Summary

The literature section presents previous knowledge about this protein. There have been five different efforts to annotate minimal organism genome. The annotations from those efforts are given in the Literature section for completeness.

AVX54863.1
JCVISYN3A_0599

Uncharacterized protein.
M. mycoides homolog: Q6MU48.
TIGRfam Classification: 1=Unknown.
Category: Nonessential.

Statistics

Total GO Annotation: 48
Unique PROST Go: 48
Unique BLAST Go: 0
Unique Foldseek Go: 0

Total Homologs: 126
Unique PROST Homologs: 126
Unique BLAST Homologs: 0
Unique Foldseek Homologs: 0

Literature

Danchin and Fang [1]: NA
Yang and Tsui [2]: NA
Antczak et al. [3]: Hypothetical protein
Zhang et al. [4]: GO:0006810|transport
Bianchi et al. [5]: Unclear

Structures and Sequence Alignment

The best structural homolog that predicted by 5. P was P14663 (Bactericidin B-3) with a FATCAT P-Value: 0.000721 and RMSD of 1.53 angstrom. The sequence alignment identity is 16.0%.
Structural alignment shown in left. Query protein AVX54863.1 colored as red in alignment, homolog P14663 colored as blue. Query protein AVX54863.1 is also shown in right top, homolog P14663 showed in right bottom. They are colored based on secondary structures. 

  AVX54863.1 MKDNNSRFIPWDSISEEELLENAKRKIDDT-FNDKEFVALLKKLEKM--- 46
      P14663 ----------WNPFKE---LERAGQRVRDAIISAGPAVATVGQAAAIARG 37

Go Annotations

1. PBF indicates the go terms that are found by both PROST and BLAST and Foldseek.
2. PF indicates the go terms that are found by only PROST and Foldseek.
3. BF indicates the go terms that are found by only BLAST and Foldseek.
4. PB indicates the go terms that are found by both PROST and BLAST.
5. P indicates the go terms that are found by only PROST.
6. F indicates the go terms that are found by only Foldseek.
7. B indicates the go terms that are found by only BLAST.

Source GO Description
5. P GO:0060348 bone development
5. P GO:0070490 protein pupylation
5. P GO:0031214 biomineral tissue development
5. P GO:0034709 methylosome
5. P GO:0005682 U5 snRNP
5. P GO:0050829 defense response to Gram-negative bacterium
5. P GO:0090540 bacterial cellulose biosynthetic process
5. P GO:0009306 protein secretion
5. P GO:0042601 endospore-forming forespore
5. P GO:0045177 apical part of cell
5. P GO:0019731 antibacterial humoral response
5. P GO:0008147 structural constituent of bone
5. P GO:0046848 hydroxyapatite binding
5. P GO:1905048 regulation of metallopeptidase activity
5. P GO:0031397 negative regulation of protein ubiquitination
5. P GO:0030436 asexual sporulation
5. P GO:0030500 regulation of bone mineralization
5. P GO:0005179 hormone activity
5. P GO:0005509 calcium ion binding
5. P GO:0050830 defense response to Gram-positive bacterium
5. P GO:2000147 positive regulation of cell motility
5. P GO:0030032 lamellipodium assembly
5. P GO:0005686 U2 snRNP
5. P GO:1900191 negative regulation of single-species biofilm formation
5. P GO:0070628 proteasome binding
5. P GO:0034719 SMN-Sm protein complex
5. P GO:0005845 mRNA cap binding complex
5. P GO:0031386 protein tag
5. P GO:0005687 U4 snRNP
5. P GO:1900076 regulation of cellular response to insulin stimulus
5. P GO:0008017 microtubule binding
5. P GO:0030435 sporulation resulting in formation of a cellular spore
5. P GO:0005576 extracellular region
5. P GO:0002553 histamine secretion by mast cell
5. P GO:0031529 ruffle organization
5. P GO:0033732 pyrroloquinoline-quinone synthase activity
5. P GO:0005856 cytoskeleton
5. P GO:0061564 axon development
5. P GO:0010596 negative regulation of endothelial cell migration
5. P GO:0048675 axon extension
5. P GO:0019941 modification-dependent protein catabolic process
5. P GO:0010498 proteasomal protein catabolic process
5. P GO:0032571 response to vitamin K
5. P GO:0034715 pICln-Sm protein complex
5. P GO:0098672 inhibition of host CRISPR-cas system by virus
5. P GO:0043306 positive regulation of mast cell degranulation
5. P GO:0001649 osteoblast differentiation
5. P GO:0006508 proteolysis

Uniprot GO Annotations

GO Description

Homologs

1. PBF indicates the homologs that are found by both PROST and BLAST and Foldseek.
2. PF indicates the homologs that are found by only PROST and Foldseek.
3. BF indicates the homologs that are found by only BLAST and Foldseek.
4. PB indicates the homologs that are found by both PROST and BLAST.
5. P indicates the homologs that are found by only PROST.
6. F indicates the homologs that are found by only Foldseek.
7. B indicates the homologs that are found by only BLAST.

