Summary
The literature section presents previous knowledge about this protein. There have been five different efforts to annotate minimal organism genome. The annotations from those efforts are given in the Literature section for completeness.
AVX54998.1
JCVISYN3A_0838
23S rRNA (guanosine(2251)-2'-O)-methyltransferase.
M. mycoides homolog: Q6MS22.
TIGRfam Classification: 2=Generic.
Category: Nonessential.
Statistics
Total GO Annotation: 40
Unique PROST Go: 6
Unique BLAST Go: 4
Unique Foldseek Go: 5
Total Homologs: 230
Unique PROST Homologs: 40
Unique BLAST Homologs: 6
Unique Foldseek Homologs: 79
Literature
Danchin and Fang [1]: 23S rRNA 2'-O-ribose G methyltransferase|modification of tRNA as well?
Yang and Tsui [2]: tRNA/rRNA methyltransferase
Antczak et al. [3]: rlmB; 23S rRNA (guanosine-2'-O-)-methyltransferase RlmB
Zhang et al. [4]: GO:0070039|rRNA (guanosine-2'-O-)-methylt ransferase activity
Bianchi et al. [5]: rlmB-like rRNA guanosine rRNA methyltransferase
Structures and Sequence Alignment
The best structural homolog that predicted by 1. PBF was
Q87VK2
(23S rRNA (guanosine-2'-O-)-methyltransferase RlmB) with a FATCAT P-Value: 0 and RMSD of 3.27 angstrom. The sequence alignment identity is 29.1%.
Structural alignment shown in left. Query protein AVX54998.1 colored as red in alignment, homolog Q87VK2 colored as blue.
Query protein AVX54998.1 is also shown in right top, homolog Q87VK2 showed in right bottom. They are colored based on secondary structures.
AVX54998.1 MNSNL--IYGKHVVFELLKKHQNMVKEIWVKDLKILNEFDLK-NTKIKVNVVSENKL----------DQLLETQTQHQGIIAQIKDYNYTPFNQL----- 82 Q87VK2 M-SQLEKIYGVHAVEALLRHHPKRVKHIWLAEGR--N--DPRVQT-L-VALASENRVTIGQAERREMDAWVE--GVHQGVVA---D--VSP-SQVWGEAM 85 AVX54998.1 IND-LNTKE-KSLVLILDQIHDPYNFGAIIRSCSLLNVD--G--IIILDK-KQVQVNSTVLKTSSGSAFDIKICKTNNLNNAIKILKNNDFWIYATNLNQ 175 Q87VK2 LDELLDRSEGPPLLLVLDGVTDPHNLGA----C-LRTADAAGALAVIVPKDKSATLTPAVRKVACGAAEVIPLVAVTNLARTLEKLQQRGLWVVGT-AGE 179 AVX54998.1 NSTDMTKIDFANKTAVIIGNEQKGVSELLTK-NSDFNVYVPSNKNIDSFNASVACSIICFWIANYLNKLS----- 244 Q87VK2 AEVELYQQDLTGPTIIIMGAEGKGMRR-LTREHCDYLVRLPMAGSVSSLNVSVATG-VCLFEA--LRQRSAKRKP 250
Go Annotations
1. PBF indicates the go terms that are found by both PROST and BLAST and Foldseek.
2. PF indicates the go terms that are found by only PROST and Foldseek.
3. BF indicates the go terms that are found by only BLAST and Foldseek.
4. PB indicates the go terms that are found by both PROST and BLAST.
5. P indicates the go terms that are found by only PROST.
6. F indicates the go terms that are found by only Foldseek.
7. B indicates the go terms that are found by only BLAST.
| Source | GO | Description |
|---|---|---|
| 1. PBF | GO:0003723 | RNA binding |
| 1. PBF | GO:0008757 | S-adenosylmethionine-dependent methyltransferase activity |
| 1. PBF | GO:0006396 | RNA processing |
| 1. PBF | GO:0008175 | tRNA methyltransferase activity |
| 1. PBF | GO:0001510 | RNA methylation |
| 1. PBF | GO:0000453 | enzyme-directed rRNA 2'-O-methylation |
| 1. PBF | GO:0005829 | cytosol |
| 1. PBF | GO:0070039 | rRNA (guanosine-2'-O-)-methyltransferase activity |
| 1. PBF | GO:0030743 | rRNA (adenosine-2'-O-)-methyltransferase activity |
| 1. PBF | GO:0046677 | response to antibiotic |
| 1. PBF | GO:0008173 | RNA methyltransferase activity |
| 2. PF | GO:0070475 | rRNA base methylation |
| 2. PF | GO:0005737 | cytoplasm |
| 2. PF | GO:0006364 | rRNA processing |
| 2. PF | GO:0070042 | rRNA (uridine-N3-)-methyltransferase activity |
| 2. PF | GO:0008168 | methyltransferase activity |
| 2. PF | GO:0032259 | methylation |
| 3. BF | GO:0052665 | tRNA (uracil-2'-O-)-methyltransferase activity |
| 3. BF | GO:0009020 | tRNA (guanosine-2'-O-)-methyltransferase activity |
| 3. BF | GO:0002938 | tRNA guanine ribose methylation |
| 4. PB | GO:0030488 | tRNA methylation |
| 4. PB | GO:0008989 | rRNA (guanine-N1-)-methyltransferase activity |
| 4. PB | GO:0000451 | rRNA 2'-O-methylation |
| 4. PB | GO:0000963 | mitochondrial RNA processing |
| 4. PB | GO:0031167 | rRNA methylation |
| 5. P | GO:0005880 | nuclear microtubule |
| 5. P | GO:0000480 | endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) |
| 5. P | GO:0070037 | rRNA (pseudouridine) methyltransferase activity |
| 5. P | GO:0032040 | small-subunit processome |
| 5. P | GO:0000472 | endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) |
