Summary
The literature section presents previous knowledge about this protein. There have been five different efforts to annotate minimal organism genome. The annotations from those efforts are given in the Literature section for completeness.
AVX54954.1
JCVISYN3A_0777
Uncharacterized protein.
M. mycoides homolog: Q6MSC0.
TIGRfam Classification: 1=Unknown.
Category: Quasiessential.
Statistics
Total GO Annotation: 11
Unique PROST Go: 11
Unique BLAST Go: 0
Unique Foldseek Go: 0
Total Homologs: 48
Unique PROST Homologs: 48
Unique BLAST Homologs: 0
Unique Foldseek Homologs: 0
Structures and Sequence Alignment
The best structural homolog that predicted by 5. P was
P22403
(Protein KilB) with a FATCAT P-Value: 6.26e-05 and RMSD of 1.80 angstrom. The sequence alignment identity is 19.4%.
Structural alignment shown in left. Query protein AVX54954.1 colored as red in alignment, homolog P22403 colored as blue.
Query protein AVX54954.1 is also shown in right top, homolog P22403 showed in right bottom. They are colored based on secondary structures.
AVX54954.1 MIIFTQQTSHIPTWAVYLILVLGFF---GLIISLYGASTAFKYNKNLKNKN-NYKKV--L--NLLSTRQAYSWTQIDNIDQQGYFLIGITLKDSNYNKEK 92 P22403 MV--T--T---------LIAVIGTLAGTGL-AGLLQHRTA-RTTRDDSRRDAAVQAVAALAAALADHRRAM-WVR-E--DLR---LTGAS-PEA-YEAAR 76 AVX54954.1 --PLITLLKIT-DLKTDISRFKSNINDYKNIINYLKQYNL-TTKDLVFIIIEKVENSDELDKLLIEWNSLISA------- 161 P22403 TESHATRSAITAPLTT-VSVLAPALAPAATAAAQ-AAYDLRAAADRTAL------TTDR-DRAMAAADGLVAAAARRFGA 147
Go Annotations
1. PBF indicates the go terms that are found by both PROST and BLAST and Foldseek.
2. PF indicates the go terms that are found by only PROST and Foldseek.
3. BF indicates the go terms that are found by only BLAST and Foldseek.
4. PB indicates the go terms that are found by both PROST and BLAST.
5. P indicates the go terms that are found by only PROST.
6. F indicates the go terms that are found by only Foldseek.
7. B indicates the go terms that are found by only BLAST.
| Source | GO | Description |
|---|---|---|
| 5. P | GO:0039663 | membrane fusion involved in viral entry into host cell |
| 5. P | GO:0016021 | integral component of membrane |
| 5. P | GO:0055036 | virion membrane |
| 5. P | GO:0019064 | fusion of virus membrane with host plasma membrane |
| 5. P | GO:0031207 | Sec62/Sec63 complex |
| 5. P | GO:0009401 | phosphoenolpyruvate-dependent sugar phosphotransferase system |
| 5. P | GO:0019031 | viral envelope |
| 5. P | GO:0031204 | posttranslational protein targeting to membrane, translocation |