Source Homolog Description Fatcat Pvalue PROST Evalue BLAST Evalue Foldseek TMScore
5. P P18107 Pancreatic hormone 1.18e-02 6.17e-03 NA NA
5. P P50519 Heat shock protein hsp9 1.85e-02 7.50e-05 NA NA
5. P Q8DSY5 UPF0346 protein SMU_1621c 3.59e-02 1.35e-02 NA NA
5. P P0ACE3 Hemolysin expression-modulating protein Hha 8.61e-02 3.66e-02 NA NA
5. P O28816 Uncharacterized protein AF_1456 2.08e-02 7.12e-03 NA NA
5. P P21344 Transcriptional regulatory protein SenS 1.55e-02 4.44e-04 NA NA
5. P P85091 Cytoplasmic FMR1-interacting protein 1 (Fragments) 1.77e-02 4.01e-02 NA NA
5. P O32014 Uncharacterized protein YqzH 3.15e-02 5.14e-03 NA NA
5. P Q914L8 Uncharacterized protein 12 NA 2.73e-03 NA NA
5. P Q834H2 UPF0346 protein EF_1680 1.48e-01 4.27e-05 NA NA
5. P P0ADJ4 Protein YhjR 2.47e-02 8.06e-03 NA NA
5. P P41538 Diuretic hormone 1.40e-02 3.47e-02 NA NA
5. P Q9KTN0 UPF0253 protein VC_0872 1.36e-02 4.16e-03 NA NA
5. P Q88VB7 UPF0223 protein lp_2149 7.11e-02 5.00e-03 NA NA
5. P B5FBB5 UPF0253 protein VFMJ11_0680 1.84e-02 5.61e-03 NA NA
5. P Q9PQZ3 Uncharacterized protein UU151 5.41e-02 1.56e-03 NA NA
5. P Q8NQE0 Prokaryotic ubiquitin-like protein Pup 6.26e-02 1.59e-03 NA NA
5. P Q54N95 Putative uncharacterized protein DDB_G0285383 2.37e-02 2.58e-03 NA NA
5. P G2TRL3 Ribosome assembly protein 3 9.21e-04 8.62e-03 NA NA
5. P Q8DBI1 UPF0253 protein VV1_1836 1.35e-02 8.38e-03 NA NA
5. P O28966 Uncharacterized protein AF_1303 1.10e-01 2.28e-02 NA NA
5. P Q03Y50 UPF0346 protein LEUM_0763 1.77e-02 3.90e-02 NA NA
5. P Q3V4T3 Uncharacterized protein ORF48 NA 5.39e-04 NA NA
5. P O34503 Uncharacterized protein YtzD 5.78e-02 1.83e-03 NA NA
5. P P67800 Diuretic hormone 1.24e-02 8.19e-06 NA NA
5. P Q52278 Protein KleA 7.04e-02 3.02e-03 NA NA
5. P B5F8H5 UPF0270 protein YheU 5.14e-03 3.14e-02 NA NA
5. P P0C8M3 Small vasohibin-binding protein 6.53e-02 1.62e-02 NA NA
5. P P14662 Bactericidin B-2 1.39e-03 1.88e-02 NA NA
5. P C1CDU3 UPF0346 protein SPJ_0886 3.20e-02 9.92e-04 NA NA
5. P O28340 Uncharacterized protein AF_1939 2.64e-02 2.47e-02 NA NA
5. P Q99LQ4 Small vasohibin-binding protein 4.45e-02 2.16e-02 NA NA
5. P Q47NZ3 Prokaryotic ubiquitin-like protein Pup 4.28e-02 1.84e-03 NA NA
5. P A5F359 UPF0253 protein VC0395_A0398/VC395_0888 1.35e-02 4.16e-03 NA NA
5. P A4VVZ9 UPF0346 protein SSU05_1322 1.64e-01 2.41e-02 NA NA
5. P C4LIL0 Prokaryotic ubiquitin-like protein Pup 5.53e-02 1.53e-05 NA NA
5. P P20329 Uncharacterized gene 6.5 protein NA 1.57e-02 NA NA
5. P C0H446 Uncharacterized protein YpzI 4.11e-01 6.00e-03 NA NA
5. P P86315 Osteocalcin 9.25e-02 2.79e-02 NA NA
5. P P35087 Phycobilisome degradation protein NblA 7.35e-03 5.25e-05 NA NA
5. P P02821 Osteocalcin 8.94e-02 2.10e-02 NA NA
5. P C3LTC2 UPF0253 protein VCM66_0829 1.39e-02 4.16e-03 NA NA
5. P A7Z2M2 Small, acid-soluble spore protein K 6.85e-01 5.09e-03 NA NA