| 5. P | GO:0019843 | rRNA binding |
| 6. F | GO:0008033 | tRNA processing |
| 6. F | GO:0052666 | tRNA (cytosine-2'-O-)-methyltransferase activity |
| 6. F | GO:0002132 | wobble position uridine ribose methylation |
| 6. F | GO:0002131 | wobble position cytosine ribose methylation |
| 6. F | GO:0002128 | tRNA nucleoside ribose methylation |
| 7. B | GO:0000049 | tRNA binding |
| 7. B | GO:0000154 | rRNA modification |
| 7. B | GO:0005739 | mitochondrion |
| 7. B | GO:0016423 | tRNA (guanine) methyltransferase activity |
Uniprot GO Annotations
| GO | Description |
|---|---|
| GO:0016740 | transferase activity |
| GO:0003723 | RNA binding |
| GO:0006396 | RNA processing |
| GO:0001510 | RNA methylation |
| GO:0005737 | cytoplasm |
| GO:0008168 | methyltransferase activity |
| GO:0008173 | RNA methyltransferase activity |
| GO:0032259 | methylation |
Homologs
1. PBF indicates the homologs that are found by both PROST and BLAST and Foldseek.
2. PF indicates the homologs that are found by only PROST and Foldseek.
3. BF indicates the homologs that are found by only BLAST and Foldseek.
4. PB indicates the homologs that are found by both PROST and BLAST.
5. P indicates the homologs that are found by only PROST.
6. F indicates the homologs that are found by only Foldseek.
7. B indicates the homologs that are found by only BLAST.
| Source | Homolog | Description | Fatcat Pvalue | PROST Evalue | BLAST Evalue | Foldseek TMScore |
|---|---|---|---|---|---|---|
| 1. PBF | Q9CCW4 | Uncharacterized tRNA/rRNA methyltransferase ML0324 | 0.00e+00 | 9.11e-06 | 1.73e-28 | 0.8054 |
| 1. PBF | Q6D127 | 23S rRNA (guanosine-2'-O-)-methyltransferase RlmB | 0.00e+00 | 4.48e-50 | 6.08e-29 | 0.7808 |
| 1. PBF | A1TG08 | Uncharacterized tRNA/rRNA methyltransferase Mvan_5337 | 0.00e+00 | 2.56e-07 | 4.61e-28 | 0.8032 |
| 1. PBF | P94538 | Uncharacterized tRNA/rRNA methyltransferase YsgA | 0.00e+00 | 5.77e-41 | 2.86e-28 | 0.8477 |
| 1. PBF | Q8ZKA2 | 23S rRNA (guanosine-2'-O-)-methyltransferase RlmB | 0.00e+00 | 6.68e-56 | 3.61e-29 | 0.806 |
| 1. PBF | P44906 | 23S rRNA (guanosine-2'-O-)-methyltransferase RlmB | 0.00e+00 | 1.23e-55 | 8.02e-23 | 0.8198 |
| 1. PBF | Q8DCT8 | 23S rRNA (guanosine-2'-O-)-methyltransferase RlmB | 0.00e+00 | 1.79e-58 | 1.82e-25 | 0.7794 |
| 1. PBF | Q7VQP0 | 23S rRNA (guanosine-2'-O-)-methyltransferase RlmB | 0.00e+00 | 2.27e-50 | 7.29e-26 | 0.8737 |
| 1. PBF | Q99W72 | Putative TrmH family tRNA/rRNA methyltransferase | 0.00e+00 | 4.64e-64 | 2.49e-40 | 0.677 |
| 1. PBF | Q9AGT0 | Putative TrmH family tRNA/rRNA methyltransferase | 0.00e+00 | 5.37e-63 | 3.95e-40 | 0.6755 |
| 1. PBF | Q8PM64 | 23S rRNA (guanosine-2'-O-)-methyltransferase RlmB | 0.00e+00 | 7.44e-51 | 2.97e-23 | 0.7065 |
| 1. PBF | Q7MH13 | 23S rRNA (guanosine-2'-O-)-methyltransferase RlmB | 0.00e+00 | 1.79e-58 | 1.82e-25 | 0.828 |
| 1. PBF | A0QAB6 | Uncharacterized tRNA/rRNA methyltransferase MAV_0574 | 0.00e+00 | 4.77e-07 | 2.52e-25 | 0.8078 |
| 1. PBF | Q9KNY2 | 23S rRNA (guanosine-2'-O-)-methyltransferase RlmB | 0.00e+00 | 3.00e-60 | 6.51e-29 | 0.7802 |
| 1. PBF | B2HJ20 | Uncharacterized tRNA/rRNA methyltransferase MMAR_5079 | 0.00e+00 | 7.05e-07 | 1.80e-26 | 0.8003 |
| 1. PBF | Q8ZIV4 | 23S rRNA (guanosine-2'-O-)-methyltransferase RlmB | 0.00e+00 | 3.59e-49 | 1.66e-30 | 0.8218 |
| 1. PBF | Q6FF50 | 23S rRNA (guanosine-2'-O-)-methyltransferase RlmB | 0.00e+00 | 1.25e-46 | 1.24e-24 | 0.8839 |
| 1. PBF | Q49V41 | Putative TrmH family tRNA/rRNA methyltransferase | 0.00e+00 | 7.57e-55 | 1.30e-40 | 0.7762 |
| 1. PBF | Q9RED7 | 23S rRNA (guanosine-2'-O-)-methyltransferase RlmB | 0.00e+00 | 7.05e-49 | 1.90e-14 | 0.7597 |
