Results | PROST

Summary

The literature section presents previous knowledge about this protein. There have been five different efforts to annotate minimal organism genome. The annotations from those efforts are given in the Literature section for completeness.

AVX54879.1

JCVISYN3A_0617

Fatty acid binding protein.
M. mycoides homolog: Q6MSS9.
TIGRfam Classification: 3=Putative.
Category: Quasiessential.

Statistics

Total GO Annotation: 20
Unique PROST Go: 5
Unique BLAST Go: 0
Unique Foldseek Go: 14

Total Homologs: 157
Unique PROST Homologs: 38
Unique BLAST Homologs: 0
Unique Foldseek Homologs: 41

Literature

Danchin and Fang [1]: NA
Yang and Tsui [2]: NA
Antczak et al. [3]: DegV family protein
Zhang et al. [4]: GO:0008289|lipid binding
Bianchi et al. [5]: NA

Structures and Sequence Alignment

The best structural homolog that predicted by 1. PBF was Q97QT7 (DegV domain-containing protein SP_1112) with a FATCAT P-Value: 0 and RMSD of 3.14 angstrom. The sequence alignment identity is 24.2%.
Structural alignment shown in left. Query protein AVX54879.1 colored as red in alignment, homolog Q97QT7 colored as blue. Query protein AVX54879.1 is also shown in right top, homolog Q97QT7 showed in right bottom. They are colored based on secondary structures.

  AVX54879.1 M-KFGILVDSAAVYDPAEFKNTIID--VIPLHIVFPN---NDEYLDIKNIVEQEKILEKVSMGE--NI-KTSQASP-GELEKKYDELLEQYEHIIHIPIT 90
      Q97QT7 MTKIKIVTDSSVTIEPELVKQ--LDITIVPLSVMIDNVVYSDA--DLK---EEGKFL-QL-MQESKNLPKTSQ-PPVGVFAEIFEDLCKDGGQILAIHMS 90

  AVX54879.1 NNLSSML----QTATLVSQDEKYKDKITVYQNN--DLAAQGIALTALSLAKAIKSNK-IKTAQQAIDFIENFKEKVLIAIIPGDLKKLSNGG---RAKGV 180
      Q97QT7 HALSGTVEAARQGASLSTAD------VTVVDSSFTD---QALKFQVVEAAKLAQEGKDMEAILSHVEEVKNHTE-LYIGV--STLENLVKGGRISRVTGL 178

  AVX54879.1 ITTVLNLLKTKLLIIWAKE----P--KKEAIGR---TYNSLIEKLIKNLSNKFKKNKYKLYFLSTPLTSSKTVEIVKQILSD--EK-INFVH-GNVPNIY 267
      Q97QT7 LSSLLN-IRA---VMQMKDHELQPMVK----GRGTKTFKKWLDELITSLSERAVA---EIG-ISYSGSDDWAKE-MKESLQAYVEKPISVLETGSI--IQ 263

  AVX54879.1 TIHAGVETIGFVAIEE-- 283
      Q97QT7 T-HTG-ENAWAILIRYHS 279

Go Annotations

1. PBF indicates the go terms that are found by both PROST and BLAST and Foldseek.
2. PF indicates the go terms that are found by only PROST and Foldseek.
3. BF indicates the go terms that are found by only BLAST and Foldseek.
4. PB indicates the go terms that are found by both PROST and BLAST.
5. P indicates the go terms that are found by only PROST.
6. F indicates the go terms that are found by only Foldseek.
7. B indicates the go terms that are found by only BLAST.

