Results | PROST

Summary

The literature section presents previous knowledge about this protein. There have been five different efforts to annotate minimal organism genome. The annotations from those efforts are given in the Literature section for completeness.

AVX54930.1

JCVISYN3A_0692

Uncharacterized pseudouridine synthase.
M. mycoides homolog: Q6MSK6.
TIGRfam Classification: 2=Generic.
Category: Nonessential.

Statistics

Total GO Annotation: 24
Unique PROST Go: 0
Unique BLAST Go: 4
Unique Foldseek Go: 0

Total Homologs: 202
Unique PROST Homologs: 30
Unique BLAST Homologs: 8
Unique Foldseek Homologs: 13

Literature

Danchin and Fang [1]: promiscuous 23S ribosomal RNA pseudouridylate synthase|important for termination of translation
Yang and Tsui [2]: RNA pseudouridylate synthase RluC
Antczak et al. [3]: Ribosomal large subunit pseudouridine synthase Rlu family
Zhang et al. [4]: GO:0000455|enzyme-directed rRNA pseudouridine synthesis
Bianchi et al. [5]: rluC-like pseudouridine synthase RNA binding

Structures and Sequence Alignment

The best structural homolog that predicted by 1. PBF was Q8FIP7 (Ribosomal large subunit pseudouridine synthase C) with a FATCAT P-Value: 0 and RMSD of 3.01 angstrom. The sequence alignment identity is 26.8%.
Structural alignment shown in left. Query protein AVX54930.1 colored as red in alignment, homolog Q8FIP7 colored as blue. Query protein AVX54930.1 is also shown in right top, homolog Q8FIP7 showed in right bottom. They are colored based on secondary structures.

  AVX54930.1 M-T-----KFV-VNKNDQNQTLFKFLKKTFKTTPISVIYKWIRNKSIKINSKRISDK-NYLLKINDVIEVYDSNKPI-I--RDQ--FN-YISNV-NL-D- 83
      Q8FIP7 MKTETPSVKIVAITADEAGQRIDNFLRTQLKGVPKSMIYRILRKGEVRVNKKRI--KPEYKLEAGDEVRI----PPVRVAEREEEAVSPHLQKVAALADV 94

  AVX54930.1 IVYEDNNILIVNKPNNLEMHSTYNLC--LDDMVKSYLVDKKEYDIYLENSFVISHVHRLDKLTSGLVIYAKNKISSTI--LTNAFKSKDQINKYYYALTS 179
      Q8FIP7 ILYEDDHILVLNKPSGTAVHGGSGLSFGVIEGLRA-L--RPE-ARFLE---L---VHRLDRDTSGVLLVAK-K-RSALRSLHEQLREKG-MQKDYLALVR 181

  AVX54930.1 SDW-----SLDEFLQVNGYINYDSNIKKADFSLDKKNNYKYCQTEFKLINKNLI--LVKL--ITGKKHQIRSVLSFY-NHPILNDFRYNG-----KKIND 264
      Q8FIP7 GQWQSYVKSVQAPL-LKNILQSGERIVR--VSQEGKPS----ETRFKVEERYAFATLVRCSPVTGRTHQIR-VHTQYAGHPIAFDDRY-GDREFDRQLTE 272

  AVX54930.1 ----LKMIYLSAFKIEFKN--------LEKPLDY-LN---NKVFIKNPEWISKE 302
      Q8FIP7 AGTGLNRLFLHAAALKFTHPGTGEVMRIEAPMDEGLKRCLQK--LRNAR----- 319

Go Annotations

1. PBF indicates the go terms that are found by both PROST and BLAST and Foldseek.
2. PF indicates the go terms that are found by only PROST and Foldseek.
3. BF indicates the go terms that are found by only BLAST and Foldseek.
4. PB indicates the go terms that are found by both PROST and BLAST.
5. P indicates the go terms that are found by only PROST.
6. F indicates the go terms that are found by only Foldseek.
7. B indicates the go terms that are found by only BLAST.