| 1. PBF | A0R557 | Uncharacterized tRNA/rRNA methyltransferase MSMEG_6073/MSMEI_5913 | 0.00e+00 | 4.35e-07 | 5.46e-23 | 0.8084 |
| 1. PBF | Q5HIE3 | Putative TrmH family tRNA/rRNA methyltransferase | 0.00e+00 | 5.37e-63 | 3.95e-40 | 0.6756 |
| 1. PBF | Q7MYU6 | 23S rRNA (guanosine-2'-O-)-methyltransferase RlmB | 0.00e+00 | 7.60e-50 | 1.92e-27 | 0.8181 |
| 1. PBF | Q8PAG5 | 23S rRNA (guanosine-2'-O-)-methyltransferase RlmB | 0.00e+00 | 6.56e-51 | 1.03e-23 | 0.7035 |
| 1. PBF | Q7A1Q9 | Putative TrmH family tRNA/rRNA methyltransferase | 0.00e+00 | 4.64e-64 | 2.49e-40 | 0.6755 |
| 1. PBF | Q7TW55 | Uncharacterized tRNA/rRNA methyltransferase Mb3610c | 0.00e+00 | 8.85e-07 | 3.11e-26 | 0.8066 |
| 1. PBF | Q6GJD7 | Putative TrmH family tRNA/rRNA methyltransferase | 0.00e+00 | 4.64e-64 | 2.49e-40 | 0.6767 |
| 1. PBF | Q7A794 | Putative TrmH family tRNA/rRNA methyltransferase | 0.00e+00 | 4.64e-64 | 2.49e-40 | 0.6766 |
| 1. PBF | Q8Z182 | 23S rRNA (guanosine-2'-O-)-methyltransferase RlmB | 0.00e+00 | 7.38e-55 | 1.19e-28 | 0.8163 |
| 1. PBF | P59968 | Uncharacterized tRNA/rRNA methyltransferase Mb0905 | 0.00e+00 | 8.85e-20 | 7.93e-09 | 0.8158 |
| 1. PBF | Q1B2P4 | Uncharacterized tRNA/rRNA methyltransferase Mmcs_4736 | 0.00e+00 | 1.39e-08 | 1.45e-19 | 0.7816 |
| 1. PBF | Q8CTT9 | Putative TrmH family tRNA/rRNA methyltransferase | 0.00e+00 | 2.79e-64 | 2.75e-36 | 0.6873 |
| 1. PBF | Q9JZR3 | 23S rRNA (guanosine-2'-O-)-methyltransferase RlmB | 0.00e+00 | 7.07e-48 | 1.49e-23 | 0.6499 |
| 1. PBF | P9WFY2 | Uncharacterized tRNA/rRNA methyltransferase MT0904 | 0.00e+00 | 8.85e-20 | 7.93e-09 | 0.8204 |
| 1. PBF | P75424 | Uncharacterized tRNA/rRNA methyltransferase MG252 homolog | 0.00e+00 | 1.40e-61 | 1.76e-34 | 0.8447 |
| 1. PBF | Q6GBV6 | Putative TrmH family tRNA/rRNA methyltransferase | 0.00e+00 | 4.64e-64 | 2.49e-40 | 0.6775 |
| 1. PBF | Q9HUM8 | 23S rRNA (guanosine-2'-O-)-methyltransferase RlmB | 0.00e+00 | 8.62e-59 | 2.05e-31 | 0.8036 |
| 1. PBF | B1MGY6 | Uncharacterized tRNA/rRNA methyltransferase MAB_0572 | 0.00e+00 | 1.51e-06 | 9.84e-28 | 0.8072 |
| 1. PBF | Q7VP36 | 23S rRNA (guanosine-2'-O-)-methyltransferase RlmB | 0.00e+00 | 5.05e-60 | 3.17e-25 | 0.8466 |
| 1. PBF | P74261 | Uncharacterized tRNA/rRNA methyltransferase slr1673 | 0.00e+00 | 1.71e-29 | 1.30e-10 | 0.7825 |
| 1. PBF | Q7WKX5 | 23S rRNA (guanosine-2'-O-)-methyltransferase RlmB | 0.00e+00 | 3.96e-57 | 3.06e-27 | 0.7308 |
| 1. PBF | Q8EAG8 | 23S rRNA (guanosine-2'-O-)-methyltransferase RlmB | 0.00e+00 | 7.94e-57 | 1.68e-27 | 0.7902 |
| 1. PBF | Q82XD1 | 23S rRNA (guanosine-2'-O-)-methyltransferase RlmB | 0.00e+00 | 3.06e-51 | 2.86e-28 | 0.6662 |
| 1. PBF | P63178 | 23S rRNA (guanosine-2'-O-)-methyltransferase RlmB | 0.00e+00 | 3.53e-56 | 1.06e-28 | 0.7034 |
| 1. PBF | P52393 | 23S rRNA (adenosine(1067)-2'-O)-methyltransferase | 7.77e-16 | 4.86e-36 | 4.95e-05 | 0.7836 |
| 1. PBF | A3Q6V9 | Uncharacterized tRNA/rRNA methyltransferase Mjls_5122 | 0.00e+00 | 1.73e-08 | 1.15e-19 | 0.7795 |
| 1. PBF | Q743W2 | Uncharacterized tRNA/rRNA methyltransferase MAP_0479 | 0.00e+00 | 6.81e-07 | 5.42e-24 | 0.8125 |
| 1. PBF | A1KPR5 | Uncharacterized tRNA/rRNA methyltransferase BCG_3644c | 0.00e+00 | 1.14e-06 | 2.08e-26 | 0.8075 |
| 1. PBF | A1UMF4 | Uncharacterized tRNA/rRNA methyltransferase Mkms_4822 | 0.00e+00 | 1.39e-08 | 1.45e-19 | 0.7833 |
| 1. PBF | Q9F5K6 | 23S rRNA (uridine(2479)-2'-O)-methyltransferase | 0.00e+00 | 2.81e-29 | 9.26e-07 | 0.8195 |
| 1. PBF | P47494 | Uncharacterized tRNA/rRNA methyltransferase MG252 | 0.00e+00 | 1.18e-67 | 5.72e-36 | 0.876 |
| 1. PBF | O51468 | Uncharacterized tRNA/rRNA methyltransferase BB_0516 | 0.00e+00 | 1.80e-54 | 1.48e-38 | 0.8825 |