Source	GO	Description
1. PBF	GO:0008289	lipid binding
5. P	GO:0047661	amino-acid racemase activity
5. P	GO:0009252	peptidoglycan biosynthetic process
5. P	GO:0008881	glutamate racemase activity
5. P	GO:0071555	cell wall organization
5. P	GO:0008360	regulation of cell shape
6. F	GO:0000917	division septum assembly
6. F	GO:0032153	cell division site
6. F	GO:0051258	protein polymerization
6. F	GO:0004371	glycerone kinase activity
6. F	GO:0019200	carbohydrate kinase activity
6. F	GO:0019563	glycerol catabolic process
6. F	GO:0047324	phosphoenolpyruvate-glycerone phosphotransferase activity
6. F	GO:0003924	GTPase activity
6. F	GO:0043093	FtsZ-dependent cytokinesis
6. F	GO:0005525	GTP binding
6. F	GO:0006071	glycerol metabolic process
6. F	GO:0019588	anaerobic glycerol catabolic process
6. F	GO:0009758	carbohydrate utilization
6. F	GO:0071322	cellular response to carbohydrate stimulus

Uniprot GO Annotations

GO	Description
GO:0008289	lipid binding

Homologs

1. PBF indicates the homologs that are found by both PROST and BLAST and Foldseek.
2. PF indicates the homologs that are found by only PROST and Foldseek.
3. BF indicates the homologs that are found by only BLAST and Foldseek.
4. PB indicates the homologs that are found by both PROST and BLAST.
5. P indicates the homologs that are found by only PROST.
6. F indicates the homologs that are found by only Foldseek.
7. B indicates the homologs that are found by only BLAST.