Source	GO	Description
1. PBF	GO:0070131	positive regulation of mitochondrial translation
1. PBF	GO:0008033	tRNA processing
1. PBF	GO:0000455	enzyme-directed rRNA pseudouridine synthesis
1. PBF	GO:0003723	RNA binding
1. PBF	GO:0001522	pseudouridine synthesis
1. PBF	GO:0009982	pseudouridine synthase activity
1. PBF	GO:0000154	rRNA modification
1. PBF	GO:0009451	RNA modification
1. PBF	GO:0006364	rRNA processing
1. PBF	GO:0106029	tRNA pseudouridine synthase activity
1. PBF	GO:0120159	rRNA pseudouridine synthase activity
1. PBF	GO:0005759	mitochondrial matrix
3. BF	GO:0004730	pseudouridylate synthase activity
4. PB	GO:0031119	tRNA pseudouridine synthesis
4. PB	GO:0035770	ribonucleoprotein granule
4. PB	GO:0031118	rRNA pseudouridine synthesis
4. PB	GO:1990400	mitochondrial ribosomal large subunit rRNA binding
4. PB	GO:0005739	mitochondrion
4. PB	GO:0005737	cytoplasm
4. PB	GO:0070902	mitochondrial tRNA pseudouridine synthesis
7. B	GO:0006399	tRNA metabolic process
7. B	GO:1990481	mRNA pseudouridine synthesis
7. B	GO:0043723	2,5-diamino-6-ribitylamino-4(3H)-pyrimidinone 5'-phosphate deaminase activity
7. B	GO:0008835	diaminohydroxyphosphoribosylaminopyrimidine deaminase activity

Uniprot GO Annotations

GO	Description
GO:0004730	pseudouridylate synthase activity
GO:0000455	enzyme-directed rRNA pseudouridine synthesis
GO:0003723	RNA binding
GO:0016829	lyase activity
GO:0001522	pseudouridine synthesis
GO:0009982	pseudouridine synthase activity
GO:0009451	RNA modification
GO:0120159	rRNA pseudouridine synthase activity

Homologs

1. PBF indicates the homologs that are found by both PROST and BLAST and Foldseek.
2. PF indicates the homologs that are found by only PROST and Foldseek.
3. BF indicates the homologs that are found by only BLAST and Foldseek.
4. PB indicates the homologs that are found by both PROST and BLAST.
5. P indicates the homologs that are found by only PROST.
6. F indicates the homologs that are found by only Foldseek.
7. B indicates the homologs that are found by only BLAST.