| 1. PBF | Q87VK2 | 23S rRNA (guanosine-2'-O-)-methyltransferase RlmB | 0.00e+00 | 1.42e-54 | 2.24e-27 | 0.7615 |
| 1. PBF | Q7W7I7 | 23S rRNA (guanosine-2'-O-)-methyltransferase RlmB | 0.00e+00 | 3.96e-57 | 3.06e-27 | 0.7111 |
| 1. PBF | Q6LM40 | 23S rRNA (guanosine-2'-O-)-methyltransferase RlmB | 0.00e+00 | 7.04e-56 | 1.10e-24 | 0.8327 |
| 1. PBF | Q7VTK4 | 23S rRNA (guanosine-2'-O-)-methyltransferase RlmB | 1.67e-14 | 3.96e-57 | 3.06e-27 | 0.6847 |
| 1. PBF | P9WFY4 | Uncharacterized tRNA/rRNA methyltransferase MT3685 | 0.00e+00 | 1.56e-06 | 2.61e-26 | 0.8076 |
| 1. PBF | Q83CW6 | 23S rRNA (guanosine-2'-O-)-methyltransferase RlmB | 0.00e+00 | 1.93e-60 | 8.50e-28 | 0.797 |
| 1. PBF | B8ZUB0 | Uncharacterized tRNA/rRNA methyltransferase MLBr00324 | 0.00e+00 | 9.11e-06 | 1.73e-28 | 0.8085 |
| 1. PBF | Q9CJP3 | 23S rRNA (guanosine-2'-O-)-methyltransferase RlmB | 0.00e+00 | 2.42e-47 | 3.84e-21 | 0.829 |
| 1. PBF | Q88DE7 | 23S rRNA (guanosine-2'-O-)-methyltransferase RlmB | 0.00e+00 | 4.47e-55 | 5.68e-28 | 0.7572 |
| 1. PBF | Q87D65 | 23S rRNA (guanosine-2'-O-)-methyltransferase RlmB | 0.00e+00 | 3.09e-47 | 1.28e-27 | 0.7385 |
| 1. PBF | P63179 | 23S rRNA (guanosine-2'-O-)-methyltransferase RlmB | 0.00e+00 | 3.53e-56 | 1.06e-28 | 0.7616 |
| 1. PBF | A4T5L0 | Uncharacterized tRNA/rRNA methyltransferase Mflv_1447 | 0.00e+00 | 7.90e-07 | 3.13e-27 | 0.8186 |
| 1. PBF | A0PV26 | Uncharacterized tRNA/rRNA methyltransferase MUL_4155 | 0.00e+00 | 3.88e-07 | 1.84e-26 | 0.8008 |
| 1. PBF | P18644 | 23S rRNA (adenosine(1067)-2'-O)-methyltransferase | 5.55e-16 | 1.70e-31 | 1.14e-06 | 0.7615 |
| 1. PBF | Q5HRM1 | Putative TrmH family tRNA/rRNA methyltransferase | 0.00e+00 | 2.79e-64 | 2.75e-36 | 0.6869 |
| 1. PBF | Q9JUU8 | 23S rRNA (guanosine-2'-O-)-methyltransferase RlmB | 0.00e+00 | 2.23e-49 | 1.71e-25 | 0.6622 |
| 1. PBF | P52391 | 23S rRNA (adenosine(1067)-2'-O)-methyltransferase | 2.22e-16 | 3.61e-34 | 1.73e-09 | 0.806 |
| 1. PBF | P63180 | 23S rRNA (guanosine-2'-O-)-methyltransferase RlmB | 0.00e+00 | 3.53e-56 | 1.06e-28 | 0.7333 |
| 1. PBF | Q9PC00 | 23S rRNA (guanosine-2'-O-)-methyltransferase RlmB | 0.00e+00 | 5.76e-50 | 1.92e-28 | 0.7194 |
| 1. PBF | O30272 | Uncharacterized tRNA/rRNA methyltransferase AF_2399 | 0.00e+00 | 4.78e-53 | 2.62e-21 | 0.9022 |
| 1. PBF | Q8Y016 | 23S rRNA (guanosine-2'-O-)-methyltransferase RlmB | 0.00e+00 | 1.48e-55 | 2.46e-23 | 0.7243 |
| 1. PBF | Q87L11 | 23S rRNA (guanosine-2'-O-)-methyltransferase RlmB | 0.00e+00 | 3.72e-55 | 1.80e-25 | 0.8099 |
| 1. PBF | Q06753 | Putative TrmH family tRNA/rRNA methyltransferase YacO | 0.00e+00 | 7.82e-62 | 5.58e-36 | 0.8637 |
| 1. PBF | A5U8Q4 | Uncharacterized tRNA/rRNA methyltransferase MRA_3618 | 0.00e+00 | 1.56e-06 | 2.61e-26 | 0.8076 |
| 1. PBF | Q4L3J1 | Putative TrmH family tRNA/rRNA methyltransferase | 0.00e+00 | 8.16e-59 | 9.87e-37 | 0.6793 |
| 1. PBF | Q7NYX3 | 23S rRNA (guanosine-2'-O-)-methyltransferase RlmB | 0.00e+00 | 1.34e-53 | 3.49e-27 | 0.6644 |
| 2. PF | P37995 | Ribosomal RNA small subunit methyltransferase E | 3.54e-04 | 6.33e-03 | NA | 0.4933 |
| 2. PF | Q9ZKD2 | Ribosomal RNA small subunit methyltransferase E | 1.03e-03 | 6.10e-04 | NA | 0.5093 |
| 2. PF | O25138 | Ribosomal RNA small subunit methyltransferase E | 7.99e-04 | 3.40e-04 | NA | 0.5176 |
| 2. PF | O51333 | Ribosomal RNA small subunit methyltransferase E 2 | 4.15e-04 | 5.06e-04 | NA | 0.475 |
| 2. PF | O51089 | Ribosomal RNA small subunit methyltransferase E 1 | 1.63e-03 | 9.13e-03 | NA | 0.5697 |
| 2. PF | P0AGL9 | Ribosomal RNA small subunit methyltransferase E | 2.04e-04 | 1.19e-02 | NA | 0.5034 |