5. P B2VEZ9 Probable Fe(2+)-trafficking protein 7.62e-02 2.79e-02 NA NA
5. P Q828J0 Prokaryotic ubiquitin-like protein Pup 9.79e-02 4.47e-02 NA NA
5. P O31572 Uncharacterized protein YfhD 3.63e-03 4.98e-02 NA NA
5. P P13313 Uncharacterized 10.9 kDa protein in regB-denV intergenic region NA 2.71e-02 NA NA
5. P Q9PQZ7 Uncharacterized protein UU147 8.64e-03 3.87e-08 NA NA
5. P Q7MIE3 UPF0253 protein VV2574 1.36e-02 8.38e-03 NA NA
5. P B8ZRF2 Prokaryotic ubiquitin-like protein Pup 3.99e-02 1.03e-02 NA NA
5. P P14112 Accessory recombination function protein NA 3.76e-02 NA NA
5. P P47439 50S ribosomal protein L35 6.88e-02 1.54e-02 NA NA
5. P Q60262 Uncharacterized protein MJECL05 6.23e-02 8.38e-03 NA NA
5. P O28121 Uncharacterized protein AF_2161 6.67e-02 7.25e-04 NA NA
5. P Q58552 Uncharacterized protein MJ1152 1.30e-02 8.54e-03 NA NA
5. P A7Z2G8 UPF0435 protein RBAM_008100 1.89e-02 7.32e-04 NA NA
5. P P65641 Protein bdm homolog 1.46e-03 5.29e-03 NA NA
5. P P0ACE6 Hemolysin expression-modulating protein Hha 8.49e-02 3.66e-02 NA NA
5. P P96609 Uncharacterized protein YdbN 1.22e-02 2.36e-02 NA NA
5. P Q8FTE5 Prokaryotic ubiquitin-like protein Pup 5.02e-02 2.84e-04 NA NA
5. P Q8MN49 Putative uncharacterized protein DDB_G0277461 6.06e-02 6.62e-04 NA NA
5. P A8M2A2 Prokaryotic ubiquitin-like protein Pup 4.18e-02 4.41e-03 NA NA
5. P O57414 Rho GTPase-activating protein 6 (Fragment) 1.51e-03 4.36e-03 NA NA
5. P P83005 Osteocalcin 8.82e-02 4.35e-04 NA NA
5. P Q29329 Small nuclear ribonucleoprotein Sm D2 (Fragment) NA 3.60e-03 NA NA
5. P Q7WY58 Small, acid-soluble spore protein J 4.89e-03 1.99e-04 NA NA
5. P Q38661 Uncharacterized 5.8 kDa protein NA 5.90e-06 NA NA
5. P Q4KLG3 Small vasohibin-binding protein 5.00e-02 2.16e-02 NA NA
5. P Q70LD3 Uncharacterized protein ORF65 NA 7.06e-03 NA NA
5. P A4QE81 Prokaryotic ubiquitin-like protein Pup 4.81e-02 1.59e-03 NA NA
5. P P85054 Esculentin-1SEb 1.58e-02 1.42e-03 NA NA
5. P P0ACE4 Hemolysin expression-modulating protein Hha 8.55e-02 3.66e-02 NA NA
5. P C1CRV1 UPF0346 protein SPT_1257 3.77e-02 9.92e-04 NA NA
5. P P0ACE5 Hemolysin expression-modulating protein Hha 8.61e-02 3.66e-02 NA NA
5. P P67801 Diuretic hormone 3.01e-02 8.19e-06 NA NA
5. P P65642 Protein bdm homolog 1.53e-03 5.29e-03 NA NA
5. P A4IKI9 Small, acid-soluble spore protein K 1.71e-01 1.56e-03 NA NA
5. P B7VIT4 UPF0253 protein VS_2370 1.46e-02 1.40e-03 NA NA
5. P A4W2A7 UPF0346 protein SSU98_1338 2.18e-01 2.41e-02 NA NA
5. P Q57490 Methylmalonyl-CoA decarboxylase subunit epsilon 1.20e-01 3.00e-02 NA NA
5. P P86313 Osteocalcin 9.35e-02 2.79e-02 NA NA
5. P P07543 Protein virE1 6.87e-02 2.53e-03 NA NA
5. P O29306 Uncharacterized protein AF_0956 1.32e-02 2.97e-02 NA NA
5. P C0H418 Uncharacterized protein YnzL 1.41e-02 1.95e-04 NA NA
5. P Q3V4T4 Uncharacterized protein ORF59a NA 3.76e-02 NA NA