Source	Homolog	Description	Fatcat Pvalue	PROST Evalue	BLAST Evalue	Foldseek TMScore
1. PBF	P57430	Ribosomal large subunit pseudouridine synthase C	2.34e-13	5.73e-28	5.96e-24	0.6635
1. PBF	P44445	Ribosomal large subunit pseudouridine synthase D	2.07e-14	2.62e-26	6.70e-14	0.6055
1. PBF	Q9PET9	Ribosomal large subunit pseudouridine synthase D	1.09e-12	1.35e-28	6.77e-16	0.6073
1. PBF	Q8DEV0	Ribosomal large subunit pseudouridine synthase D	3.05e-14	4.22e-26	5.43e-16	0.6193
1. PBF	Q8P682	Ribosomal large subunit pseudouridine synthase D	5.00e-14	2.01e-26	2.98e-12	0.6341
1. PBF	Q9JVB6	Ribosomal large subunit pseudouridine synthase D	2.99e-13	2.77e-13	1.63e-12	0.6141
1. PBF	P65834	Ribosomal large subunit pseudouridine synthase D	1.16e-13	4.21e-28	2.83e-16	0.5824
1. PBF	Q8K9E9	Ribosomal large subunit pseudouridine synthase D	7.33e-14	4.93e-37	5.25e-13	0.6019
1. PBF	O25610	Uncharacterized RNA pseudouridine synthase HP_0956	4.37e-09	1.09e-34	1.01e-08	0.6293
1. PBF	P75230	Uncharacterized RNA pseudouridine synthase MG370 homolog	0.00e+00	2.88e-42	5.39e-11	0.8176
1. PBF	P0AA38	Dual-specificity RNA pseudouridine synthase RluA	8.33e-14	1.15e-06	6.05e-11	0.7901
1. PBF	Q8Z7J7	Ribosomal large subunit pseudouridine synthase C	0.00e+00	1.08e-30	2.50e-22	0.68
1. PBF	O25441	Uncharacterized RNA pseudouridine synthase HP_0745	5.76e-13	7.63e-36	8.18e-20	0.6467
1. PBF	Q89AD9	Ribosomal large subunit pseudouridine synthase D	2.62e-14	1.69e-32	1.69e-09	0.5735
1. PBF	P47610	Uncharacterized RNA pseudouridine synthase MG370	0.00e+00	1.95e-44	1.21e-11	0.7349
1. PBF	P0AA40	Ribosomal large subunit pseudouridine synthase C	0.00e+00	9.85e-31	9.65e-22	0.7177
1. PBF	Q8XYX8	Ribosomal large subunit pseudouridine synthase D	1.51e-13	8.20e-25	1.23e-17	0.558
1. PBF	P65837	Ribosomal large subunit pseudouridine synthase D	3.94e-14	3.31e-27	1.27e-15	0.5817
1. PBF	P44433	Ribosomal large subunit pseudouridine synthase C	1.12e-13	4.60e-35	3.46e-22	0.6543
1. PBF	Q82WZ5	Ribosomal large subunit pseudouridine synthase D	1.92e-13	5.92e-23	8.51e-11	0.6147
1. PBF	O25114	Uncharacterized RNA pseudouridine synthase HP_0347	7.21e-13	8.62e-31	0.002	0.5612
1. PBF	Q8X8J3	Ribosomal large subunit pseudouridine synthase C	2.98e-13	4.52e-31	1.11e-21	0.663
1. PBF	Q8Z9J5	Dual-specificity RNA pseudouridine synthase RluA	8.59e-14	1.32e-07	1.61e-11	0.7907
1. PBF	Q9K0B0	Ribosomal large subunit pseudouridine synthase D	4.05e-13	7.95e-13	4.09e-13	0.6169
1. PBF	Q92IS6	Ribosomal large subunit pseudouridine synthase C	2.97e-13	3.57e-43	1.93e-16	0.6771
1. PBF	Q87AR7	Ribosomal large subunit pseudouridine synthase D	1.62e-12	4.62e-32	2.67e-16	0.5812
1. PBF	Q1RJX7	Ribosomal large subunit pseudouridine synthase C	2.80e-13	1.35e-41	3.55e-18	0.7162
1. PBF	Q9KU20	Ribosomal large subunit pseudouridine synthase D	3.15e-14	3.83e-25	2.26e-14	0.588
1. PBF	P47451	Uncharacterized RNA pseudouridine synthase MG209	8.66e-15	2.18e-40	2.79e-19	0.6008
1. PBF	P50513	Ribosomal large subunit pseudouridine synthase D	2.15e-13	3.69e-35	1.86e-15	0.6704