| 2. PF | Q92J59 | Ribosomal RNA small subunit methyltransferase E | 1.49e-03 | 6.04e-04 | NA | 0.4782 |
| 2. PF | O83075 | Ribosomal RNA small subunit methyltransferase E | 1.66e-04 | 1.89e-05 | NA | 0.5629 |
| 2. PF | O50188 | Ribosomal RNA small subunit methyltransferase E | 1.68e-03 | 3.18e-03 | NA | 0.5229 |
| 3. BF | P0AGJ6 | Uncharacterized tRNA/rRNA methyltransferase YfiF | 1.11e-16 | NA | 7.12e-13 | 0.8111 |
| 3. BF | P74328 | Uncharacterized tRNA/rRNA methyltransferase slr0955 | 1.05e-14 | NA | 3.46e-31 | 0.6981 |
| 3. BF | P0AGJ4 | tRNA (guanosine(18)-2'-O)-methyltransferase | 6.89e-09 | NA | 7.22e-16 | 0.7945 |
| 3. BF | P32813 | Putative tRNA (cytidine(34)-2'-O)-methyltransferase | 7.41e-12 | NA | 0.003 | 0.8077 |
| 3. BF | P44703 | Uncharacterized tRNA/rRNA methyltransferase HI_0424 | 0.00e+00 | NA | 4.38e-04 | 0.8176 |
| 3. BF | A0LHE3 | Ribosomal RNA small subunit methyltransferase G 2 | 3.10e-10 | NA | 6.03e-04 | 0.7339 |
| 3. BF | O51081 | tRNA (guanosine(18)-2'-O)-methyltransferase | 1.20e-12 | NA | 1.78e-10 | 0.8339 |
| 3. BF | Q5SM16 | tRNA (guanosine(18)-2'-O)-methyltransferase | 4.37e-11 | NA | 3.50e-21 | 0.8082 |
| 3. BF | Q72GI1 | tRNA (guanosine(18)-2'-O)-methyltransferase | 9.96e-11 | NA | 3.50e-21 | 0.7994 |
| 3. BF | Q4JB16 | tRNA (cytidine-2'-O-)-methyltransferase TrmJ | 9.65e-11 | NA | 8.28e-04 | 0.7304 |
| 3. BF | P0AGJ3 | tRNA (guanosine(18)-2'-O)-methyltransferase | 8.03e-09 | NA | 7.22e-16 | 0.7936 |
| 3. BF | B2IBT9 | tRNA (cytidine(34)-2'-O)-methyltransferase | 7.88e-15 | NA | 3.11e-05 | 0.804 |
| 3. BF | O67577 | tRNA (guanosine(18)-2'-O)-methyltransferase | 2.31e-11 | NA | 7.29e-15 | 0.8496 |
| 4. PB | P63177 | 23S rRNA (guanosine-2'-O-)-methyltransferase RlmB | 0.00e+00 | 3.53e-56 | 1.06e-28 | NA |
| 4. PB | Q99J25 | rRNA methyltransferase 1, mitochondrial | 0.00e+00 | 1.67e-17 | 7.83e-10 | NA |
| 4. PB | Q6IN84 | rRNA methyltransferase 1, mitochondrial | 0.00e+00 | 4.50e-09 | 1.56e-14 | NA |
| 4. PB | P9WFY3 | Uncharacterized tRNA/rRNA methyltransferase Rv0881 | 0.00e+00 | 3.51e-20 | 2.72e-08 | NA |
| 4. PB | O94631 | rRNA methyltransferase 1, mitochondrial | 0.00e+00 | 3.39e-20 | 3.65e-12 | NA |
| 4. PB | P9WFY5 | Uncharacterized tRNA/rRNA methyltransferase Rv3579c | 0.00e+00 | 1.56e-06 | 2.61e-26 | NA |
| 5. P | Q8ZW45 | Ribosomal RNA small subunit methyltransferase Nep1 | 1.01e-02 | 1.23e-04 | NA | NA |
| 5. P | A0B5L3 | Ribosomal RNA small subunit methyltransferase Nep1 | 1.46e-02 | 8.34e-04 | NA | NA |
| 5. P | Q5JI44 | Ribosomal RNA small subunit methyltransferase Nep1 | 2.18e-02 | 4.84e-05 | NA | NA |
| 5. P | P57488 | Ribosomal RNA small subunit methyltransferase E | 2.90e-04 | 4.36e-04 | NA | NA |
| 5. P | O29524 | Ribosomal RNA small subunit methyltransferase Nep1 | 2.82e-02 | 5.92e-04 | NA | NA |
| 5. P | A1RVH0 | Ribosomal RNA small subunit methyltransferase Nep1 | 8.32e-03 | 6.68e-05 | NA | NA |
| 5. P | P0AGL7 | Ribosomal RNA small subunit methyltransferase E | 2.56e-04 | 1.19e-02 | NA | NA |
| 5. P | Q5JF45 | tRNA (pseudouridine(54)-N(1))-methyltransferase | 6.50e-03 | 2.45e-02 | NA | NA |
| 5. P | A3MWJ1 | Ribosomal RNA small subunit methyltransferase Nep1 | 1.14e-02 | 4.14e-05 | NA | NA |
| 5. P | Q9V0M0 | Ribosomal RNA small subunit methyltransferase Nep1 | 3.09e-02 | 3.08e-04 | NA | NA |
| 5. P | Q9KKP3 | Putative pseudouridine methyltransferase | 3.33e-03 | 4.26e-02 | NA | NA |
| 5. P | A4WMI3 | Ribosomal RNA small subunit methyltransferase Nep1 | 9.19e-03 | 2.32e-05 | NA | NA |
| 5. P | B6YTM6 | Ribosomal RNA small subunit methyltransferase Nep1 | 2.50e-02 | 4.36e-04 | NA | NA |
| 5. P | A2STS4 | tRNA (pseudouridine(54)-N(1))-methyltransferase | 5.29e-02 | 5.51e-03 | NA | NA |