Source	Homolog	Description	Fatcat Pvalue	PROST Evalue	BLAST Evalue	Foldseek TMScore
1. PBF	Q98QK2	DegV domain-containing protein MYPU_3590	0.00e+00	9.35e-45	3.20e-05	0.8183
1. PBF	Q97E32	DegV domain-containing protein CA_C3284	0.00e+00	3.54e-54	0.005	0.8396
1. PBF	P0DA58	DegV domain-containing protein SpyM3_1667	0.00e+00	6.49e-50	4.72e-04	0.832
1. PBF	Q8R9U5	DegV domain-containing protein TTE1491	0.00e+00	9.12e-53	0.021	0.8439
1. PBF	Q5HHS1	DegV domain-containing protein SACOL0812	0.00e+00	2.00e-49	1.72e-05	0.8452
1. PBF	Q8XKT3	DegV domain-containing protein CPE1310	0.00e+00	2.19e-56	0.001	0.8047
1. PBF	Q97QT7	DegV domain-containing protein SP_1112	0.00e+00	2.19e-56	0.002	0.8481
1. PBF	P0A0N1	DegV domain-containing protein SA0704	0.00e+00	8.26e-50	1.60e-05	0.8452
1. PBF	Q6GB81	DegV domain-containing protein SAS0714	0.00e+00	2.00e-49	1.72e-05	0.8452
1. PBF	P75312	DegV domain-containing protein MG326 homolog	0.00e+00	1.39e-52	1.87e-08	0.8484
1. PBF	Q6G9D6	DegV domain-containing protein SAS1368	0.00e+00	1.16e-57	3.95e-05	0.8669
1. PBF	Q6GIP2	DegV domain-containing protein SAR0803	0.00e+00	2.00e-49	1.72e-05	0.8451
1. PBF	P47568	DegV domain-containing protein MG326	0.00e+00	4.22e-55	3.97e-09	0.8223
1. PBF	Q5X9X0	DegV domain-containing protein M6_Spy1658	0.00e+00	6.89e-51	2.84e-04	0.8201
1. PBF	Q9RSY3	DegV domain-containing protein DR_1986	0.00e+00	1.50e-56	8.95e-09	0.8751
1. PBF	Q6GGY2	DegV domain-containing protein SAR1438	0.00e+00	1.94e-57	2.26e-05	0.8812
1. PBF	Q97IL6	DegV domain-containing protein CA_C1624	0.00e+00	6.30e-55	3.82e-05	0.8663
1. PBF	Q5HFZ8	DegV domain-containing protein SACOL1460	0.00e+00	1.16e-57	3.95e-05	0.8772
1. PBF	P32436	Protein DegV	0.00e+00	6.97e-55	4.64e-09	0.8523
1. PBF	Q8XNM9	DegV domain-containing protein CPE0304	0.00e+00	3.94e-59	4.13e-05	0.8465
1. PBF	Q98PF7	DegV domain-containing protein MYPU_7660	0.00e+00	4.97e-59	6.31e-07	0.8786
1. PBF	P47688	DegV domain-containing protein MG450	0.00e+00	4.65e-38	4.32e-05	0.8015
1. PBF	P0DA59	DegV domain-containing protein SPs1668	0.00e+00	6.49e-50	4.72e-04	0.823
1. PBF	Q97KH1	DegV domain-containing protein CA_C0948	0.00e+00	1.16e-59	1.02e-06	0.8553
1. PBF	Q9X1H9	Fatty acid-binding protein TM_1468	0.00e+00	1.27e-54	2.48e-05	0.8512
1. PBF	P75127	DegV domain-containing protein MG450 homolog	0.00e+00	7.45e-42	9.21e-08	0.8323
1. PBF	P70945	DegV domain-containing protein YitS	0.00e+00	1.88e-48	1.97e-07	0.8556
1. PBF	Q8NXM4	DegV domain-containing protein MW0711	0.00e+00	2.00e-49	1.72e-05	0.8453
1. PBF	Q8DPT4	DegV domain-containing protein spr1019	0.00e+00	1.43e-55	0.003	0.8293
1. PBF	P67374	DegV domain-containing protein SPy_1936/M5005_Spy1650	0.00e+00	6.89e-51	2.84e-04	0.82
1. PBF	Q8XHH5	DegV domain-containing protein CPE2509	0.00e+00	2.43e-51	0.001	0.8655
1. PBF	P67375	DegV domain-containing protein spyM18_2003	0.00e+00	6.89e-51	2.84e-04	0.8219