1. PBF	Q9KQH0	Ribosomal large subunit pseudouridine synthase C	3.18e-14	5.56e-33	4.23e-25	0.6712
1. PBF	P33640	Ribosomal large subunit pseudouridine synthase D	4.54e-13	9.65e-35	4.20e-12	0.6072
1. PBF	Q8D8G1	Ribosomal large subunit pseudouridine synthase C	1.11e-16	3.23e-30	7.65e-24	0.6705
1. PBF	Q9CKA6	Ribosomal large subunit pseudouridine synthase D	6.11e-14	1.97e-26	1.00e-11	0.6258
1. PBF	Q8FL93	Dual-specificity RNA pseudouridine synthase RluA	7.84e-14	1.81e-06	9.83e-11	0.7888
1. PBF	P59831	Dual-specificity RNA pseudouridine synthase RluA	8.38e-14	2.81e-08	1.32e-07	0.7687
1. PBF	Q8ZQ16	Ribosomal large subunit pseudouridine synthase C	0.00e+00	1.77e-29	1.67e-22	0.6837
1. PBF	Q8FIP7	Ribosomal large subunit pseudouridine synthase C	0.00e+00	4.52e-31	1.25e-21	0.7157
1. PBF	P54604	Uncharacterized RNA pseudouridine synthase YhcT	2.22e-16	3.99e-43	1.52e-20	0.6309
1. PBF	Q45480	Uncharacterized RNA pseudouridine synthase YlyB	7.33e-14	1.11e-44	3.47e-18	0.6489
1. PBF	Q89AH2	Ribosomal large subunit pseudouridine synthase C	2.45e-13	1.06e-27	3.39e-22	0.6419
1. PBF	Q9ZL98	Uncharacterized RNA pseudouridine synthase jhp_0682	1.04e-12	1.66e-36	9.98e-20	0.6337
1. PBF	P65835	Ribosomal large subunit pseudouridine synthase D	4.21e-14	4.21e-28	2.83e-16	0.5829
1. PBF	Q9HZM9	Ribosomal large subunit pseudouridine synthase C	5.55e-14	1.83e-37	7.55e-23	0.6255
1. PBF	Q87S65	Ribosomal large subunit pseudouridine synthase D	3.03e-14	1.81e-25	5.76e-15	0.5725
1. PBF	Q8ZRV9	Dual-specificity RNA pseudouridine synthase RluA	7.98e-14	6.25e-08	1.43e-11	0.7911
1. PBF	P45614	Uncharacterized RNA pseudouridine synthase MCAP_0714	0.00e+00	1.97e-84	0.0	0.9924
1. PBF	P59835	Ribosomal large subunit pseudouridine synthase C	1.27e-13	4.31e-33	1.04e-23	0.6717
1. PBF	P59838	Ribosomal large subunit pseudouridine synthase D	1.59e-14	3.77e-37	2.57e-13	0.6158
1. PBF	O50310	Uncharacterized RNA pseudouridine synthase Cpar_0723	5.93e-11	2.39e-29	2.00e-11	0.6258
1. PBF	Q4UKQ3	Ribosomal large subunit pseudouridine synthase C	6.49e-14	6.93e-44	1.51e-16	0.7074
1. PBF	Q9CK02	Dual-specificity RNA pseudouridine synthase RluA	8.65e-14	7.64e-08	2.75e-08	0.7678
1. PBF	Q47417	tRNA pseudouridine synthase C	1.04e-06	2.59e-19	8.80e-11	0.5873
1. PBF	Q8ZFU1	Ribosomal large subunit pseudouridine synthase C	4.91e-14	7.44e-37	4.51e-16	0.6883
1. PBF	Q68XB2	Ribosomal large subunit pseudouridine synthase C	1.57e-13	3.10e-47	3.09e-17	0.6945
1. PBF	Q5E9Z1	Mitochondrial RNA pseudouridine synthase RPUSD4	9.89e-09	1.68e-10	1.74e-07	0.6427
1. PBF	Q87N15	Ribosomal large subunit pseudouridine synthase C	0.00e+00	3.90e-30	5.32e-23	0.7179
1. PBF	Q9L7A7	Ribosomal large subunit pseudouridine synthase D	3.82e-13	9.31e-26	1.42e-13	0.6105
1. PBF	Q8K9J8	Ribosomal large subunit pseudouridine synthase C	3.74e-13	4.40e-33	5.49e-20	0.6444
1. PBF	Q9ZMA1	Uncharacterized RNA pseudouridine synthase jhp_0321	7.43e-13	2.32e-34	0.002	0.5996
1. PBF	P0A5T3	Uncharacterized RNA pseudouridine synthase Mb1567	3.65e-12	7.92e-32	2.47e-10	0.5979