| 5. P | B6YVU7 | tRNA (pseudouridine(54)-N(1))-methyltransferase | 9.54e-03 | 7.68e-03 | NA | NA |
| 5. P | P44627 | Ribosomal RNA small subunit methyltransferase E | 3.03e-04 | 2.06e-03 | NA | NA |
| 5. P | Q9V0N8 | tRNA (pseudouridine(54)-N(1))-methyltransferase | 1.40e-02 | 1.96e-02 | NA | NA |
| 5. P | Q06287 | Ribosomal RNA small subunit methyltransferase NEP1 | 2.33e-02 | 7.07e-03 | NA | NA |
| 5. P | Q57977 | Ribosomal RNA small subunit methyltransferase Nep1 | 2.74e-02 | 1.01e-02 | NA | NA |
| 5. P | P0AGL8 | Ribosomal RNA small subunit methyltransferase E | 2.41e-04 | 1.19e-02 | NA | NA |
| 5. P | A0B6S6 | tRNA (pseudouridine(54)-N(1))-methyltransferase | 1.99e-02 | 2.80e-02 | NA | NA |
| 5. P | Q97WJ0 | Ribosomal RNA small subunit methyltransferase Nep1 | 1.68e-02 | 5.83e-03 | NA | NA |
| 5. P | A3DNG9 | Ribosomal RNA small subunit methyltransferase Nep1 | 1.07e-02 | 6.39e-03 | NA | NA |
| 5. P | Q12XH2 | tRNA (pseudouridine(54)-N(1))-methyltransferase | 2.41e-03 | 8.75e-04 | NA | NA |
| 5. P | Q2FS92 | tRNA (pseudouridine(54)-N(1))-methyltransferase | 1.40e-02 | 6.75e-03 | NA | NA |
| 5. P | Q979E4 | Ribosomal RNA small subunit methyltransferase Nep1 | 1.95e-02 | 2.61e-02 | NA | NA |
| 5. P | Q96YP4 | Ribosomal RNA small subunit methyltransferase Nep1 | 2.68e-02 | 8.48e-05 | NA | NA |
| 5. P | Q9W4J5 | Ribosomal RNA small subunit methyltransferase NEP1 | 1.49e-02 | 1.53e-03 | NA | NA |
| 5. P | Q9YES9 | Ribosomal RNA small subunit methyltransferase Nep1 | 1.53e-02 | 1.48e-02 | NA | NA |
| 5. P | Q9HJ48 | Ribosomal RNA small subunit methyltransferase Nep1 | 2.04e-02 | 1.30e-02 | NA | NA |
| 5. P | D4GTL8 | tRNA (pseudouridine(54)-N(1))-methyltransferase | 4.87e-03 | 2.97e-02 | NA | NA |
| 5. P | Q0VNR6 | Putative pseudouridine methyltransferase | 5.70e-06 | 4.45e-03 | NA | NA |
| 5. P | Q8U1E6 | Ribosomal RNA small subunit methyltransferase Nep1 | 2.42e-02 | 1.53e-03 | NA | NA |
| 5. P | Q9HNR6 | tRNA (pseudouridine(54)-N(1))-methyltransferase | 2.86e-03 | 3.87e-02 | NA | NA |
| 5. P | B1YD95 | Ribosomal RNA small subunit methyltransferase Nep1 | 1.44e-02 | 1.37e-05 | NA | NA |
| 5. P | Q8K9E4 | Ribosomal RNA small subunit methyltransferase E | 1.47e-04 | 5.40e-06 | NA | NA |
| 5. P | B0R6T1 | tRNA (pseudouridine(54)-N(1))-methyltransferase | 2.69e-03 | 3.87e-02 | NA | NA |
| 5. P | Q96UP2 | Ribosomal RNA small subunit methyltransferase NEP1 | 2.16e-02 | 2.32e-05 | NA | NA |
| 5. P | O50109 | tRNA (pseudouridine(54)-N(1))-methyltransferase | 3.75e-05 | 3.14e-02 | NA | NA |
| 5. P | O50087 | Ribosomal RNA small subunit methyltransferase Nep1 | 2.79e-02 | 1.65e-03 | NA | NA |
| 6. F | A8AD50 | tRNA (cytidine/uridine-2'-O-)-methyltransferase TrmJ | 2.48e-09 | NA | NA | 0.6983 |
| 6. F | Q1C5G8 | tRNA (cytidine/uridine-2'-O-)-methyltransferase TrmJ | 2.89e-09 | NA | NA | 0.6859 |
| 6. F | Q2NS29 | tRNA (cytidine/uridine-2'-O-)-methyltransferase TrmJ | 3.41e-09 | NA | NA | 0.6994 |
| 6. F | Q6D257 | tRNA (cytidine/uridine-2'-O-)-methyltransferase TrmJ | 2.34e-09 | NA | NA | 0.6794 |
| 6. F | C6X9I5 | tRNA (cytidine(34)-2'-O)-methyltransferase | 1.48e-12 | NA | NA | 0.8288 |
| 6. F | A3DN06 | tRNA (cytidine(56)-2'-O)-methyltransferase | 2.26e-06 | NA | NA | 0.6355 |
| 6. F | Q8TX72 | tRNA (cytidine(56)-2'-O)-methyltransferase | 2.61e-07 | NA | NA | 0.6704 |
| 6. F | A1RY31 | tRNA (cytidine(56)-2'-O)-methyltransferase | 3.74e-07 | NA | NA | 0.6787 |
| 6. F | Q2FT21 | tRNA (cytidine(56)-2'-O)-methyltransferase | 9.66e-07 | NA | NA | 0.6539 |
| 6. F | P66974 | tRNA (cytidine/uridine-2'-O-)-methyltransferase TrmJ | 2.32e-09 | NA | NA | 0.6788 |