| 5. P | GO:0039693 | viral DNA genome replication |
| 5. P | GO:0006909 | phagocytosis |
| 5. P | GO:0033644 | host cell membrane |
Uniprot GO Annotations
| GO | Description |
|---|---|
| GO:0016020 | membrane |
| GO:0016021 | integral component of membrane |
Homologs
1. PBF indicates the homologs that are found by both PROST and BLAST and Foldseek.
2. PF indicates the homologs that are found by only PROST and Foldseek.
3. BF indicates the homologs that are found by only BLAST and Foldseek.
4. PB indicates the homologs that are found by both PROST and BLAST.
5. P indicates the homologs that are found by only PROST.
6. F indicates the homologs that are found by only Foldseek.
7. B indicates the homologs that are found by only BLAST.
| Source | Homolog | Description | Fatcat Pvalue | PROST Evalue | BLAST Evalue | Foldseek TMScore |
|---|---|---|---|---|---|---|
| 5. P | P0CA80 | Membrane protein I177L | NA | 4.32e-02 | NA | NA |
| 5. P | P68711 | Virion membrane protein A21 | NA | 3.95e-05 | NA | NA |
| 5. P | P42539 | Uncharacterized 18.2 kDa protein | NA | 2.60e-02 | NA | NA |
| 5. P | P53432 | Uncharacterized protein ML1147 | 4.26e-02 | 7.87e-08 | NA | NA |
| 5. P | P15081 | Glucitol operon activator protein | 4.25e-03 | 2.45e-03 | NA | NA |
| 5. P | Q9UUA4 | Translocation protein sec66 | 6.57e-02 | 1.36e-02 | NA | NA |
| 5. P | P44043 | Uncharacterized protein HI_0725 | 1.27e-03 | 1.16e-07 | NA | NA |
| 5. P | D6VPM8 | Putative DUP240 protein YAR023C | 2.91e-02 | 2.26e-05 | NA | NA |
| 5. P | O14068 | UPF0357 protein C1687.07 | 7.61e-02 | 9.94e-03 | NA | NA |
| 5. P | Q58423 | Uncharacterized protein MJ1017 | 3.49e-02 | 2.56e-02 | NA | NA |
| 5. P | P0ADL4 | Uncharacterized protein YicN | 1.52e-02 | 8.43e-06 | NA | NA |
| 5. P | P0CA52 | Uncharacterized protein E146L | NA | 6.14e-03 | NA | NA |
| 5. P | O29709 | Uncharacterized protein AF_0541 | 6.24e-03 | 1.42e-05 | NA | NA |
| 5. P | Q91FJ9 | Uncharacterized protein 325L | NA | 1.40e-03 | NA | NA |
| 5. P | P0DSR7 | Virion membrane protein A21 | NA | 3.27e-04 | NA | NA |
| 5. P | P94520 | Sigma-w pathway protein YsdB | 3.05e-02 | 2.83e-11 | NA | NA |
| 5. P | P0CA61 | Uncharacterized protein EP152R | NA | 4.06e-04 | NA | NA |
| 5. P | O67017 | Uncharacterized protein aq_850 | 4.52e-03 | 2.13e-02 | NA | NA |
| 5. P | P0DOM3 | Protein G3 | NA | 1.81e-02 | NA | NA |
| 5. P | O83185 | Uncharacterized protein TP_0150 | 2.36e-03 | 1.45e-06 | NA | NA |
| 5. P | Q9DHJ5 | Envelope protein A28 homolog | NA | 7.81e-05 | NA | NA |
| 5. P | P0ADL3 | Uncharacterized protein YicN | 1.53e-02 | 8.43e-06 | NA | NA |
| 5. P | Q65240 | Uncharacterized protein E146L | NA | 1.36e-02 | NA | NA |
| 5. P | P45711 | Membrane protein YneK | 5.53e-03 | 1.47e-04 | NA | NA |
| 5. P | P9WM28 | Uncharacterized protein MT1352 | 4.84e-02 | 9.61e-09 | NA | NA |
| 5. P | P68712 | Virion membrane protein A21 | NA | 3.95e-05 | NA | NA |
| 5. P | P9WM29 | Uncharacterized protein Rv1312 | 4.74e-02 | 9.61e-09 | NA | NA |
| 5. P | Q65149 | Uncharacterized protein EP152R | NA | 1.98e-05 | NA | NA |
| 5. P | P0ADL5 | Uncharacterized protein YicN | 1.43e-02 | 8.43e-06 | NA | NA |
| 5. P | P0DSR8 | Virion membrane protein A21 | NA | 3.27e-04 | NA | NA |
| 5. P | P60672 | Envelope protein A28 homolog | NA | 7.33e-04 | NA | NA |
| 5. P | P64980 | Uncharacterized protein Mb2319 | 2.65e-03 | 5.08e-06 | NA | NA |
| 5. P | P0CA60 | Uncharacterized protein EP152R | NA | 2.77e-03 | NA | NA |
| 5. P | P20996 | Virion membrane protein A21 | NA | 3.95e-05 | NA | NA |
| 5. P | P0CA54 | Uncharacterized protein E146L | NA | 3.69e-02 | NA | NA |
| 5. P | P22403 | Protein KilB | 6.26e-05 | 8.11e-05 | NA | NA |
| 5. P | P0CA62 | Uncharacterized protein EP152R | NA | 1.42e-04 | NA | NA |
| 5. P | P45914 | Uncharacterized protein YqaR | 1.37e-03 | 1.99e-05 | NA | NA |
| 5. P | P16517 | DNA replication protein 16.7 | NA | 1.93e-03 | NA | NA |
| 5. P | Q5RF08 | Protein C1orf43 homolog | 5.37e-03 | 4.46e-03 | NA | NA |
| 5. P | P0DOM4 | Protein G3 | NA | 1.81e-02 | NA | NA |
| 5. P | O31554 | Uncharacterized protein YfjE | 2.52e-02 | 8.50e-07 | NA | NA |
| 5. P | P9WLD9 | Uncharacterized protein Rv2297 | 2.73e-03 | 5.08e-06 | NA | NA |
| 5. P | O55705 | Uncharacterized protein 061R | NA | 6.73e-03 | NA | NA |
| 5. P | O31929 | SPbeta prophage-derived uncharacterized protein YopI | 2.08e-01 | 2.54e-02 | NA | NA |
| 5. P | Q91FG7 | Uncharacterized protein 357R | NA | 7.53e-04 | NA | NA |
| 5. P | P9WLD8 | Uncharacterized protein MT2354 | 2.62e-03 | 5.08e-06 | NA | NA |
| 5. P | O28712 | Uncharacterized protein AF_1560 | 1.01e-03 | 1.24e-02 | NA | NA |