1. PBF	P65836	Ribosomal large subunit pseudouridine synthase D	4.13e-14	3.31e-27	1.27e-15	0.583
1. PBF	Q8X9F0	Ribosomal large subunit pseudouridine synthase D	4.29e-14	2.14e-28	4.09e-16	0.5821
1. PBF	P74346	Uncharacterized RNA pseudouridine synthase slr1629	2.82e-13	4.03e-31	5.73e-11	0.677
1. PBF	Q8XA10	Dual-specificity RNA pseudouridine synthase RluA	7.74e-14	4.33e-07	4.98e-10	0.7888
1. PBF	P57481	Ribosomal large subunit pseudouridine synthase D	9.15e-14	2.02e-30	2.67e-09	0.6077
1. PBF	Q8PHN2	Ribosomal large subunit pseudouridine synthase D	1.60e-13	9.02e-28	1.59e-11	0.6234
1. PBF	O67638	Uncharacterized RNA pseudouridine synthase aq_1758	1.59e-13	1.10e-36	2.35e-13	0.6408
1. PBF	P9WHQ2	Uncharacterized RNA pseudouridine synthase MT1592	3.58e-12	7.92e-32	2.47e-10	0.5959
1. PBF	Q9ZDR7	Ribosomal large subunit pseudouridine synthase C	2.10e-13	6.03e-48	3.31e-19	0.6915
1. PBF	Q28C59	Mitochondrial RNA pseudouridine synthase rpusd4	1.89e-07	2.73e-05	3.45e-08	0.6337
1. PBF	O31613	Uncharacterized RNA pseudouridine synthase YjbO	1.42e-13	1.34e-35	1.60e-11	0.646
1. PBF	Q9ZKP5	Uncharacterized RNA pseudouridine synthase jhp_0890	4.16e-09	3.31e-36	7.78e-08	0.5723
1. PBF	O66114	Uncharacterized RNA pseudouridine synthase ZMO0505	7.88e-15	1.66e-02	1.09e-09	0.7735
1. PBF	P75485	Uncharacterized RNA pseudouridine synthase MG209 homolog	2.33e-15	8.71e-33	4.75e-18	0.5813
1. PBF	P44782	Dual-specificity RNA pseudouridine synthase RluA	5.57e-14	5.06e-06	4.40e-10	0.8077
1. PBF	P72970	Uncharacterized RNA pseudouridine synthase slr1592	1.81e-11	1.77e-26	2.98e-07	0.5937
1. PBF	Q8ZBV7	Ribosomal large subunit pseudouridine synthase D	8.79e-14	1.79e-27	1.27e-18	0.6219
1. PBF	Q9CM51	Ribosomal large subunit pseudouridine synthase C	6.98e-14	1.10e-31	7.34e-22	0.6814
1. PBF	P70870	Ribosomal large subunit pseudouridine synthase D	9.37e-11	2.83e-34	1.44e-16	0.6065
1. PBF	Q45826	Uncharacterized RNA pseudouridine synthase Caur_0901	1.74e-13	3.76e-30	2.64e-14	0.6643
2. PF	O66829	Uncharacterized RNA pseudouridine synthase aq_554	6.25e-07	5.49e-07	NA	0.5822
2. PF	Q9CPN4	Ribosomal small subunit pseudouridine synthase A	7.15e-07	5.22e-12	NA	0.4679
2. PF	Q8ZGM2	Ribosomal small subunit pseudouridine synthase A	7.22e-07	1.29e-10	NA	0.4634
2. PF	P65843	Uncharacterized RNA pseudouridine synthase Mb1738	2.25e-06	1.40e-12	NA	0.409
2. PF	Q87QD4	Ribosomal small subunit pseudouridine synthase A	9.36e-07	1.98e-13	NA	0.4583
2. PF	Q8FHV4	Ribosomal large subunit pseudouridine synthase B	8.43e-06	1.00e-03	NA	0.4221
2. PF	P45124	Ribosomal small subunit pseudouridine synthase A	6.86e-07	1.67e-14	NA	0.4836
2. PF	Q8X4Q8	Ribosomal large subunit pseudouridine synthase B	8.41e-06	9.68e-04	NA	0.44
2. PF	P0AA45	Ribosomal small subunit pseudouridine synthase A	6.44e-07	1.16e-10	NA	0.4694
2. PF	Q2TBK7	Mitochondrial mRNA pseudouridine synthase RPUSD3	7.21e-08	2.27e-09	NA	0.7042
2. PF	O67444	Uncharacterized RNA pseudouridine synthase aq_1464	1.28e-06	2.63e-07	NA	0.4705
2. PF	P9WHQ0	Uncharacterized RNA pseudouridine synthase MT1751.1	2.24e-05	1.40e-12	NA	0.4902