| 6. F | P74516 | Putative tRNA (cytidine(34)-2'-O)-methyltransferase | 3.22e-15 | NA | NA | 0.859 |
| 6. F | Q31XV8 | tRNA (cytidine/uridine-2'-O-)-methyltransferase TrmJ | 2.93e-09 | NA | NA | 0.6792 |
| 6. F | Q721N0 | Putative tRNA (cytidine(34)-2'-O)-methyltransferase | 1.03e-12 | NA | NA | 0.7801 |
| 6. F | P0AE03 | tRNA (cytidine/uridine-2'-O-)-methyltransferase TrmJ | 2.72e-09 | NA | NA | 0.685 |
| 6. F | Q12E50 | tRNA (cytidine(34)-2'-O)-methyltransferase | 3.95e-11 | NA | NA | 0.7156 |
| 6. F | Q9YAD3 | tRNA (cytidine(56)-2'-O)-methyltransferase | 1.07e-06 | NA | NA | 0.6436 |
| 6. F | Q21LN7 | tRNA (cytidine(34)-2'-O)-methyltransferase | 1.01e-11 | NA | NA | 0.7682 |
| 6. F | D7A3L6 | tRNA (cytidine(34)-2'-O)-methyltransferase | 6.66e-16 | NA | NA | 0.9012 |
| 6. F | Q7N222 | tRNA (cytidine/uridine-2'-O-)-methyltransferase TrmJ | 2.05e-09 | NA | NA | 0.6875 |
| 6. F | Q48V41 | Putative tRNA (cytidine(34)-2'-O)-methyltransferase | 5.89e-11 | NA | NA | 0.6441 |
| 6. F | P54461 | Ribosomal RNA small subunit methyltransferase E | 2.22e-03 | NA | NA | 0.4292 |
| 6. F | Q1CKB1 | tRNA (cytidine/uridine-2'-O-)-methyltransferase TrmJ | 3.30e-09 | NA | NA | 0.6857 |
| 6. F | P47588 | Putative tRNA (cytidine(34)-2'-O)-methyltransferase | 5.93e-13 | NA | NA | 0.7341 |
| 6. F | Q0T1Y7 | tRNA (cytidine/uridine-2'-O-)-methyltransferase TrmJ | 2.85e-09 | NA | NA | 0.6792 |
| 6. F | Q975T9 | tRNA (cytidine(56)-2'-O)-methyltransferase | 7.60e-07 | NA | NA | 0.6396 |
| 6. F | Q0TEV3 | tRNA (cytidine/uridine-2'-O-)-methyltransferase TrmJ | 2.78e-09 | NA | NA | 0.6984 |
| 6. F | Q2NF55 | tRNA (cytidine(56)-2'-O)-methyltransferase | 1.38e-07 | NA | NA | 0.6641 |
| 6. F | C7BSD3 | tRNA (cytidine(34)-2'-O)-methyltransferase | 5.62e-11 | NA | NA | 0.6933 |
| 6. F | P72667 | Ribosomal RNA small subunit methyltransferase E | 3.27e-03 | NA | NA | 0.5409 |
| 6. F | P9WGX0 | Ribosomal RNA small subunit methyltransferase E | 1.05e-04 | NA | NA | 0.5298 |
| 6. F | A2RKW7 | Putative tRNA (cytidine(34)-2'-O)-methyltransferase | 2.00e-11 | NA | NA | 0.6964 |
| 6. F | A1WBM9 | tRNA (cytidine(34)-2'-O)-methyltransferase | 1.58e-11 | NA | NA | 0.7236 |
| 6. F | A7MGX5 | tRNA (cytidine/uridine-2'-O-)-methyltransferase TrmJ | 2.64e-09 | NA | NA | 0.706 |
| 6. F | A2BLW3 | tRNA (cytidine(56)-2'-O)-methyltransferase | 1.10e-06 | NA | NA | 0.6292 |
| 6. F | P67203 | Ribosomal RNA small subunit methyltransferase E | 1.02e-04 | NA | NA | 0.5299 |
| 6. F | Q3YZ20 | tRNA (cytidine/uridine-2'-O-)-methyltransferase TrmJ | 2.55e-09 | NA | NA | 0.6795 |
| 6. F | Q1R8K0 | tRNA (cytidine/uridine-2'-O-)-methyltransferase TrmJ | 3.03e-09 | NA | NA | 0.6793 |
| 6. F | Q57LG7 | tRNA (cytidine/uridine-2'-O-)-methyltransferase TrmJ | 2.52e-09 | NA | NA | 0.6924 |
| 6. F | P75257 | Putative tRNA (cytidine(34)-2'-O)-methyltransferase | 2.14e-12 | NA | NA | 0.7147 |
| 6. F | A7I7T4 | tRNA (cytidine(56)-2'-O)-methyltransferase | 4.72e-06 | NA | NA | 0.6363 |
| 6. F | Q12Z63 | tRNA (cytidine(56)-2'-O)-methyltransferase | 1.53e-06 | NA | NA | 0.6481 |
| 6. F | A4TMV6 | tRNA (cytidine/uridine-2'-O-)-methyltransferase TrmJ | 4.35e-09 | NA | NA | 0.6913 |
| 6. F | Q74Y93 | tRNA (cytidine(34)-2'-O)-methyltransferase | 5.84e-11 | NA | NA | 0.7383 |
| 6. F | Q9YAD8 | Uncharacterized protein APE_2001.1 | 6.00e-07 | NA | NA | 0.667 |
| 6. F | Q8Q0Q0 | tRNA (cytidine(56)-2'-O)-methyltransferase | 1.42e-06 | NA | NA | 0.6569 |
| 6. F | A1JKQ0 | tRNA (cytidine/uridine-2'-O-)-methyltransferase TrmJ | 4.14e-09 | NA | NA | 0.6782 |
| 6. F | Q5PNG3 | tRNA (cytidine/uridine-2'-O-)-methyltransferase TrmJ | 2.11e-09 | NA | NA | 0.6852 |