1. PBF	Q9PPV5	DegV domain-containing protein UU535	0.00e+00	5.42e-47	3.91e-07	0.8645
1. PBF	P67370	DegV domain-containing protein SAV1425	0.00e+00	4.37e-58	3.11e-04	0.8809
1. PBF	P0A0N0	DegV domain-containing protein SAV0749	0.00e+00	8.26e-50	1.60e-05	0.8454
1. PBF	Q9K6U8	DegV domain-containing protein BH3627	0.00e+00	2.83e-54	0.004	0.8029
1. PBF	P67371	DegV domain-containing protein SA1258	0.00e+00	4.37e-58	3.11e-04	0.8774
1. PBF	Q8NWR0	DegV domain-containing protein MW1315	0.00e+00	1.16e-57	3.95e-05	0.8778
1. PBF	P0A0N2	DegV domain-containing protein	0.00e+00	8.26e-50	1.60e-05	0.8453
2. PF	Q5XCN8	DegV domain-containing protein M6_Spy0690	0.00e+00	3.13e-54	NA	0.8509
2. PF	P0DA55	DegV domain-containing protein SPs0713	0.00e+00	7.03e-56	NA	0.8377
2. PF	Q9CI68	DegV domain-containing protein YejH	0.00e+00	1.02e-54	NA	0.8316
2. PF	Q9A0A6	DegV domain-containing protein SPy_0865/M5005_Spy0672	0.00e+00	1.83e-53	NA	0.85
2. PF	Q9RT62	DegV domain-containing protein DR_1903	0.00e+00	4.51e-49	NA	0.8423
2. PF	Q8DP17	DegV domain-containing protein spr1415	0.00e+00	2.36e-55	NA	0.833
2. PF	Q9RDL7	DegV domain-containing protein SCO2569	0.00e+00	8.25e-47	NA	0.8479
2. PF	P0DA54	DegV domain-containing protein SpyM3_1149	0.00e+00	7.03e-56	NA	0.8386
2. PF	Q9CFB9	DegV domain-containing protein YqaC	0.00e+00	4.51e-49	NA	0.8225
2. PF	Q99YH7	DegV domain-containing protein SPy_1698/M5005_Spy1391	1.11e-16	1.51e-46	NA	0.8097
2. PF	Q9CEH0	DegV domain-containing protein YteA	0.00e+00	7.48e-54	NA	0.8444
2. PF	Q4L2X1	DegV domain-containing protein	1.11e-16	1.31e-42	NA	0.8037
2. PF	Q9RX15	DegV domain-containing protein DR_0500	0.00e+00	6.56e-48	NA	0.8163
2. PF	Q92AE5	DegV domain-containing protein lin1977	0.00e+00	3.33e-62	NA	0.8389
2. PF	Q9X1U4	DegV domain-containing protein TM_1608	4.46e-13	6.66e-04	NA	0.7543
2. PF	Q8NN60	DegV domain-containing protein Cgl2349/cg2579	0.00e+00	1.31e-35	NA	0.8239
2. PF	Q8NZW1	DegV domain-containing protein spyM18_1709	1.11e-16	1.78e-46	NA	0.8086
2. PF	P67373	DegV domain-containing protein spyM18_1511	0.00e+00	7.78e-56	NA	0.8377
2. PF	P0DA52	DegV domain-containing protein SpyM3_0586	0.00e+00	3.66e-53	NA	0.8494
2. PF	Q8DQI6	DegV domain-containing protein spr0652	1.11e-16	3.98e-41	NA	0.781
2. PF	Q5XB32	DegV domain-containing protein M6_Spy1246	0.00e+00	7.78e-56	NA	0.8384
2. PF	Q97RQ6	DegV domain-containing protein SP_0742	1.11e-16	3.98e-41	NA	0.7825
2. PF	P9WP04	DegV domain-containing protein MT2490	0.00e+00	2.76e-54	NA	0.8232
2. PF	P0DA53	DegV domain-containing protein SPs1267	0.00e+00	3.66e-53	NA	0.8508
2. PF	Q97PP6	DegV domain-containing protein SP_1557	0.00e+00	1.79e-55	NA	0.8281
2. PF	Q8XPD7	DegV domain-containing protein CPE0026	0.00e+00	1.12e-46	NA	0.8412
2. PF	P0DA56	DegV domain-containing protein SpyM3_1478	1.11e-16	2.04e-46	NA	0.8066
2. PF	Q8PGV3	DegV domain-containing protein XAC3508	0.00e+00	3.59e-35	NA	0.7851
