Summary

The literature section presents previous knowledge about this protein. There have been five different efforts to annotate minimal organism genome. The annotations from those efforts are given in the Literature section for completeness.

AVX54885.1
JCVISYN3A_0636

Uncharacterized lipoprotein.
M. mycoides homolog: Q6MSQ9.
TIGRfam Classification: 1=Unknown.
Category: Essential.

Statistics

Total GO Annotation: 15
Unique PROST Go: 15
Unique BLAST Go: 0
Unique Foldseek Go: 0

Total Homologs: 10
Unique PROST Homologs: 10
Unique BLAST Homologs: 0
Unique Foldseek Homologs: 0

Literature

Danchin and Fang [1]: NA
Yang and Tsui [2]: Prolipoprotein lpp
Antczak et al. [3]: Lipoprotein, putative
Zhang et al. [4]: GO:0005048|signal sequence binding
Bianchi et al. [5]: "Unclear, MOPALP lipoprotein family?"

Structures and Sequence Alignment

The best structural homolog that predicted by 5. P was Q9GM44 (HEAT repeat-containing protein 1 (Fragment)) with a FATCAT P-Value: 0.039 and RMSD of 12.60 angstrom. The sequence alignment identity is 23.4%.
Structural alignment shown in left. Query protein AVX54885.1 colored as red in alignment, homolog Q9GM44 colored as blue. Query protein AVX54885.1 is also shown in right top, homolog Q9GM44 showed in right bottom. They are colored based on secondary structures. 

  AVX54885.1 --------------------MKKILAIL---SSL----TLVSTGVFSTVLS-CKKTLTPTTKPNTNNN-KVLKNNSLDNIKTISAML-LKQAVLADMYGY 70
      Q9GM44 QKKSQDLESVQEVGGSYWQRVTLILELLQHKKKLKSPQILVPT-LFN-LLSRC---LEPL--PQEQGNMEYTKQ--L--I--LSCLLNICQKLSPD--GG 85

  AVX54885.1 NF--DFL---KSYFNNKNLNEQAKRYKLNTEIKDN-----ITLST---DFED-ALANYFS--TNLVIKKNDNV-NLDGIKGTD-IDFLTSVLPKTVFGTT 152
      Q9GM44 KIPKDVLDEEK--F-NVELIVQCVR--L-SEMAQTHHHALLLLGTVAGIFPDKVLHNIMSIFTFM----GANVMRLD-----DTYSF--QVINKTV---- 164

  AVX54885.1 SKQISAAISIILENISGAGITGLLDLAKNID-----VNSKFSDFVKNLNVSKEL--ITTLLNTIFTNDKFLKEL-----EEEINK------F---DALTL 231
      Q9GM44 -KMV---IPALIQSDSGDSI----EVSRNVEEIVVKIISVFVDALPHVPEHRRLPILVQLVDTL-GAEKFLWVLLILLFEQYVTKTVLAAAYGEKDAI-L 254

  AVX54885.1 YKD----FEL-SELS---NL-ALLNILDGINGIL----DKDYQLVSSDIKKNNGSTLN--VKLWN----TSKTFINKVAKFDQTSNVSTISSFSNSTSPT 312
      Q9GM44 EADTEFWFSVCCEFSVQHQIQSLMNIL---QYLLKLPEEKE-ETISKAV-SNKSESQEEMLQIFNVETHTSKQL--RHFKF-----LS-VSFMSQ----- 336

  AVX54885.1 ILPTN--IKRNIKTAA-SLIRGLE--LFQ----YLFSLFD--ESRKD----EF------KISDENIFDKSKKN----SE-FIKNIYKINGSTGGSN---N 383
      Q9GM44 LLSSNNFLKKVVESGGPEILKGLEERLLETVLGYINAVAQSMERNADKLTVKFWRALLSKAYD--LLD--KVNALLPTETFIP-V--IRGLVG--NRLPS 427

  AVX54885.1 GSNK-IESLNG--TSNGSTSKT--TLNLKYIIDTLQYYLGNLDKSDKAYRLRQFIAILFSGKYTENIY--KPENNNNG--NG-------SNEYKSFFFEF 467
      Q9GM44 VRRKALDLLNNKLQQNISWKKTIVTRFLKLVPD-L---LAIVQRKKKEGEEEQ--AI---NRQTA-LYTLKLLCKNFGAENPDPFVPVLSTAVKLI---- 513

  AVX54885.1 NGAPENKIKEIKLN--GFQIF----LTSILFESLSNIKLQNIKIESGIFSLAKPFIEKI-NLKNFFE---SEVFLKKGLADFLISLMNLI-T-DSFVYNQ 555
      Q9GM44 --APER--KEEK-NVLGSALLCVAEVTSTL-QALA---VPQLP------SLM-PSL--LTTMKNTSELVSSEVYL---L-SALAALQKVVETLPHFI--S 589