2. PF	Q68WJ1	Uncharacterized RNA pseudouridine synthase RT0532	1.70e-06	2.05e-05	NA	0.4864
2. PF	P35159	Ribosomal large subunit pseudouridine synthase B	1.44e-06	4.93e-07	NA	0.4655
2. PF	O05668	Uncharacterized RNA pseudouridine synthase ML1370	2.20e-05	7.69e-12	NA	0.4996
2. PF	Q92HG4	Uncharacterized RNA pseudouridine synthase RC0807	4.21e-07	2.13e-04	NA	0.5069
2. PF	P59815	Ribosomal large subunit pseudouridine synthase B	8.21e-06	1.35e-03	NA	0.4277
2. PF	Q8Z7D5	Ribosomal large subunit pseudouridine synthase B	8.69e-06	1.32e-03	NA	0.4273
2. PF	Q9KRK5	Ribosomal small subunit pseudouridine synthase A	3.50e-07	3.02e-10	NA	0.4816
2. PF	P0AA44	Ribosomal small subunit pseudouridine synthase A	6.71e-07	1.16e-10	NA	0.4694
2. PF	Q9I5J6	Ribosomal small subunit pseudouridine synthase A	1.67e-07	1.19e-11	NA	0.5034
2. PF	Q1RJR2	Uncharacterized RNA pseudouridine synthase RBE_0321	9.34e-07	5.66e-05	NA	0.5056
2. PF	P0AA46	Ribosomal small subunit pseudouridine synthase A	6.42e-07	1.16e-10	NA	0.474
2. PF	P57369	Ribosomal large subunit pseudouridine synthase B	5.57e-06	3.11e-05	NA	0.4438
2. PF	Q55578	Uncharacterized RNA pseudouridine synthase slr0361	5.66e-06	9.24e-09	NA	0.447
2. PF	Q9ZD06	Uncharacterized RNA pseudouridine synthase RP544	6.78e-07	4.70e-05	NA	0.5027
2. PF	P42395	Ribosomal large subunit pseudouridine synthase B	7.06e-06	2.42e-08	NA	0.4476
2. PF	Q4UL59	Uncharacterized RNA pseudouridine synthase RF_0863	8.35e-07	1.13e-04	NA	0.4868
2. PF	Q8ZP51	Ribosomal large subunit pseudouridine synthase B	8.43e-06	1.33e-03	NA	0.4473
2. PF	Q8D8X2	Ribosomal small subunit pseudouridine synthase A	7.76e-07	9.56e-12	NA	0.4804
2. PF	P65841	Ribosomal small subunit pseudouridine synthase A	8.68e-07	8.30e-12	NA	0.4743
2. PF	P65840	Ribosomal small subunit pseudouridine synthase A	5.13e-07	8.30e-12	NA	0.4787
3. BF	Q6FS81	21S rRNA pseudouridine(2819) synthase	2.26e-14	NA	5.76e-05	0.7162
3. BF	Q9KTL4	tRNA pseudouridine synthase C	7.63e-14	NA	5.29e-09	0.6645
3. BF	Q8ZMD5	tRNA pseudouridine synthase C	2.99e-13	NA	3.32e-08	0.6293
3. BF	Q9KP71	Dual-specificity RNA pseudouridine synthase RluA	2.41e-13	NA	1.07e-09	0.6787
3. BF	Q750S3	21S rRNA pseudouridine(2819) synthase	1.30e-13	NA	2.08e-06	0.6482
3. BF	Q87MD4	tRNA pseudouridine synthase C	2.58e-13	NA	5.12e-11	0.6848
3. BF	Q8DBG5	tRNA pseudouridine synthase C	1.67e-13	NA	9.10e-11	0.661
3. BF	P0AA42	tRNA pseudouridine synthase C	3.20e-13	NA	9.27e-10	0.6394
3. BF	Q8X6T6	tRNA pseudouridine synthase C	3.06e-13	NA	7.52e-10	0.6307
3. BF	P43930	Uncharacterized RNA pseudouridine synthase HI_0042	7.77e-16	NA	1.43e-14	0.7763
3. BF	Q8ZH72	tRNA pseudouridine synthase C	1.65e-13	NA	8.70e-09	0.6676
3. BF	Q8ZIK1	Dual-specificity RNA pseudouridine synthase RluA	0.00e+00	NA	1.21e-09	0.825
3. BF	Q8Z439	tRNA pseudouridine synthase C	2.36e-13	NA	4.48e-08	0.6319
3. BF	Q8FEF9	tRNA pseudouridine synthase C	3.41e-13	NA	7.74e-10	0.6311
3. BF	Q87LD3	Dual-specificity RNA pseudouridine synthase RluA	2.22e-16	NA	1.12e-10	0.6304
3. BF	Q6CQC4	21S rRNA pseudouridine(2819) synthase	3.49e-10	NA	2.51e-06	0.6501