2. PF	P67369	DegV domain-containing protein Mb2440c	0.00e+00	2.76e-54	NA	0.8242
2. PF	Q8P1E4	DegV domain-containing protein spyM18_0926	0.00e+00	3.13e-54	NA	0.8537
2. PF	P67372	DegV domain-containing protein SPy_1493/M5005_Spy1226	0.00e+00	7.78e-56	NA	0.8332
2. PF	Q927X9	DegV domain-containing protein lin2658	0.00e+00	2.77e-57	NA	0.8343
2. PF	P0DA57	DegV domain-containing protein SPs0389	2.22e-16	2.04e-46	NA	0.8047
2. PF	Q8Y4D5	DegV domain-containing protein lmo2514	0.00e+00	1.83e-56	NA	0.8076
2. PF	Q8Y637	DegV domain-containing protein lmo1863	0.00e+00	2.55e-62	NA	0.8543
2. PF	Q8P5F9	DegV domain-containing protein XCC3382	0.00e+00	2.85e-38	NA	0.7861
2. PF	Q5XAI8	DegV domain-containing protein M6_Spy1440	1.11e-16	2.04e-46	NA	0.804
2. PF	Q97L61	DegV domain-containing protein CA_C0701	0.00e+00	4.90e-55	NA	0.8023
3. BF	Q9PQV3	DegV domain-containing protein UU190	2.22e-16	NA	2.27e-05	0.7958
5. P	B7MR95	Glutamate racemase	1.08e-01	2.47e-02	NA	NA
5. P	B7LA65	Glutamate racemase	1.07e-01	3.78e-02	NA	NA
5. P	P63634	Glutamate racemase	1.07e-01	3.31e-02	NA	NA
5. P	Q9RMM3	Glutamate racemase	7.49e-02	1.67e-02	NA	NA
5. P	A7ZUI7	Glutamate racemase	1.07e-01	3.78e-02	NA	NA
5. P	Q0SY24	Glutamate racemase	1.17e-01	3.31e-02	NA	NA
5. P	C5A0R6	Glutamate racemase	1.01e-01	3.25e-02	NA	NA
5. P	B5QXR2	Glutamate racemase	1.30e-01	4.89e-02	NA	NA
5. P	A8AYU3	Glutamate racemase	6.37e-02	3.15e-02	NA	NA
5. P	P40723	Glutamate racemase	1.25e-01	4.89e-02	NA	NA
5. P	Q1J8B4	Glutamate racemase	6.01e-02	4.54e-02	NA	NA
5. P	B9DTR9	Glutamate racemase	6.29e-02	3.20e-02	NA	NA
5. P	B6I5I5	Glutamate racemase	1.09e-01	3.78e-02	NA	NA
5. P	P9WP05	DegV domain-containing protein Rv2417c	0.00e+00	2.76e-54	NA	NA
5. P	A1BDJ6	Glutamate racemase	9.89e-02	4.43e-02	NA	NA
5. P	A1KVG8	Glutamate racemase	7.27e-02	1.67e-02	NA	NA
5. P	A8A775	Glutamate racemase	1.12e-01	3.78e-02	NA	NA
5. P	Q888B8	Glutamate racemase	6.36e-02	2.77e-02	NA	NA
5. P	B1XBX8	Glutamate racemase	1.04e-01	3.25e-02	NA	NA
5. P	P0A0Q9	Glutamate racemase	8.12e-02	2.32e-02	NA	NA
5. P	Q1JIG0	Glutamate racemase	6.21e-02	4.32e-02	NA	NA
5. P	Q1R3U0	Glutamate racemase	1.06e-01	3.15e-02	NA	NA
5. P	P63633	Glutamate racemase	1.05e-01	3.31e-02	NA	NA
5. P	Q8Z315	Glutamate racemase	1.14e-01	4.85e-02	NA	NA
5. P	Q7MQ40	Glutamate racemase	1.55e-01	5.03e-03	NA	NA
5. P	P22634	Glutamate racemase	1.05e-01	3.25e-02	NA	NA
5. P	Q5PK79	Glutamate racemase	1.34e-01	4.85e-02	NA	NA
5. P	Q5F6P9	Glutamate racemase	7.34e-02	3.02e-02	NA	NA
5. P	P0A0R0	Glutamate racemase	8.00e-02	2.32e-02	NA	NA
5. P	Q8KFN8	Glutamate racemase	9.50e-02	4.50e-02	NA	NA
5. P	B7LUM6	Glutamate racemase	1.09e-01	3.34e-02	NA	NA
5. P	B7MIA7	Glutamate racemase	1.12e-01	3.15e-02	NA	NA
5. P	B5BJP1	Glutamate racemase	1.13e-01	4.85e-02	NA	NA
5. P	Q8FB89	Glutamate racemase	1.05e-01	2.47e-02	NA	NA
5. P	Q8DD39	Glutamate racemase	1.42e-01	3.46e-03	NA	NA
5. P	B7NU33	Glutamate racemase	1.06e-01	2.85e-02	NA	NA