5. P Q9EXD3 Uncharacterized protein MPN_377 3.58e-02 8.30e-07 NA NA
5. P P56338 Photosystem II reaction center protein J 2.17e-02 1.04e-02 NA NA
5. P Q9ZBE0 Prokaryotic ubiquitin-like protein Pup 5.84e-02 1.03e-02 NA NA
5. P O34605 SPbeta prophage-derived uncharacterized protein YopM 5.04e-02 2.73e-05 NA NA
5. P Q5E739 UPF0253 protein VF_0662 1.84e-02 1.00e-03 NA NA
5. P Q9PQ73 Uncharacterized protein UU416 1.51e-01 4.44e-04 NA NA
5. P Q7PNC0 Translation machinery-associated protein 7 homolog 7.58e-02 6.17e-03 NA NA
5. P C5D5S3 Small, acid-soluble spore protein K 6.98e-02 2.76e-03 NA NA
5. P A0A1B0GVZ2 Protein FAM240B 1.28e-02 1.46e-02 NA NA
5. P C0H3S3 Uncharacterized protein YwzD 1.41e-02 3.69e-04 NA NA
5. P Q65MA1 Small, acid-soluble spore protein K 7.33e-01 1.96e-03 NA NA
5. P A3CPA0 UPF0346 protein SSA_1617 4.55e-02 1.20e-02 NA NA
5. P Q5SY13 Putative uncharacterized protein encoded by COL5A1-AS1 4.42e-02 1.68e-04 NA NA
5. P Q73YW7 Prokaryotic ubiquitin-like protein Pup 5.14e-02 3.25e-04 NA NA
5. P P48447 Uncharacterized protein ycf18 NA 7.62e-03 NA NA
5. P P20563 Uncharacterized 7.8 kDa protein NA 1.20e-02 NA NA
5. P P82373 Diuretic hormone class 1 2.25e-02 8.62e-03 NA NA
5. P P01145 Urotensin-1 9.96e-03 8.87e-03 NA NA
5. P P71066 Uncharacterized protein YvfG 3.98e-02 4.85e-02 NA NA
5. P Q9K4V1 Glutamine synthetase translation inhibitor 1.53e-02 7.18e-04 NA NA
5. P P86314 Osteocalcin 9.33e-02 2.79e-02 NA NA
5. P P39427 Uncharacterized 8.1 kDa protein in modB-mrh intergenic region NA 1.95e-06 NA NA
5. P A7Z570 Small, acid-soluble spore protein N 6.18e-01 2.20e-02 NA NA
5. P Q6B8L8 Putative DNA-directed RNA polymerase subunit omega 2.90e-03 4.59e-02 NA NA
5. P Q50438 Pyrroloquinoline-quinone synthase (Fragment) 3.23e-02 3.77e-03 NA NA
5. P P85059 Esculentin-1SEa 2.51e-02 4.41e-03 NA NA
5. P Q9ZB91 50S ribosomal protein L34 8.75e-02 6.99e-03 NA NA
5. P A7N1W2 UPF0253 protein VIBHAR_03255 1.72e-02 1.52e-02 NA NA
5. P P14663 Bactericidin B-3 7.21e-04 5.83e-03 NA NA
5. P P0ADJ3 Protein YhjR 3.35e-02 8.06e-03 NA NA
5. P M1YW29 Prokaryotic ubiquitin-like protein UBact 3.82e-01 1.77e-03 NA NA
5. P P86291 Bacteriocin 3.11e-01 8.72e-05 NA NA
5. P Q6TM71 Anti-CRISPR protein 31 NA 1.64e-03 NA NA
5. P A0A023IWK5 MSDIN-like toxin proprotein 2 2.71e-02 2.79e-03 NA NA
5. P P13328 Uncharacterized 7.3 kDa protein in mobB-Gp55 intergenic region NA 2.18e-02 NA NA
5. P O31870 SPbeta prophage-derived uncharacterized protein YotE 8.70e-04 2.24e-02 NA NA
5. P Q5YUX1 Prokaryotic ubiquitin-like protein Pup 3.35e-02 4.59e-02 NA NA
5. P A4FBY0 Prokaryotic ubiquitin-like protein Pup 1 4.65e-02 1.35e-03 NA NA
5. P P0C225 Osteocalcin 9.71e-02 4.16e-02 NA NA
5. P A0QFB4 Prokaryotic ubiquitin-like protein Pup 5.80e-02 3.25e-04 NA NA
5. P P73890 Phycobilisome degradation protein NblA homolog 2 8.57e-03 2.93e-04 NA NA