3. BF	P59840	tRNA pseudouridine synthase C	5.55e-12	NA	4.12e-10	0.6811
3. BF	Q9CNF3	tRNA pseudouridine synthase C	1.34e-13	NA	8.56e-11	0.6768
3. BF	Q8DCG0	Dual-specificity RNA pseudouridine synthase RluA	1.42e-13	NA	1.71e-11	0.6747
4. PB	Q9CWX4	Mitochondrial RNA pseudouridine synthase Rpusd4	2.50e-07	8.28e-11	1.14e-08	NA
4. PB	P9WHQ3	Uncharacterized RNA pseudouridine synthase Rv1540	1.89e-12	7.92e-32	2.47e-10	NA
4. PB	P0AA37	Dual-specificity RNA pseudouridine synthase RluA	7.72e-14	1.15e-06	6.05e-11	NA
4. PB	P53294	tRNA pseudouridine(31) synthase	2.25e-09	7.07e-18	8.91e-13	NA
4. PB	P0AA39	Ribosomal large subunit pseudouridine synthase C	0.00e+00	9.85e-31	9.65e-22	NA
4. PB	Q96CM3	Mitochondrial RNA pseudouridine synthase RPUSD4	3.41e-07	3.63e-11	3.69e-10	NA
4. PB	Q4QQT0	Mitochondrial RNA pseudouridine synthase Rpusd4	1.59e-05	7.40e-12	1.14e-08	NA
4. PB	P33643	Ribosomal large subunit pseudouridine synthase D	2.95e-14	4.28e-28	1.99e-16	NA
4. PB	Q12069	tRNA pseudouridine(32) synthase, mitochondrial	7.30e-11	6.81e-07	7.17e-13	NA
4. PB	Q5Z8P2	RNA pseudouridine synthase 2, chloroplastic	2.35e-11	6.05e-08	1.60e-11	NA
4. PB	Q0DST9	RNA pseudouridine synthase 5	3.07e-08	2.08e-17	8.85e-17	NA
4. PB	Q5M721	RNA pseudouridine synthase 5	3.93e-09	7.80e-22	4.25e-10	NA
4. PB	Q09709	Uncharacterized protein C18B11.02c	2.33e-10	3.69e-08	5.59e-10	NA
4. PB	Q0E0Y3	RNA pseudouridine synthase 7	1.34e-08	1.97e-10	3.71e-05	NA
4. PB	Q9LT72	RNA pseudouridine synthase 4, mitochondrial	3.61e-10	1.09e-08	1.59e-06	NA
4. PB	Q69K07	RNA pseudouridine synthase 4, mitochondrial	4.49e-09	2.05e-05	3.91e-04	NA
4. PB	Q9LU60	RNA pseudouridine synthase 7	9.11e-11	1.05e-13	8.89e-13	NA
4. PB	O16686	Uncharacterized protein K07E8.7	1.83e-11	8.92e-11	6.85e-10	NA
4. PB	Q3ECD0	RNA pseudouridine synthase 2, chloroplastic	5.75e-12	8.89e-07	3.03e-12	NA
5. P	Q0J4D4	RNA pseudouridine synthase 3, mitochondrial	9.63e-10	6.70e-11	NA	NA
5. P	Q8FIB6	Ribosomal large subunit pseudouridine synthase E	3.59e-04	9.08e-07	NA	NA
5. P	Q87QY8	Ribosomal large subunit pseudouridine synthase E	6.39e-04	9.08e-04	NA	NA
5. P	Q9CKK7	Ribosomal large subunit pseudouridine synthase E	2.60e-04	5.59e-08	NA	NA
5. P	Q8X724	Ribosomal large subunit pseudouridine synthase E	2.95e-04	6.45e-07	NA	NA
5. P	Q83LF6	Ribosomal large subunit pseudouridine synthase E	2.87e-04	5.92e-07	NA	NA
5. P	Q89AL1	Ribosomal large subunit pseudouridine synthase B	2.49e-06	1.64e-04	NA	NA
5. P	P37765	Ribosomal large subunit pseudouridine synthase B	8.06e-06	1.26e-03	NA	NA
5. P	Q2QNM3	RNA pseudouridine synthase 1	1.06e-07	3.03e-07	NA	NA
5. P	Q9SVS0	RNA pseudouridine synthase 6, chloroplastic	4.33e-06	1.37e-03	NA	NA
5. P	Q9F855	Ribosomal large subunit pseudouridine synthase E	3.85e-04	1.72e-03	NA	NA
5. P	P44827	Ribosomal large subunit pseudouridine synthase E	5.39e-04	6.38e-07	NA	NA
5. P	P9WHQ1	Uncharacterized RNA pseudouridine synthase Rv1711	2.38e-05	1.40e-12	NA	NA
5. P	P72581	Uncharacterized RNA pseudouridine synthase slr0612	NA	1.47e-03	NA	NA