5. P	B7M723	Glutamate racemase	1.07e-01	3.78e-02	NA	NA
5. P	Q57H86	Glutamate racemase	1.14e-01	4.85e-02	NA	NA
6. F	Q8U3E3	Cell division protein FtsZ 2	3.53e-02	NA	NA	0.2394
6. F	P0A031	Cell division protein FtsZ	5.09e-02	NA	NA	0.2447
6. F	P13977	DegV domain-containing 15.5 kDa protein	2.13e-09	NA	NA	0.8304
6. F	Q9ALA3	Cell division protein FtsZ	3.40e-02	NA	NA	0.2269
6. F	Q6GHP9	Cell division protein FtsZ	5.13e-02	NA	NA	0.2404
6. F	P57308	Cell division protein FtsZ	4.30e-02	NA	NA	0.236
6. F	Q6GA26	Cell division protein FtsZ	5.12e-02	NA	NA	0.2448
6. F	Q2YXJ0	Uncharacterized protein SAB1090	2.85e-04	NA	NA	0.5417
6. F	Q8CPK4	Cell division protein FtsZ	5.31e-02	NA	NA	0.2404
6. F	Q92EU2	PTS-dependent dihydroxyacetone kinase 2, dihydroxyacetone-binding subunit DhaK	1.70e-08	NA	NA	0.5309
6. F	P0A9A7	Cell division protein FtsZ	3.94e-02	NA	NA	0.2359
6. F	Q6GHK9	Uncharacterized protein SAR1202	2.46e-07	NA	NA	0.5388
6. F	Q9CIV8	PTS-dependent dihydroxyacetone kinase, dihydroxyacetone-binding subunit DhaK	1.95e-06	NA	NA	0.4987
6. F	Q83MF6	Cell division protein FtsZ	3.10e-02	NA	NA	0.2187
6. F	Q9K9T7	Cell division protein FtsZ	5.38e-02	NA	NA	0.2461
6. F	P0A029	Cell division protein FtsZ	5.14e-02	NA	NA	0.2448
6. F	Q8NX12	Uncharacterized protein MW1109	2.43e-07	NA	NA	0.5355
6. F	Q2FHL2	Uncharacterized protein SAUSA300_1119	2.86e-04	NA	NA	0.5516
6. F	Q9ZAW3	Cell division protein FtsZ	4.22e-02	NA	NA	0.2363
6. F	Q5HPW5	Uncharacterized protein SERP0792	3.52e-04	NA	NA	0.5442
6. F	Q99UP2	Uncharacterized protein SAV1226	2.47e-07	NA	NA	0.5384
6. F	O08398	Cell division protein FtsZ	2.52e-02	NA	NA	0.2402
6. F	O34751	Uncharacterized protein YloV	6.37e-07	NA	NA	0.5744
6. F	Q927E6	PTS-dependent dihydroxyacetone kinase 1, dihydroxyacetone-binding subunit DhaK	6.56e-09	NA	NA	0.5185
6. F	Q89AQ5	Cell division protein FtsZ	3.70e-02	NA	NA	0.2219
6. F	Q83F12	Cell division protein FtsZ	8.69e-02	NA	NA	0.2231
6. F	Q5HGP5	Cell division protein FtsZ	5.13e-02	NA	NA	0.2446
6. F	Q4L5S7	Uncharacterized protein SH1689	3.20e-04	NA	NA	0.5434
6. F	P0DMR7	Cell division protein FtsZ 2	3.72e-02	NA	NA	0.2282
6. F	Q5HGK7	Uncharacterized protein SACOL1240	2.53e-07	NA	NA	0.5388
6. F	P0A9A8	Cell division protein FtsZ	3.91e-02	NA	NA	0.2376
6. F	O83405	Cell division protein FtsZ	6.27e-02	NA	NA	0.2462
6. F	A0QXE4	D-erythrulose kinase	7.79e-06	NA	NA	0.5027
6. F	P75231	Uncharacterized protein MG369 homolog	3.57e-04	NA	NA	0.5542
6. F	P47204	Cell division protein FtsZ	3.51e-02	NA	NA	0.2557
6. F	Q6G9Y7	Uncharacterized protein SAS1160	2.44e-04	NA	NA	0.532
6. F	O51929	Cell division protein FtsZ	4.37e-02	NA	NA	0.2361
6. F	Q49X07	Uncharacterized protein SSP1546	1.79e-07	NA	NA	0.5731
6. F	Q7A5Z4	Uncharacterized protein SA1069	2.51e-04	NA	NA	0.54
6. F	P45510	Dihydroxyacetone kinase	8.32e-07	NA	NA	0.5647
6. F	Q8CSV4	Uncharacterized protein SE_0901	3.46e-04	NA	NA	0.5412