-V) with a FATCAT P-Value: 0.0336 and RMSD of 1.07 angstrom. The sequence alignment identity is 23.3%.
Structural alignment shown in left. Query protein AVX54824.1 colored as red in alignment, homolog P22522 colored as blue. Query protein AVX54824.1 is also shown in right top, homolog P22522 showed in right bottom. They are colored based on secondary structures.

  AVX54824.1 MKEINLENTKEIIGGA-G--VS---GALINGIAKVVESGFEGVSNLITDIASVGFAFY-QAS--K-NPIKADYKIGNNSFKIDNTKLVDLKIQQAKAQEI 90
      P22522 MRTLTLNELDSVSGGASGRDIAMAIGTL-SG--QFV-AG--GIGAAAGGVA--GGAIYDYASTHKPNPAMSPSGLG-------GT----IK-Q--KPE-- 76

  AVX54824.1 KIPVLEIGNNKNNIKI-NYNDAYNN--DEQISNIYNDFDQNISIFN 133
      P22522 GIPS-EAWNYAAG-RLCNWSP--NNLSDVCL--------------- 103

Go Annotations

1. PBF indicates the go terms that are found by both PROST and BLAST and Foldseek.
2. PF indicates the go terms that are found by only PROST and Foldseek.
3. BF indicates the go terms that are found by only BLAST and Foldseek.
4. PB indicates the go terms that are found by both PROST and BLAST.
5. P indicates the go terms that are found by only PROST.
6. F indicates the go terms that are found by only Foldseek.
7. B indicates the go terms that are found by only BLAST.

Source GO Description
5. P GO:0019835 cytolysis
5. P GO:0042742 defense response to bacterium
5. P GO:0016021 integral component of membrane

Uniprot GO Annotations

GO Description

Homologs

1. PBF indicates the homologs that are found by both PROST and BLAST and Foldseek.
2. PF indicates the homologs that are found by only PROST and Foldseek.
3. BF indicates the homologs that are found by only BLAST and Foldseek.
4. PB indicates the homologs that are found by both PROST and BLAST.
5. P indicates the homologs that are found by only PROST.
6. F indicates the homologs that are found by only Foldseek.
7. B indicates the homologs that are found by only BLAST.

Source Homolog Description Fatcat Pvalue PROST Evalue BLAST Evalue Foldseek TMScore
5. P Q49403 Uncharacterized protein MG220 6.77e-03 3.75e-05 NA NA
5. P P75468 Uncharacterized protein MG220 homolog 2.75e-02 1.86e-06 NA NA
5. P P22522 Colicin-V 3.36e-02 1.49e-03 NA NA