  AVX54885.1 PLVNDNFDKILENLVTILK-TLKFDDLLKALFNETNGI-VSSLKSLIEKYVKFEDISKKIDEFIKKKETF-SLVK-----VGIKSFIPILGEKFFEYIYD 647
      Q9GM44 PYL----EGILSQVIHLEKIT---SEVGSA-SSQAN-IRLTSLKKTLATTL----APRVLLPAIRK--TYKQIEKNWKNHMG--PFMSILQ----EHI-- 666

  AVX54885.1 G---KVEQT--------F-----DTLANLS-NDV--LIRTLVEKLKIQIPAALNFILPYFKKIAMSLR----TIFPPNVHLNLKNLFTIKLSDFIKLENK 724
      Q9GM44 GVMKKEELTSHQSQLTAFFLEALDFRAQHSENDLEEVGRT--E----------NCIIDCL--VAMVVKLSEVT-FRP--------LF-FKLFDWAKTEDA 742

  AVX54885.1 PNFGSDYLDKSITTILNELSGADGSGSKLKDLDNAY-G--FK--IDSLKEFINKIFKYDYKWNGKDLENGN-----LISLLLNNPNKFKEIIGL--TEEG 812
      Q9GM44 PK------DR-LLTFYN-L--ADCIAEKLKGLFTLFAGHLVKPFADTLNQ-VN-ISKTDEAF--FDSENDPEKCCLLLQFILN--CLYK--IFLFDTQHF 824

  AVX54885.1 MKKDSK-----SLIDILSNKLIPNDK-----SKK-------------QDSLQWFAGVLNKVIINLNKKP-NFTISLEKHFNNDKFNNFEFSETKAEKSGL 888
      Q9GM44 ISKERAEALMMPLVDQLENRLGGEEKFQERVTKQLIPCIAQFSVAMADDSL-W--------------KPLNYQI-LLK--TRD-------ASPKVRFAAL 899

  AVX54885.1 ITSQTISTTINNQKYTLVITRDPKQSTFIVESLTKQLVQNN--------------------------- 929
      Q9GM44 ITVLALAEKL-KENYIVLL---PESIPFLAE-----LMEDECEEVEHQCQKTIQQLETVLGEPLRSYF 958

Go Annotations

1. PBF indicates the go terms that are found by both PROST and BLAST and Foldseek.
2. PF indicates the go terms that are found by only PROST and Foldseek.
3. BF indicates the go terms that are found by only BLAST and Foldseek.
4. PB indicates the go terms that are found by both PROST and BLAST.
5. P indicates the go terms that are found by only PROST.
6. F indicates the go terms that are found by only Foldseek.
7. B indicates the go terms that are found by only BLAST.

Source GO Description
5. P GO:0042025 host cell nucleus
5. P GO:0006351 transcription, DNA-templated
5. P GO:0033650 host cell mitochondrion
5. P GO:0003968 RNA-directed 5'-3' RNA polymerase activity
5. P GO:0075526 cap snatching
5. P GO:0039616 T=2 icosahedral viral capsid
5. P GO:0003723 RNA binding
5. P GO:0075521 microtubule-dependent intracellular transport of viral material towards nucleus
5. P GO:0039623 T=25 icosahedral viral capsid
5. P GO:0006370 7-methylguanosine mRNA capping
5. P GO:0039625 viral inner capsid
5. P GO:0019013 viral nucleocapsid
5. P GO:0039694 viral RNA genome replication
5. P GO:0039523 suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity
5. P GO:0039545 suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity

Uniprot GO Annotations

GO Description

Homologs

1. PBF indicates the homologs that are found by both PROST and BLAST and Foldseek.
2. PF indicates the homologs that are found by only PROST and Foldseek.
3. BF indicates the homologs that are found by only BLAST and Foldseek.
4. PB indicates the homologs that are found by both PROST and BLAST.
5. P indicates the homologs that are found by only PROST.
6. F indicates the homologs that are found by only Foldseek.
7. B indicates the homologs that are found by only BLAST.

Source Homolog Description Fatcat Pvalue PROST Evalue BLAST Evalue Foldseek TMScore
5. P Q9GM44 HEAT repeat-containing protein 1 (Fragment) 3.90e-02 4.76e-02 NA NA
5. P A4GCK7 Polymerase basic protein 2 NA 1.91e-02 NA NA
5. P O36431 Polymerase basic protein 2 NA 6.34e-03 NA NA
5. P Q86108 Inner capsid protein VP2 NA 5.49e-03 NA NA
5. P A3DRQ0 Polymerase basic protein 2 NA 3.93e-02 NA NA
5. P P13875 Polymerase basic protein 2 NA 6.04e-03 NA NA
5. P Q1WNZ9 Polymerase basic protein 2 NA 4.34e-02 NA NA
5. P P03278 Hexon protein NA 1.54e-02 NA NA
5. P Q9QLL6 Polymerase basic protein 2 NA 1.12e-02 NA NA
5. P P13876 Polymerase basic protein 2 NA 4.22e-03 NA NA