| 6. F | Q8TL02 | tRNA (cytidine(56)-2'-O)-methyltransferase | 1.98e-06 | NA | NA | 0.658 |
| 6. F | A9A624 | tRNA (cytidine(56)-2'-O)-methyltransferase | 2.35e-07 | NA | NA | 0.636 |
| 6. F | A4YJ14 | tRNA (cytidine(56)-2'-O)-methyltransferase | 1.05e-06 | NA | NA | 0.6212 |
| 6. F | A3NR15 | tRNA (cytidine(34)-2'-O)-methyltransferase | 4.64e-11 | NA | NA | 0.7473 |
| 6. F | Q8XA83 | tRNA (cytidine/uridine-2'-O-)-methyltransferase TrmJ | 2.58e-09 | NA | NA | 0.6792 |
| 6. F | B8CHC9 | tRNA (cytidine(34)-2'-O)-methyltransferase | 3.55e-12 | NA | NA | 0.8108 |
| 6. F | P44676 | Uncharacterized tRNA/rRNA methyltransferase HI_0380 | 4.56e-09 | NA | NA | 0.6465 |
| 6. F | O66552 | Ribosomal RNA small subunit methyltransferase E | 2.99e-03 | NA | NA | 0.4526 |
| 6. F | O27185 | tRNA (cytidine(56)-2'-O)-methyltransferase | 8.62e-07 | NA | NA | 0.6294 |
| 6. F | P0AE02 | tRNA (cytidine/uridine-2'-O-)-methyltransferase TrmJ | 2.71e-09 | NA | NA | 0.6853 |
| 6. F | P44868 | tRNA (cytidine(34)-2'-O)-methyltransferase | 1.03e-11 | NA | NA | 0.7549 |
| 6. F | A4QNL8 | rRNA methyltransferase 3, mitochondrial | 9.28e-12 | NA | NA | 0.7017 |
| 6. F | Q667X9 | tRNA (cytidine/uridine-2'-O-)-methyltransferase TrmJ | 4.16e-09 | NA | NA | 0.6923 |
| 6. F | P66975 | tRNA (cytidine/uridine-2'-O-)-methyltransferase TrmJ | 2.40e-09 | NA | NA | 0.6432 |
| 6. F | O31590 | Putative tRNA (cytidine(34)-2'-O)-methyltransferase | 5.13e-12 | NA | NA | 0.7692 |
| 6. F | A3CVQ1 | tRNA (cytidine(56)-2'-O)-methyltransferase | 2.13e-06 | NA | NA | 0.5811 |
| 6. F | A0RYD1 | tRNA (cytidine(56)-2'-O)-methyltransferase | 1.47e-07 | NA | NA | 0.6778 |
| 6. F | Q0BBL1 | tRNA (cytidine(34)-2'-O)-methyltransferase | 4.51e-11 | NA | NA | 0.738 |
| 6. F | Q6GPJ4 | rRNA methyltransferase 3, mitochondrial | 1.16e-11 | NA | NA | 0.7117 |
| 6. F | A0A0H2ZF87 | tRNA (cytidine/uridine/adenosine-2'-O-)-methyltransferase TrmJ | 3.40e-09 | NA | NA | 0.6893 |
| 6. F | P69001 | Putative tRNA (cytidine(34)-2'-O)-methyltransferase | 9.75e-13 | NA | NA | 0.7719 |
| 6. F | A2SQM4 | tRNA (cytidine(56)-2'-O)-methyltransferase | 1.48e-06 | NA | NA | 0.635 |
| 6. F | A0B9Q9 | tRNA (cytidine(56)-2'-O)-methyltransferase | 4.92e-07 | NA | NA | 0.6503 |
| 6. F | Q7CJN8 | tRNA (cytidine/uridine-2'-O-)-methyltransferase TrmJ | 3.29e-09 | NA | NA | 0.6859 |
| 6. F | Q32D32 | tRNA (cytidine/uridine-2'-O-)-methyltransferase TrmJ | 2.49e-09 | NA | NA | 0.6797 |
| 6. F | A6TCF3 | tRNA (cytidine/uridine-2'-O-)-methyltransferase TrmJ | 2.67e-09 | NA | NA | 0.6855 |
| 6. F | A5ULQ9 | tRNA (cytidine(56)-2'-O)-methyltransferase | 7.10e-07 | NA | NA | 0.6751 |
| 6. F | A0KAS4 | tRNA (cytidine(34)-2'-O)-methyltransferase | 4.24e-11 | NA | NA | 0.7488 |
| 6. F | A1AE69 | tRNA (cytidine/uridine-2'-O-)-methyltransferase TrmJ | 2.84e-09 | NA | NA | 0.6792 |
| 6. F | P0AGJ8 | tRNA (cytidine(34)-2'-O)-methyltransferase | 2.73e-11 | NA | NA | 0.7524 |
| 6. F | A0KEQ6 | tRNA (cytidine(34)-2'-O)-methyltransferase | 5.67e-12 | NA | NA | 0.7823 |
| 6. F | Q042B4 | Putative RNA (cytidine(34)-2'-O)-methyltransferase | 2.88e-12 | NA | NA | 0.8242 |
| 7. B | Q9VW14 | rRNA methyltransferase 3, mitochondrial | 7.76e-09 | NA | 2.56e-07 | NA |
| 7. B | P0AGJ5 | Uncharacterized tRNA/rRNA methyltransferase YfiF | 1.11e-16 | NA | 7.12e-13 | NA |
| 7. B | P0AGJ2 | tRNA (guanosine(18)-2'-O)-methyltransferase | 8.48e-09 | NA | 7.22e-16 | NA |
| 7. B | P25270 | rRNA methyltransferase 1, mitochondrial | 2.81e-14 | NA | 3.35e-09 | NA |
| 7. B | Q13395 | Probable methyltransferase TARBP1 | 2.82e-02 | NA | 3.06e-05 | NA |
| 7. B | Q76NT0 | rRNA methyltransferase 1, mitochondrial | 4.52e-09 | NA | 4.37e-15 | NA |