5. P	P75966	Ribosomal large subunit pseudouridine synthase E	2.55e-04	4.19e-07	NA	NA
5. P	Q14AI6	Mitochondrial mRNA pseudouridine synthase Rpusd3	2.97e-08	5.41e-10	NA	NA
5. P	A3BN26	RNA pseudouridine synthase 6, chloroplastic	1.47e-06	1.62e-04	NA	NA
5. P	Q6P087	Mitochondrial mRNA pseudouridine synthase RPUSD3	5.13e-08	9.64e-10	NA	NA
5. P	Q9ZJG0	Uncharacterized RNA pseudouridine synthase jhp_1352	5.10e-06	1.71e-09	NA	NA
5. P	Q6DBR0	Mitochondrial RNA pseudouridine synthase rpusd4	2.77e-06	4.14e-13	NA	NA
5. P	Q5XET6	RNA pseudouridine synthase 3, mitochondrial	3.95e-08	2.33e-10	NA	NA
5. P	Q7XA65	RNA pseudouridine synthase 1	3.53e-10	4.25e-12	NA	NA
5. P	O32068	Uncharacterized RNA pseudouridine synthase YtzG	8.71e-07	3.32e-11	NA	NA
5. P	P55986	Uncharacterized RNA pseudouridine synthase HP_1459	2.71e-06	6.09e-09	NA	NA
5. P	P0AA43	Ribosomal small subunit pseudouridine synthase A	6.45e-07	1.16e-10	NA	NA
5. P	Q8ZFQ3	Ribosomal large subunit pseudouridine synthase E	2.32e-04	4.02e-05	NA	NA
5. P	Q8Z7G6	Ribosomal large subunit pseudouridine synthase E	5.47e-04	1.84e-08	NA	NA
5. P	Q8DAS3	Ribosomal large subunit pseudouridine synthase E	3.51e-04	4.24e-07	NA	NA
5. P	Q8ZPZ1	Ribosomal large subunit pseudouridine synthase E	4.82e-04	7.56e-08	NA	NA
5. P	O51155	Uncharacterized RNA pseudouridine synthase BB_0129	2.16e-05	5.29e-09	NA	NA
6. F	Q9CMY9	Ribosomal large subunit pseudouridine synthase B	1.91e-05	NA	NA	0.4048
6. F	Q8P8M6	Ribosomal large subunit pseudouridine synthase B	9.28e-05	NA	NA	0.4274
6. F	Q9KSS7	Ribosomal large subunit pseudouridine synthase B	8.01e-06	NA	NA	0.427
6. F	Q8ZEG0	Ribosomal large subunit pseudouridine synthase B	1.26e-05	NA	NA	0.435
6. F	P45104	Ribosomal large subunit pseudouridine synthase B	1.89e-05	NA	NA	0.3871
6. F	Q8PQN3	Ribosomal large subunit pseudouridine synthase E	6.91e-06	NA	NA	0.4493
6. F	Q87NB7	Ribosomal large subunit pseudouridine synthase B	7.06e-06	NA	NA	0.424
6. F	Q8D8C0	Ribosomal large subunit pseudouridine synthase B	8.18e-06	NA	NA	0.4387
6. F	Q87BI2	Ribosomal large subunit pseudouridine synthase B	4.46e-04	NA	NA	0.4142
6. F	Q17QT4	RNA pseudouridylate synthase domain-containing protein 1	9.54e-12	NA	NA	0.7315
6. F	Q9HZ55	Ribosomal large subunit pseudouridine synthase B	3.75e-05	NA	NA	0.3941
6. F	Q8PK58	Ribosomal large subunit pseudouridine synthase B	2.14e-04	NA	NA	0.4282
6. F	Q9PAP2	Ribosomal large subunit pseudouridine synthase B	4.52e-04	NA	NA	0.4069
7. B	Q8IZ73	RNA pseudouridylate synthase domain-containing protein 2	8.11e-09	NA	1.54e-17	NA
7. B	Q149F1	RNA pseudouridylate synthase domain-containing protein 2	4.25e-06	NA	8.52e-17	NA
7. B	Q8VCZ8	RNA pseudouridylate synthase domain-containing protein 1	9.67e-12	NA	1.85e-07	NA
7. B	Q12362	Bifunctional protein RIB2	1.59e-09	NA	1.07e-11	NA
7. B	Q08C69	RNA pseudouridylate synthase domain-containing protein 1	6.93e-12	NA	7.87e-09	NA
7. B	Q06244	21S rRNA pseudouridine(2819) synthase	1.32e-11	NA	6.57e-09	NA
7. B	P0AA41	tRNA pseudouridine synthase C	2.78e-13	NA	9.27e-10	NA
7. B	P44197	tRNA pseudouridine synthase C	NA	NA	1.23e-07	NA